Dr Sarah Sasson

Senior Lecturer

BA(English) BSc (Hons I Immunology) MBBS(Hons) PhD FRACP FRCPA

Medicine & Health

The Kirby Institute

Sarah is Head of the Immunovirology and Pathogenesis Program and Scientia Senior Lecturer at The Kirby Institute 91ɫ��Ƭ as well as a Clinical Immunologist & Immunopathologist at NSW Health Pathology ICPMR Westmead Hospital. She graduated from a BSc(HonsI)/BA (English) prior to a combined MBBS(Hons)/PhD program. Sarah completed specialist medical training in Clinical Immunology and Immunopathology at St Vincent's, Royal Prince Alfred, Concord, Liverpool and Campbelltown Hospitals and gained dual fellowships of the Royal Australasian College of Physicians and Royal College of Pathologists Australasia in 2017. From 2018-2019 Sarah undertook postdoctoral studies at the University of Oxford investigating autoimmune toxicities of immune checkpoint inhibitors in Professor Paul Klenerman's laboratory.

Sarah's broad research area is human translational Immunology. Her particular interests include the role of�� T cells in the control of cancers and sepsis as well as COVID-19 in immunocompromised people.

Sarah additionally works in the Medical Humanities and Science Communication, having published the international short-story collection��Signs of Life —an anthology (MoshPit Publishing, 2021) and literary fiction novel�� (Affirm Press, 2024). Sarah is a regular contributor to .��

Broad Research Areas:
Immunology, Infectious Diseases, Cancer Immunology, Immune Checkpoint Inhibitors, Mucosal Immunology, Sepsis

Qualifications:
BA, BSc(Hons I), MBBS(Hons), PhD, FRACP, FRCPA

Publications:

Phone

83822829

E-mail

ssasson@kirby.unsw.edu.au

Book Chapters | 2026

Maiden MJ; Sasson SC, 2026, '16 Multi-organ dysfunction syndrome', in Oh's Intensive Care Manual, Elsevier, pp. 127 - 136,
Journal articles | 2026

Carey DL; Ahlenstiel G; Brilot F; Brown DA; Bull R; Crowther H; Cunningham A; Davenport MP; Diamond P; Hamad N; Johnston A; Kelleher AD; Lee FJ; Matthews GV; Petoumenos K; Quichua GC; Swaminathan S; Trotman J; Turville S; Vukic S; Wong P; Sasson SC, 2026, 'Comparison of immunity-boosting regimens for COVID-19 upon initiation of immunosuppressive therapy (CIRCUIT): study protocol for a randomised, controlled clinical trial', BMJ Open, 16, pp. e115259,

Journal articles | 2026

Chan KL; Abadir EA; Aklilu E; Baldwin K; Banovic T; Batt T; Came NA; Cross D; Deo S; Fleming S; Gillis D; Gorniak MB; Kodituwakku A; Nguyen V; Petrasich MN; Rabade NR; Ruskova A; Sasson SC; Sewell WA; Stone L; Wei AH; Wilson JC; Jain P; Westerman DA, 2026, 'Flow cytometric assessment of measurable residual disease in acute myeloid leukaemia: a summary of current Australasian practice and future directions', Internal Medicine Journal, 56, pp. 280 - 287,

Journal articles | 2026

Crammond P; Hastak P; Delaney A; Sasson SC, 2026, 'Taking its TOLL: the role of toll-like receptor 4 in human health and disease, and its potential as a therapeutic target', Frontiers in Immunology, 17,

Journal articles | 2026

Karas PL; Sivasubramaniam V; Thomson C; Sasson SC; Plit M; Darley DR, 2026, 'Systematic Reporting of Transbronchial Biopsy Eosinophils Defines an Independent Histologic Predictor of Chronic Lung Allograft Dysfunction', JOURNAL OF HEART AND LUNG TRANSPLANTATION, 45, pp. 540 - 540

Journal articles | 2026

Spann BC; Viswanathan S; Anderson M; Das R; Tran T; Sasson SC; P’Ng CH, 2026, 'Concurrent renal AL amyloidosis, light chain crystalline podocytopathy and light chain proximal tubulopathy: case report', Pathology,

Journal articles | 2026

Wilson JG; Grandits GA; Grund B; Mistry SS; Leroux C; Ringor A; Aggarwal NR; Murray DD; Barkauskas CE; Brown SM; Higgs E; Shaw-Saliba K; Rupert A; Kan VL; Beitler JR; Awan O; Sturgill JL; Dawood H; Kalil AC; Kalomenidis I; Duggal A; Sasson SC; Ho MQ; Nguyen HH; Lundgren JD; Ginde AA; Self WH; Lane HC; Matthay MA; Rogers AJ, 2026, 'Prognostic Value of Lung Injury Biomarkers in Patients Hospitalized With COVID-19 Without Respiratory Failure at Admission', Critical Care Medicine,

Journal articles | 2026

Wu L; Wentworth JM; Liddle C; Fewings N; Carlino M; Brown DA; Clifton-Bligh R; Long GV; Scolyer RA; Norris N; Sasson SC; Tsang VH; Menzies AM; Gunton JE, 2026, 'Pancreatic volume and immune biomarkers predict checkpoint inhibitor-associated autoimmune diabetes in humans', Journal of Clinical Investigation, 136,

Journal articles | 2026

Xie SZ; Salem JE; Nagrial A; Menzies A; Thomas L; Ramanathan S; Berglund LJ; Sasson SC; Grey AC; Habib R; Wong M; Carlino MS; Jeffrey B; Mo J; Lin MW, 2026, 'Immune checkpoint inhibitor cardiomyotoxicity: a case series of five patients and development of a clinical management algorithm', Internal Medicine Journal, 56, pp. 902 - 907,

Journal articles | 2025

FitzPatrick MEB; Antanaviciute A; Dunstan M; Künnapuu K; Trzupek D; Provine NM; Dooley K; Zhang JY; Irwin SL; Garner LC; Pernes JI; Ferreira RC; Sasson SC; Aschenbrenner D; Agarwal D; Rodrigues A; Howarth L; Brain O; Ruane D; Soilleux E; Teichmann SA; Dendrou CA; Simmons A; Uhlig HH; Todd JA; Klenerman P, 2025, 'Immune–epithelial–stromal networks define the cellular ecosystem of the small intestine in celiac disease', Nature Immunology, 26, pp. 947 - 962,

Journal articles | 2025

Hastak P; Phetsouphanh C; Zhang ZH; Bull RA; Shrestha LB; Klemm V; Louie R; Luciani F; Munier CML; Hoppé AC; Keoshkerian E; Beaton B; Rankin K; Wong A; Trotman J; Kelleher AD; Sasson SC, 2025, 'Expanded CD16+CD56+Granzyme B+ NK like CD8+ T cells an off target effect of bruton’s tyrosine kinase inhibitors in Waldenström macroglobulinemia', Scientific Reports, 15, pp. 34641,

Journal articles | 2025

Pathmanandavel K; Lee A; Dela Cruz M; Culican S; Campbell D; Acebes M; Emerson J; Ong L; Brown D; Sasson S; Lin MW; Berglund L, 2025, 'Are these the clones you're looking for? Direct immunofluorescence and flow cytometry in monoclonal gammopathy of renal significance', Pathology, 57, pp. S26 - S26,

Journal articles | 2025

Venkatesh K; Schlub TE; Barreto SG; Andersen CR; Davenport MP; Delaney A; Kaambwa B; Bihari S; Pilcher D; Sasson SC, 2025, 'A prediction model for ‘ICU mortality or prolonged ICU stay’ in critically unwell patients with acute pancreatitis: insights from a 2003–2020 cohort analysis using the ANZICS-CORE database', Critical Care, 29,

Journal articles | 2025

Wu L; Carlino MS; Brown DA; Long GV; Clifton-Bligh R; Mellor R; Moore K; Sasson SC; Menzies AM; Tsang V; Gunton JE, 2025, 'Response to Letter to the Editor from Hao and Xue: “Checkpoint Inhibitor-associated Autoimmune Diabetes Mellitus Is Characterized by C-Peptide Loss and Pancreatic Atrophy”', Journal of Clinical Endocrinology and Metabolism, 110, pp. e552 - e553,

Journal articles | 2025

Wui S; Hewavisenti RV; Rabiei M; Kelleher A; Rajendra S; Sasson SC, 2025, 'Multiplex immunofluorescence reveals immune-suppressed tumour microenvironment in HPV-negative oesophageal adenocarcinoma', Pathology, 57, pp. S92 - S92,

Journal articles | 2025

Wui S; Hewavisenti RV; Rabiei M; Kelleher AD; Farzin M; Rajendra S; Sasson SC, 2025, 'HPV status shapes T-cell immunoprofiles in oesophageal adenocarcinoma: high regulatory T cell infiltration predicts poor prognosis', Journal of Translational Medicine, 24, pp. 12 - 12,

Journal articles | 2024

Gupta T; Antanaviciute A; Hyun-Jung Lee C; Ottakandathil Babu R; Aulicino A; Christoforidou Z; Siejka-Zielinska P; O'Brien-Ball C; Chen H; Fawkner-Corbett D; Geros AS; Bridges E; McGregor C; Cianci N; Fryer E; Alham NK; Jagielowicz M; Santos AM; Fellermeyer M; Davis SJ; Parikh K; Cheung V; Al-Hillawi L; Sasson S; Slevin S; Brain O; Bird-Lieberman E; Fourie S; Johnston R; Joshi H; Mujamdar D; Panter S; Patodi N; Shaji S; Tidbury J; Verma A; Fernandes RA; Koohy H; Simmons A, 2024, 'Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis', Cancer Cell, 42, pp. 797 - 814.e15,

Journal articles | 2024

Hastak P; Cromer D; Malycha J; Andersen CR; Raith E; Davenport MP; Plummer M; Sasson SC, 2024, 'Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia', Scientific Reports, 14, pp. 11102,

Journal articles | 2024

Revoltar M; van der Linde R; Cromer D; Gatt PN; Smith S; Fernandez MA; Vaughan L; Blyth E; Curnow J; Tegg E; Brown DA; Sasson SC, 2024, 'Indeterminate measurable residual disease by multiparameter flow cytometry is associated with an intermediate risk of clinical relapse in adult patients with acute leukaemia', Pathology, 56, pp. 882 - 888,

Journal articles | 2024

Wu L; Carlino MS; Brown DA; Long GV; Clifton-Bligh R; Mellor R; Moore K; Sasson SC; Menzies AM; Tsang V; Gunton JE, 2024, 'Checkpoint Inhibitor-Associated Autoimmune Diabetes Mellitus Is Characterized by C-peptide Loss and Pancreatic Atrophy', Journal of Clinical Endocrinology and Metabolism, 109, pp. 1301 - 1307,

Journal articles | 2024

Wu L; Wentworth J; Liddle C; Carlino M; Brown D; Clifton-Bligh RJ; Long G; Sasson S; Tsang V; Menzies A; Gunton JE, 2024, '7760 Identifying Conventional and Novel Biomarkers to Predict Checkpoint Inhibitor Associated Autoimmune Diabetes', Journal of the Endocrine Society, 8,

Journal articles | 2024

van der Linde R; Gatt PN; Smith S; Fernandez MA; Vaughan L; Blyth E; Curnow J; Brown DA; Tegg E; Sasson SC, 2024, 'CORRELATION OF FLOW CYTOMETRIC MEASURABLE RESIDUAL DISEASE (FC-MRD) WITH MOLECULAR MRD AND CLINICAL OUTCOME AT ONE YEAR IN ADULT B-ACUTE LYMPHOBLASTIC LEUKAEMIA (B-ALL) AND ACUTE MYELOID LEUKAEMIA (AML)', INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 46, pp. 108 - 108

Journal articles | 2023

Barreto SG; Kaambwa B; Venkatesh K; Sasson SC; Andersen C; Delaney A; Bihari S; Pilcher D, 2023, 'Mortality and costs related to severe acute pancreatitis in the intensive care units of Australia and New Zealand (ANZ), 2003–2020', Pancreatology, 23, pp. 341 - 349,

Journal articles | 2023

Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Klemm V; Munier CML; Hoppe AC; Tea F; Pillay A; Stella AO; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J; Carey Hoppe A, 2023, 'Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses', American Journal of Hematology, 98, pp. 131 - 139,

Journal articles | 2023

Cromer D; Steain M; Reynaldi A; Schlub TE; Khan SR; Sasson SC; Kent SJ; Khoury DS; Davenport MP, 2023, 'Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis', Nature Communications, 14, pp. 1633,

Journal articles | 2023

Dharan NJ; Sasson SC; Ahlenstiel G; Andersen CR; Bloch M; Buckland G; Hamad N; Han WM; Kelleher AD; Long GV; Matthews GV; Mina MM; Papot E; Petoumenos K; Swaminathan S; Withers B; Yun J; Polizzotto MN, 2023, 'Clinical and laboratory features of COVID-19 illness and outcomes in immunocompromised individuals during the first pandemic wave in Sydney, Australia', Plos One, 18,

Journal articles | 2023

Finfer S; Venkatesh B; Hotchkiss RS; Sasson SC, 2023, 'Lymphopenia in sepsis—an acquired immunodeficiency?', Immunology and Cell Biology, 101, pp. 535 - 544,

Journal articles | 2023

Gupta M; Balachandran H; Louie RHY; Li H; Agapiou D; Keoshkerian E; Christ D; Rawlinson W; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Bartlett AW; Sasson SC; Ahlenstiel G; Dwyer D; Lloyd AR; Martinello M; Luciani F; Bull RA, 2023, 'High activation levels maintained in receptor-binding domain–specific memory B cells in people with severe coronavirus disease 2019', Immunology and Cell Biology, 101, pp. 142 - 155,

Journal articles | 2023

Hewavisenti RV; Arena J; Ahlenstiel CL; Sasson SC, 2023, 'Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated cancer risk', Frontiers in Immunology, 14,

Journal articles | 2023

Rankin K; Hastak P; Wong A; Sasson SC; Beaton B; Yeola A; Warden A; Turville S; Kelleher AD; Brilot F; Trotman J, 2023, 'Immune response to COVID‐19 vaccination in patients with Waldenström macroglobulinaemia who pause their BTKi therapy', eJHaem, 4, pp. 728 - 732,

Journal articles | 2023

Reardon B; Smith S; Van Der Linde R; Sasson SC, 2023, 'Use of anti-JOVI.1 antibodies to detect clonal T cell populations: implementation into a diagnostic flow cytometry laboratory and correlation with clinical findings', Pathology, 55, pp. S23 - S23,

Journal articles | 2023

Venkatesh K; Glenn H; Delaney A; Andersen CR; Sasson SC, 2023, 'Fire in the belly: A scoping review of the immunopathological mechanisms of acute pancreatitis', Frontiers in Immunology, 13,

Journal articles | 2023

Wu L; Tsang V; Menzies AM; Sasson SC; Carlino MS; Brown DA; Clifton-Bligh R; Gunton JE, 2023, 'Risk Factors and Characteristics of Checkpoint Inhibitor– Associated Autoimmune Diabetes Mellitus (CIADM): A Systematic Review and Delineation From Type 1 Diabetes', Diabetes Care, 46, pp. 1292 - 1299,

Journal articles | 2023

van der Linde R; Gatt PN; Smith S; Fernandez MA; Vaughan L; Blyth E; Curnow J; Brown DA; Tegg E; Sasson SC, 2023, 'Measurable Residual Disease (MRD) by Flow Cytometry in Adult B-Acute Lymphoblastic Leukaemia (B-ALL) and Acute Myeloid Leukaemia (AML): Correlation with Molecular MRD Testing and Clinical Outcome at One Year', Cancers, 15,

Journal articles | 2023

van der Linde R; Smith S; Brown DA; Sasson SC; Tegg E, 2023, 'Measurable residual disease in adult acute myeloid leukaemia: evaluation of a multidimensional ‘radar’ flow cytometric plot analysis method', Pathology, 55, pp. 383 - 390,

Journal articles | 2022

Adhikari A; Abayasingam A; Rodrigo C; Agapiou D; Pandzic E; Brasher NA; Fernando BSM; Keoshkerian E; Li H; Kim HN; Lord M; Popovic G; Rawlinson W; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Grubor-Bauk B; Lloyd AR; Martinello M; Bull RA; Tedla N; Kaldor J; Dore G; Sorrell T; Bartlett A; Lemberg D; Di Girolamo N; Byrne M; Hammoud M; Sultan R; Konecny P; Matthews G; Shek D; Holdaway S; Mitsa-Kos K; How-Chow D; Lagunday R; Robinson S; Terrill L; Joshi N; Li Y; Gill S; Sevehon A, 2022, 'Longitudinal Characterization of Phagocytic and Neutralization Functions of Anti-Spike Antibodies in Plasma of Patients after Severe Acute Respiratory Syndrome Coronavirus 2 Infection', Journal of Immunology, 209, pp. 1499 - 1512,

Journal articles | 2022

Balachandran H; Phetsouphanh C; Agapiou D; Adhikari A; Rodrigo C; Hammoud M; Shrestha LB; Keoshkerian E; Gupta M; Turville S; Christ D; King C; Sasson SC; Bartlett A; Grubor-Bauk B; Rawlinson W; Aggarwal A; Stella AO; Klemm V; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Dwyer DE; Sorrell TC; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2022, 'Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses', Cell Reports, 38, pp. 110345,

Journal articles | 2022

Hastak PS; Andersen CR; Kelleher AD; Sasson SC, 2022, 'Frontline workers: Mediators of mucosal immunity in community acquired pneumonia and COVID-19', Frontiers in Immunology, 13,

Journal articles | 2022

Kent SJ; Khoury DS; Reynaldi A; Juno JA; Wheatley AK; Stadler E; John Wherry E; Triccas J; Sasson SC; Cromer D; Davenport MP, 2022, 'Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?', Nature Reviews Immunology, 22, pp. 387 - 397,

Journal articles | 2022

Rankin K; Beaton B; Sasson S; Raedemaecker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Patel M; Klemm V; Munier CML; Carey Hoppe A; Tea F; Pillay A; Ospina A; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J, 2022, 'PB2087: EFFICACY OF A 3RD COVID VACCINE, INCLUDING DURING A BTKI PAUSE, IN INDIVIDUALS WITH WALDENSTRÖM MACROGLOBULINEMIA AND FOLLICULAR LYMPHOMA', HemaSphere, 6, pp. 1958 - 1959,

Journal articles | 2021

Abayasingam A; Balachandran H; Agapiou D; Hammoud M; Rodrigo C; Keoshkerian E; Li H; Brasher NA; Christ D; Rouet R; Burnet D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Stella AO; Fichter C; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Tea F; Pilli D; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA; Burnett D, 2021, 'Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, 2, pp. 100228,

Journal articles | 2021

Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Warden A; Stella AO; Aggarwal A; Caterson ID; Phetsouphanh C; Turville S; Kelleher AD; Brilot F; Trotman J, 2021, 'Efficacy of Vaccine BNT162b2 (Pfizer-BioNTech) in Individuals with Waldenstrom's Macroglobulinemia and Follicular Lymphoma in Australia', BLOOD, 138,

Journal articles | 2021

Hargreaves CE; Salatino S; Sasson SC; Charlesworth JEG; Bateman E; Patel AM; Anzilotti C; Broxholme J; Knight JC; Patel SY, 2021, 'Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders', Journal of Clinical Immunology, 41, pp. 1315 - 1330,

Journal articles | 2021

Sasson SC; Slevin SM; Cheung VTF; Nassiri I; Olsson-Brown A; Fryer E; Ferreira RC; Trzupek D; Gupta T; Al-Hillawi L; Issaias ML; Easton A; Campo L; FitzPatrick MEB; Adams J; Chitnis M; Protheroe A; Tuthill M; Coupe N; Simmons A; Payne M; Middleton MR; Travis SPL; Fairfax BP; Klenerman P; Brain O, 2021, 'Interferon-Gamma–Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis', Gastroenterology, 161, pp. 1229 - 1244.e9,

Journal articles | 2021

Sasson SC; Wilkins LE; Watson RA; Jolly C; Brain O; Klenerman P; Olsson-Brown A; Fairfax BP, 2021, 'Identification of neutralising pembrolizumab anti-drug antibodies in patients with melanoma', Scientific Reports, 11,

Journal articles | 2021

Sasson SC, 2021, 'Autoimmune toxicities of T cell checkpoint inhibitors', Pathology, 53, pp. S16 - S16,

Journal articles | 2021

Wu L; Tsang VHM; Sasson SC; Menzies AM; Carlino MS; Brown DA; Clifton-Bligh R; Gunton JE, 2021, 'Unravelling Checkpoint Inhibitor Associated Autoimmune Diabetes: From Bench to Bedside', Frontiers in Endocrinology, 12,

Journal articles | 2021

van der Linde R; Smith S; Sasson SC; Brown D; Tegg E, 2021, 'Use of multidimentional flow cytometry plots to improve measurable residual disease monitoring of acute myeloid leukaemias', Pathology, 53, pp. S46 - S46,

Journal articles | 2020

Cheung VT; Gupta T; Olsson-Brown AC; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes-Bellido E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Su1185 IMMUNE CHECKPOINT INHIBITOR-RELATED COLITIS ASSESSMENT AND PROGNOSIS: CAN UCEIS, MAYO AND NANCY INDEX SCORING POINT THE WAY?', Gastroenterology, 158,

Journal articles | 2020

Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'P272 Immune checkpoint inhibitor-related colitis assessment and prognosis: can inflammatory bowel disease scoring point the way?', Journal of Crohn's and Colitis, 14, pp. S286 - S288,

Journal articles | 2020

Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Tuthill M; Protheroe AS; Chitnis M; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?', British Journal of Cancer, 123, pp. 207 - 215,

Journal articles | 2020

Sasson SC; Gordon CL; Christo SN; Klenerman P; Mackay LK, 2020, 'Local heroes or villains: tissue-resident memory T cells in human health and disease', Cellular and Molecular Immunology, 17, pp. 113 - 122,

Journal articles | 2020

Sasson SC; Zaunders JJ; Nahar K; Munier CML; Fairfax BP; Olsson-Brown A; Jolly C; Read SA; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Payne MJ; Cheung VTF; Gupta T; Klenerman P; Long GV; Brain O; Menzies AM; Kelleher AD, 2020, 'Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulcerative colitis', Clinical and Experimental Immunology, 202, pp. 335 - 352,

Journal articles | 2019

Sasson SC; Cheung VTF; Gupta T; Zaunders JJ; Nahar K; Munier CM-L; Olsson-Brown A; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Long GV; Menzies AM; Kelleher A; Payne M; Fairfax B; Middleton MR; Klenerman P; Brain O, 2019, '1303P Tissue-based activation of mucosal-associated invariant T (MAIT) cells in combination ipilimumab and nivolumab checkpoint inhibitor (CI) colitis', Annals of Oncology, 30, pp. v530,

Journal articles | 2019

Sasson SC; Corbett A; McLachlan AJ; Chen R; Adelstein SA; Riminton S; Limaye S, 2019, 'Enhanced serum immunoglobulin G clearance in myotonic dystrophy-associated hypogammaglobulinemia: A case series and review of the literature', Journal of Medical Case Reports, 13, pp. 338,

Journal articles | 2018

Deenick EK; Morey A; Danta M; Emmett L; Fay K; Gracie G; Ma CS; Macintosh R; Smith SABC; Sasson SC; Sewell WA; Cowley M; Tangye SG; Kelleher AD; Phan TG, 2018, 'Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency', Journal of Clinical Immunology, 38, pp. 159 - 162,

Journal articles | 2017

Koelsch KK; Rasmussen TA; Hey-Nguyen WJ; Pearson C; Xu Y; Bailey M; Marks KH; Sasson SC; Taylor MS; Tantau R; Obeid S; Milner B; Morrissey O; Pinto AN; Suzuki K; Busch MP; Keating SM; Kaiser P; Yukl S; Wong JK; Hiener BM; Palmer S; Zaunders J; Post JJ; Chan DJ; Avery S; Milliken ST; Kelleher AD; Lewin SR; Cooper DA; Cooper D, 2017, 'Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals', Journal of Acquired Immune Deficiency Syndromes, 75, pp. 328 - 337,

Journal articles | 2017

Sasson SC; Russo R; Chung T; Chu G; Hunyor I; Williamson J; Murad A; Kane A; Riminton S; Limaye S, 2017, 'Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by ¹⁸F-fluorodeoxyglucose-positron emission tomography: Two case reports and a review of the literature', Journal of Medical Case Reports, 11,

Journal articles | 2016

Anderson S; Sasson SC; Lee FJ; Cooper W; Larsen S; Garsia R, 2016, 'Episodic fevers and vasodilatory shock mimicking urosepsis in a patient with HIV-associated multicentric Castleman's Disease: A case report', BMC Infectious Diseases, 16, pp. 53,

Journal articles | 2016

Sasson SC; Davies S; Chan R; Davies L; Garsia R, 2016, 'Cerebral toxoplasmosis in a patient with myasthenia gravis and thymoma with immunodeficiency/Good's syndrome: A case report', BMC Infectious Diseases, 16, pp. 457,

Journal articles | 2015

Koelsch KK; Hey-Cunningham WJ; Sasson SC; Pearson C; Bailey M; Marks KH; Hiener BM; Palmer S; Zaunders JJ; Post JJ; Milliken ST; Kelleher AD; Cooper DA; Xu Y, 2015, 'Allogeneic bone marrow transplantation in two HIV-1 infected patients shows no detectable HIV-1 RNA or DNA, and a profound reduction in HIV-1 antibodies', Pathology, 47, pp. S55 - S55,

Journal articles | 2015

Sasson SC; McGill K; Wienholt L; Carr A; Brown D; Kelleher AD; Breit SN; Sewell WA, 2015, 'Retrospective audit of the freeliteTM serum free light chain (SFLC) assay: testing patterns, concordance with serum and urine electrophoresis/immunofixation and correlation with the N latex FLC assay', Pathology, 47, pp. S94 - S94,

Journal articles | 2015

Sasson SC; McGill K; Wienholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay', Pathology, 47, pp. 564 - 569,

Journal articles | 2015

Sasson SC; Smith SA; Qiu MR; Stone ECA; Sewell WA, 2015, 'Monoclonal precursor T-cell infiltrate in recurrent thymoma: a case report', Pathology, 47, pp. 375 - 377,

Journal articles | 2014

Sasson S; Smith S; Sewell WA; Morey A; Danta M; Emmett L; Kelleher AD; Fay K; Phan T, 2014, 'MONOCLONAL B-CELL POPULATION OF INDETERMINANT MALIGNANT POTENTIAL IN THE SETTING OF ATYPICAL CVID ASSOCIATED WITH LYMPHADENOPATHY AND SPLENOMEGALY', INTERNAL MEDICINE JOURNAL, 44, pp. 33 - 33,

Journal articles | 2014

Sasson SC; Kelleher AD, 2014, 'Site-specific host gene modification by zinc finger nucleases: pointing the way to drug free control of HIV-1?', Clinical and Translational Immunology, 3, pp. e19,

Journal articles | 2013

Sasson SC; Oon A; Chagantri J; Brew BJ; Carr A, 2013, 'Posterior reversible encephalopathy syndrome (PRES) in an HIV-1 infected patient with disseminated varicella zoster virus: a case report', BMC Infectious Diseases, 13, pp. 396 - 396,

Journal articles | 2012

Sasson SC; Zaunders J; Seddiki N; Mcbride K; Koelsch KK; Merlin KM; Smith DE; Cooper DA; Kelleher AD; Bailey MR, 2012, 'Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection', PLoS One, 7, pp. e31148,

Journal articles | 2009

Seddiki N; Sasson SC; Santner-Nanan B; Munier M; Van Bockel DJ; Ip S; Marriott D; Pett SL; Nanan R; Cooper DA; Zaunders J; Kelleher AD, 2009, 'Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease', European Journal of Immunology, 39, pp. 391 - 403,

Journal articles | 2006

Fazekos de St Groth B; Seddiki N; Santner-Nanan B; Martinson J; Zaunders J; Sasson SC; Landay A; Nanan R; Kelleher AD, 2006, 'Expression of IL-2 and IL-7 receptors discriminates between human regulatory and activated T-cells within CD45RA and CD45RO compartments', Clinical Immunology, 119, pp. S7 - S7

Journal articles | 2006

Sasson SC; Zaunders J; Kelleher AD, 2006, 'The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostatis and the challenges facing its utilization as a novel therapy. 2006;7:1571-1582.', Current Drug Targets, 7, pp. 1571 - 1582

Journal articles | 2006

Sasson SC; Zaunders J; Zanetti G; King E; Merlin K; Smith DE; Stanley K; Cooper DA; Kelleher AD, 2006, 'Increased plasma interleukin-7 level correlates with decreased CD127 and increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection', Journal of Infectious Diseases, 193, pp. 505 - 514

Journal articles | 2006

Seddiki N; Santner-Nanan B; Martinson J; Zaunders J; Sasson SC; Landay A; Solomon MJ; Selby W; Alexander S; Nanan R; Kelleher AD; Fazekas de St Groth B; Solomon M, 2006, 'Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells', Journal of Experimental Medicine, 203, pp. 1693 - 1700,

Journal articles | 2006

Zaunders J; Ip S; Munier CM; Munier M; Kaufmann D; Suzuki K; Brereton C; Seddiki N; Sasson SC; Koelsch KK; Landay A; Grey PA; Finlayson R; Kaldor JM; Rosenberg E; Walker BD; Fazekas de St Groth B; Cooper DA; Kelleher AD, 2006, 'Infection of CD127(+) (Interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection', Journal of Virology, 80, pp. 10162 - 10172

Journal articles | 2005

Sasson SC; Kelleher AD; Cooper DA, 2005, 'The modern ART of HIV infection management: Towards a tailored approach to maximize CD4 T cell reconstitution', Clinical Infectious Diseases, 41, pp. 373 - 375
Preprints | 2024

Reardon B; Hsu J; Smith S; van der Linde R; Brown DA; Tegg E; Sasson SC, 2024, Anti-JOVI.1 antibody to detect clonal T cell populations: implementation into a diagnostic flow cytometry laboratory and correlation with clinical findings,

Preprints | 2023

Dharan N; Sasson S; Ahlenstiel G; Andersen C; Bloch M; Buckland G; Hamad N; Han WM; Kelleher A; Long G; Matthews G; Mina M; Papot E; Petoumenos K; Swaminathan S; Withers B; Yun J; Polizzotto M, 2023, Clinical and laboratory features of COVID-19 illness and outcomes in immunocompromised individuals during the first pandemic wave in Sydney, Australia,

Preprints | 2022

Cromer D; Steain M; Reynaldi A; Schlub T; Sasson S; Kent S; Khoury D; Davenport MP, 2022, Neutralising antibodies predict protection from severe COVID-19,

Conference Papers | 2021

Cheung V; Sasson S; Misheva M; Slevin S; Gupta T; Webb G; Walsh A; Simmons A; Quraishi N; Iqbal T; Middleton M; Fairfax B; Payne M; McCullagh J; Klenerman P; Brain O, 2021, 'P93 Faecal microbiota transplant for refractory checkpoint inhibitor immunotherapy-related colitis', in Posters, BMJ Publishing Group Ltd and British Society of Gastroenterology, pp. A89.1 - A89, presented at Abstracts of the BSG Campus, 21–29 January 2021,

Conference Abstracts | 2020

Cheung VT; Gupta T; Olsson-Brown AC; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes-Bellido E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'IMMUNE CHECKPOINT INHIBITOR-RELATED COLITIS ASSESSMENT AND PROGNOSIS: CAN UCEIS, MAYO AND NANCY INDEX SCORING POINT THE WAY?', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, TX, Austin, Vol. 158, pp. S535 - S536, presented at Crohn's and Colitis Congress, TX, Austin, 23 January 2020 - 25 January 2020,

Conference Abstracts | 2020

Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Immune checkpoint inhibitor-related colitis assessment and prognosis: can inflammatory bowel disease scoring point the way?', in JOURNAL OF CROHNS & COLITIS, OXFORD UNIV PRESS, Vol. 14, pp. S286 - S288,

Conference Abstracts | 2019

Sasson SC; Cheung VTF; Gupta T; Zaunders JJ; Nahar K; Munier CM-L; Olsson-Brown A; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Long GV; Menzies AM; Kelleher A; Payne M; Fairfax B; Middleton MR; Klenerman P; Brain O, 2019, 'Tissue-based activation of mucosal-associated invariant T (MAIT) cells in combination ipilimumab and nivolumab checkpoint inhibitor (CI) colitis', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, SPAIN, Barcelona, Vol. 30, pp. 530 - 530, presented at 44th Congress of the European-Society-for-Medical-Oncology (ESMO), SPAIN, Barcelona, 27 September 2019 - 01 October 2019,

Conference Abstracts | 2019

Sasson SC; Zaunders J; Nahar K; Munier C; Read SA; Ahlensteil G; Palendira U; Scolyer RA; Carlino M; Long GV; Menzies AM; Kelleher AD, 2019, 'Characterisation of peripheral blood mononuclear cells in patients with combination ipilimumab and nivolumab therapy-related colitis', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, AUSTRIA, Vienna, Vol. 110, pp. S21 - S22, presented at 6tth International Cancer Immunotherapy Conference in Europe (ITOC), AUSTRIA, Vienna, 11 April 2019 - 13 April 2019,

Conference Abstracts | 2015

Sasson SC; Davies S; Chan R; Davies L; Garsia R, 2015, 'IN GOOD CONSCIENCE', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, Vol. 45, pp. 28 - 28,

Conference Abstracts | 2015

Sasson SC; McGill K; Weinholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'COMPARISON OF THE FREELITE (TM) SERUM FREE LIGHT CHAIN (SFLC) ASSAY WITH SERUM AND URINE ELECTROPHORESIS/IMMUNOFIXATION AND THE N LATEX FLC ASSAY', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, Vol. 45, pp. 24 - 24,

2025-2029 NHMRC Clinical Trials and Cohort grant for Corticosteroids in Septic Shock "CREST" Randomised ControlledTrial (CID)

2025-2029 MRFF for FludrocortIsoNE in septic shock Evaluation" The "FINESSE" Adaptive randomised clinical trial (CID)

2024-2027 91ɫ��Ƭ Scientia Fellowship (Renewed)

2022-2026 MRFF for Comparing Immunisation-boosting Regimens for COVID-19 for people Upon Initiation of immunosuppressive Therapies ("CIRCUIT" RCT) (CIA)

2022-2026 MRFF for Comparing Use of B cell depletion therapies to IVIg in CIDP ("CUBIC" Study) (CIG)

2022-2023 NSW Health Pathology Grant for Critical Illness, Infection and Immunology "CI3" Biobank

2021-22�� NIH R21 Co-infection and Cancer

2020-23 91ɫ��Ƭ Scientia Fellowship

2020�� Kirby Institute Emerging Investigator Award

2020�� Australian Intensive Care Foundation Grant

2019�� University of Oxford Human Immunology Discovery Initiative Grant

2019�� University of Oxford Medical Sciences Division Pump-Prime Grant

2019�� Nanostring Autoimmunity Grant

2018-19��Oxford-Celgene Postdoctoral Fellowship

2013�� SydPath Research Grant

2006�� NHMRC Dora Lush (Biomedical) PhD Scholarship

2004�� St Vincent's Hospital Centre for Immunology PhD Scholarship

��

"What's the Difference between a Tumour and a Cancer?"�� (2025)

91ɫ��Ƭ Triple I Interview "Immunity in unexpected places"—(2025)

Dr Sarah Sasson appointed Head of Immunovirology and Pathogenesis Program at The Kirby Institute—��(2025)

Alum, immunologist and debut novelist— (2024)

Rising rates of Pregnancy-associated Cancer— (2024)

$2.75M MRFF funding for CIRCUIT Study RCT—(2022)

"First Cancer Immunology Ideas Forum Takes place at 91ɫ��Ƭ"—��(2021)

"Immunocompromised: The forgotten people"—��(2021)

COVID-19 Outcomes Registry Study for Immunosuppressed Patients in Australia (CORIA) Study—��(2020)

My Research Supervision

Joshua Arena (PhD Student)
Phoebe Crammond (PhD Student)
Pamela Karas (PhD Student)
Tyler Shai-Hee (PhD Student)
Karthik Venkatesh (PhD Student)
Zong-Hong Zhang (PhD Student)

��

PhD Students (Completed)

Dr Linda Wu (University of Sydney) 2025

��

Honours Students (Completed)

Maya Andersen��2025
Philip Chen 2025
Phoebe Crammond 2024
Subin Wui 2024
Hazel Khosbayer 2023
Aayushma Lohani 2023
Richard Zelei 2020

91ɫ��Ƭ

Follow

Dr Sarah Sasson

Follow me