Dr Krista Siefried
RN;听BSc; GCert Continuing Care;听GDip Coronary Care;听PhD
Clinical Research Lead and Deputy Director, the National Centre for Clinical Research on听Emerging Drugs (NCCRED). Senior Lecturer, 91色情片 National Drug and Alcohol Research Centre (NDARC), and St Vincent's Hospital Sydney Alcohol and Drug Service.
Dr Siefried is a leader in clinical research and clinical trials in populations at risk of harms due to substance use disorders. In her role as Clinical Research Lead and Deputy Director at NCCRED her听extensive HIV, Infectious Diseases, Drug and Alcohol, and Public Health experience enable her听to direct a program of clinical research and translation; facilitate the establishment of听a national clinical research network; and oversee the NCCRED clinical research capacity building grants, seed funding grants, and clinical research fellowships and scholarships.听
Dr Siefried has extensive experience in clinical research, healthcare, and clinical project management. Her broad clinical research interests include pharmacotherapies, comorbidities and treatment outcomes in people living with methamphetamine dependence.
- Publications
- Media
- Grants
- Awards
- Research Activities
- Engagement
- Teaching and Supervision
NHMRC: $8,133,073
Other Public and Industry: $23,496,857
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2026: National Drug and Alcohol Research Centre Ian Webster Award -听Faculty of Medicine, 91色情片
2024: Transform the System: Global Impact (awarded for the OLAM: Trial of lisdexamfetamine for methamphetamine withdrawal team) -听St Vincent's Health Australia
2022: National Drug and Alcohol Research Centre听Prof Richard Mattick Award -听Faculty of Medicine, 91色情片
2016: Nursing Excellence Award听-听Clinical Researcher on St Vincent鈥檚 Campus -听St Vincent鈥檚 Clinic Foundation听
2013-2014听Fellowship: Awarded for research on factors associated with suboptimal outcomes in antiretroviral therapy (CIA) -听Gilead
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Current research:
S-Check 2.0 cohort study: A smartphone application for methamphetamine use (open to recruitment, info )
A randomised controlled trial of lisdexamfetamine versus placebo, for the treatment of acute methamphetamine withdrawal (the OLAM trial) (open to recruitment, info )
A study examining a new internet delivered cognitive behavioural therapy program for methamphetamine (the IMPACT study) (open to recruitment, info )
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- Established the National Methamphetamine and Emerging Drugs Clinical Research Network Working Group, engaging multi-disciplinary stakeholders to collaborate towards multi-centre clinical research
- Developed, implemented and oversee the NCCRED seed funding grants, awarding over $2.7M in competitive funding over four rounds
- Developed, implemented and oversee the NCCRED clinical research fellowships and scholarships programs, supporting 6听AOD clinical scholars to conduct research and contribute to 91色情片 through their adjunct positions
- Active member of the:
- St Vincent鈥檚 Hospital Alcohol and Drug Service Research Committee
- NDARC Strategic Advisory Committee
- St Vincent鈥檚 Health Sydney Inclusive Health Committee
My Research Supervision
Current - PhD
Craig Rodgers - Feasibility, safety and cost of time-limited parenteral hydromorphone in people with treatment-resistant injecting opioid use disorder (Primary Supervisor. Secondary Supervisor: Prof Greg Dore)
Stassi Kypri - Is an anecdotal reporting system for emerging drug-related concerns a useful, acceptable tool for users, and a reliable source of data that can be utilised to enhance drug monitoring and early warning systems in Australia? (Secondary Supervisor. Joint Primary Supervisors: Dr Jack Freestone, Prof Nadine Ezard)
Dora Karavasilis - Digitally delivered psychosocial support for people who use methamphetamine. (Secondary Supervisor. Primary Supervisor: Dr Kathryn Fletcher)
Completed - PhD
Liam Acheson - Pharmacotherapy for adults during听acute withdrawal from methamphetamine (Primary Supervisor. Co-Supervisors:听Prof Michael Farrell, A/Prof Rebecca McKetin, Conjoint Prof Nadine Ezard)
Jack Freestone - Exploring and Implementing Community-Led Chemsex Interventions for Gay and Bisexual Men who have sex with Men (Joint Primary Supervisor with听Dr Mohamed Hammoud. Co-Supervisors: Prof Garrett Prestage, Dr Adam Bourne)
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My Teaching
Ongoing
Andrea Delgado (91色情片 MIPH Scholarly Project): An Australian cohort of people using the S-Check App to track their methamphetamine use
Terrence Truong (91色情片 Medicine Hons): Methamphetamine associated psychosis: a qualitative study.
Alex Fowler (Notre Dame Year 2 Research Project): Psilocybin and methamphetamine induced psychosis
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Completed -听91色情片 Medicine Hons Project
Sophie van der Helder (First Class Hons) - 听(Co-supervised with A/Prof Jonathan Brett) (2023)
Vincent Chauvet (Hons) - Outcomes and measures used in research of psychedelic medications for mental health and addiction (Co-supervised with A/Prof Jonathan Brett) (2023)
Keaton Buhagiar (First Class Hons) - (Co-supervised with A/Prof Jonathan Brett) (2022)
Oliver Harris (First Class Hons) - (Co-supervised with A/Prof Jonathan Brett) (2021)
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Completed - Notre Dame Medicine Year 2 Research Project
Rhiannon Lindsey -听(Co-supervised with A/Prof Jonathan Brett) (2022)
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Completed - 91色情片 Medicine Year 4 Research Project
Mohamed Budebes - A quantitative study of the experience of GHB consumption, GHB-related harms, and harm reduction practices (Co-Supervised with Dr Brendan Clifford; Winner: Best ECR Poster at APSAD 2024) (2024)
Amy Healey - (Co-supervised听with A/Prof Jonathan Brett) (2020)
Angus Tolhurst-McKiernan听- Methamphetamine use and its associations with insomnia and psychosis (Co-supervised with Prof Nadine Ezard and A/Prof Jonathan Brett) (2019)听
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Clinical
Nursing preceptorships; Clinical Psychology Students (research supervision and clinical supervision); Nursing student supervision (clinical)