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Professor Joseph Powell

Professor
Medicine & Health
School of Biomedical Sciences
  • Journal articles | 2026
    Cartland S; Kelland E; Le N; Stanley C; Menezes R; Murphy M; Ku J; Boccanfuso L; Sandeman L; Beattie L; Turner L; Tumanov S; Nedoboy P; Dona M; Powell J; Thomas S; Bursill C; Pinto A; Aitken S; Robinson D; Kavurma M, 2026, 'Abstract We0077: Females exhibit greater mitochondrial endothelial dysfunction, impairing vascular healing in diabetes-associated peripheral artery disease', JVS-Vascular Science, pp. 100380 - 100380,
    Journal articles | 2026
    Idrees S; Chen H; Sadaf T; Rehman SF; Johansen MD; Paudel KR; Liu G; Wang Y; Luecken MD; Hortle E; Philp AS; Budden KF; O鈥檙ourke M; Kaiko GE; Lucas SEM; Dickinson JL; Allen PC; Powell JE; Zhang LY; Chambers DC; Corte T; Caramori G; Sauler M; Wark PA; Gote-Schniering J; Lehmann M; Conlon TM; Kapellos TS; Yildirim A脰; Faner R; Dharmage SC; Wheelock CE; van den Berge M; Nawijn MC; Polverino F; Belz GT; Chotirmall SH; Segal LN; Faiz A; Hansbro PM, 2026, 'Multi-omics to study chronic respiratory diseases and viral infections', European Respiratory Review, 35,
    Journal articles | 2026
    Lee KJ; Kao YC; Jiang A; Prokofyeva A; Tom LN; Jagirdar K; Smit DJ; Oey HM; Tan JM; Ainger SA; Huang N; Tuong ZK; Andersen S; Senabouth A; Powell JE; Lambie D; Schaider H; Soyer HP; Sturm RA; Welm AL; Grossman D; Judson-Torres RL; Stark MS, 2026, 'Subclinical fields of BRAF V600E-mutant melanocytes populate human skin and are enriched around melanoma and naevi', British Journal of Dermatology, 194, pp. 301 - 310,
    Journal articles | 2026
    Lee WE; Henry A; Spenceley ER; Sagi-Zsigmond E; Bowen B; Nguyen TV; Gray MP; Grieve SM; Powell JE; Figtree GA, 2026, 'Increased mROS Generation Associates With Cardiovascular Risk in BioHEART-CT PBMCs', Clinical and Translational Science, 19,
    Journal articles | 2026
    Maksimovic J; Shanthikumar S; Howitt G; Dixit G; Hickey PF; Anttila C; Brown DV; Gubbels L; Senabouth A; Amann-Zalcenstein D; Powell JE; Ranganathan SC; Oshlack A; Neeland MR, 2026, 'Single-cell profiling of BAL in preschool cystic fibrosis reveals macrophage dysregulation and ivacaftor-modified inflammatory programs in the early life lung.', Mucosal Immunol,
    Journal articles | 2026
    Powell JE, 2026, 'Charting immune variation through genetics and single-cell genomics', Gigascience, 15,
    Journal articles | 2026
    Sopena-Rios M; Ripoll-Cladellas A; Omidi F; Ballouz S; Alquicira-Hernandez J; Oelen R; Hewitt AW; Franke L; van der Wijst MGP; Powell JE; Mel茅 M, 2026, 'Single-cell analysis of the human immune system reveals sex-specific dynamics of immunosenescence', Nature Aging,
    Journal articles | 2026
    Wilson SB; Vanslambrouck JM; Murphy A; Neavin DR; Powell JE; Howden SE; Little MH, 2026, 'Classification of indeterminate and off-target cell types within human kidney organoid differentiation', iScience, pp. 115752 - 115752,
    Journal articles | 2026
    Zhou Y; Sumner S; Adeluwa T; Zhu L; Salazar-Maga帽a S; Kim H; Gona S; Nyasimi F; Kulkarni R; Powell J; Madduri R; Liu B; Chen M; Im HK, 2026, 'Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework', STAR Protocols, 7,
    Journal articles | 2025
    Atkeson T; Wilson SB; Ruiz-Morales ER; Little MH; Vento-Tormo R; Neavin D; Powell JE, 2025, 'A novel paradigm for single-cell annotation in stem cell research', Stem Cell Reports, 20,
    Journal articles | 2025
    Cartland S; Kelland E; Le N; Stanley C; Menezes R; Murphy M; Ku J; Boccanfuso L; Sandeman L; Beattie L; Turner L; Tumanov S; Nedoboy P; Dona M; Powell J; Thomas S; Bursill C; Pinto A; Aitken S; Robinson D; Kavurma M, 2025, 'Abstract We0077: Females exhibit greater mitochondrial endothelial dysfunction, impairing vascular healing in diabetes-associated peripheral artery disease.', Arteriosclerosis, Thrombosis, and Vascular Biology, 45,
    Journal articles | 2025
    Cartland S; Kelland E; Le N; Stanley C; Menezes R; Murphy M; Ku J; Boccanfuso L; Sandeman L; Beattie L; Turner L; Tumanov S; Nedoboy P; Dona M; Powell J; Thomas S; Bursill C; Pinto A; Aitken S; Robinson D; Kavurma M, 2025, 'Females exhibit greater mitochondrial endothelial dysfunction, impairing vascular healing in diabetes-associated peripheral artery disease', Atherosclerosis, 407, pp. 120337 - 120337,
    Journal articles | 2025
    Chin VT; Muskovic W; McCloy RA; Neavin DR; Alquicira-Hernandez J; Arora H; Senabouth A; Sudhakar KK; Keith P; Spenceley E; Kaczorowski D; Floros P; Leavers B; Crawford JA; Gallagher R; Powell JE, 2025, 'Protein translation dysregulation and immune cell evasion mediated by IFN and immunoproteasome downregulation define metastatic clones in HPV-related cancer of the oropharynx', BMC Medicine, 23,
    Journal articles | 2025
    Dsouza R; Skarne N; Martins P; Offenhauser C; Mulay O; Harris L; Holton E; Zaman A; Akgul S; Smith F; Alexander H; Lwin Z; Inglis P-L; Jeffree R; Powell J; Khanna R; Boyd A; Ngyuen Q; Day B, 2025, 'STEM-10. TARGETING EPH FAMILY OF RECEPTORS: ADVANCED PRECISION THERAPY FOR GBM', Neuro-Oncology, 27, pp. v79 - v80,
    Journal articles | 2025
    Korshevniuk M; Westra HJ; Oelen R; van der Wijst MGP; Franke L; Bonder MJ; Bonder MJ; Powell JE; Mel茅 M; Mahfouz A; Hemberg M; Ye J; Yazar S; Trynka G; Shin JW; Shahin T; Rajagopalan D; Park WY; Stegle O; Okada Y; Nawijn MC; Moody J; Manikanda V; Idaghdour Y; Hon CC; van der Harst P; Groot HE; Gordon MG; Dieng MM; van Blokland I; Bayaraa O; Ando Y; Vochterloo M; Ripoll-Cladellas A; Neavin D; Michielsen L; Lee JTH; Kaptijn D; Alquicira-Hern谩ndez J, 2025, 'Optimized summary-statistic-based single-cell eQTL meta-analysis', Scientific Reports, 15,
    Journal articles | 2025
    Shen S; Werner T; Lukowski SW; Andersen S; Sun Y; Shim WJ; Mizikovsky D; Kobayashi S; Outhwaite J; Chiu HS; Chen X; Chapman G; Martin EMMA; Xia D; Pham D; Su Z; Kim D; Yang P; Tan MC; Sinniah E; Zhao Q; Negi S; Redd MA; Powell JE; Dunwoodie SL; Tam PPL; Bod茅n M; Ho JWK; Nguyen Q; Palpant NJ, 2025, 'Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure', Nature Communications, 16,
    Journal articles | 2025
    Skarne N; D鈥橲ouza R; Martins P; Mulay O; Harris L; Holton E; Zaman A; Akg眉l S; Palethorpe H; Colditz M; Alexander H; Jeffree R; Powell J; Thurecht K; Khanna R; Nguyen Q; Boyd A; Gomez G; Day B, 2025, 'EXTH-76. Validating the Eph family of receptors as therapeutic targets using patient-derived Glioblastoma organoids', Neuro-Oncology, 27, pp. v356 - v356,
    Journal articles | 2025
    Zhou Y; Adeluwa T; Zhu L; Salazar-Maga帽a S; Sumner S; Kim H; Gona S; Nyasimi F; Kulkarni R; Powell JE; Madduri R; Liu B; Chen M; Im HK, 2025, 'scPrediXcan integrates deep learning methods and single-cell data into a cell-type-specific transcriptome-wide association study framework', Cell Genomics, 5,
    Journal articles | 2024
    Cartland SP; Patil MS; Kelland E; Le N; Boccanfuso L; Stanley CP; Cholan PM; Dona MI; Patrick R; McGrath J; Su QP; Alwis I; Ganss R; Powell JE; Harvey RP; Pinto AR; Griffith TS; Loa J; Aitken SJ; Robinson DA; Patel S; Kavurma MM, 2024, 'The generation of stable microvessels in ischemia is mediated by endothelial cell derived TRAIL', Science Advances, 10,
    Journal articles | 2024
    Chauquet S; Willis EF; Grice L; Harley SBR; Powell JE; Wray NR; Nguyen Q; Ruitenberg MJ; Shah S; Vukovic J, 2024, 'Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brain', Aging Cell, 23,
    Journal articles | 2024
    Chauquet S; Willis EF; Grice L; Harley SBR; Powell JE; Wray NR; Nguyen Q; Ruitenberg MJ; Shah S; Vukovic J, 2024, 'Featured Cover', Aging Cell, 23,
    Journal articles | 2024
    Chin V; McCloy RA; Sennabouth A; Neavin D; Arora H; Boyer M; Simes J; Joshua A; Brown B; Powell J, 2024, 'P1.03D.09 Single Cell RNA Sequencing and Functional Monocyte Stimulation Reveals Phenotypic Predispositions to Developing Lung Cancer in Never Smokers', Journal of Thoracic Oncology, 19, pp. S155 - S156,
    Journal articles | 2024
    Dsouza R; Skarne N; Mulay O; Harris L; Holton E; Zaman A; Akgul S; Offenhauser C; Alexander H; Lwin Z; Jeffree R; Inglis P-L; Powell J; Nguyen Q; Boyd A; Day B, 2024, 'TARGETING EPHA3 AND EPHRIN A5: ADVANCED PRECISION THERAPY FOR GBM', NEURO-ONCOLOGY, 26,
    Journal articles | 2024
    Farbehi N; Neavin DR; Cuomo ASE; Studer L; MacArthur DG; Powell JE, 2024, 'Integrating population genetics, stem cell biology and cellular genomics to study complex human diseases', Nature Genetics, 56, pp. 758 - 766,
    Journal articles | 2024
    Goldinger A; Shakhbazov K; Henders AK; McRae AF; Montgomery GW; Powell JE, 2024, 'Erratum: Correction: Seasonal Effects on Gene Expression (PloS one (2015) 10 5 DOI: 10.1371/journal.pone.0126995)', Plos One, 19, pp. e0316470,
    Journal articles | 2024
    Greatbatch CJ; Lu Q; Hung S; Barnett AJ; Wing K; Liang H; Han X; Zhou T; Siggs OM; Mackey DA; Cook AL; Senabouth A; Liu GS; Craig JE; MacGregor S; Powell JE; Hewitt AW, 2024, 'High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma', Human Molecular Genetics, 33, pp. 739 - 751,
    Journal articles | 2024
    Greatbatch CJ; Lu Q; Hung S; Tran SN; Wing K; Liang H; Han X; Zhou T; Siggs OM; Mackey DA; Liu GS; Cook AL; Powell JE; Craig JE; MacGregor S; Hewitt AW, 2024, 'Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology', Ophthalmology Science, 4,
    Journal articles | 2024
    Holton E; Muskovic W; Powell JE, 2024, 'Deciphering cancer cell state plasticity with single-cell genomics and artificial intelligence', Genome Medicine, 16,
    Journal articles | 2024
    Lim JWY; Chin VT; Keith P; McCloy R; Neavin D; Xue A; Kaczorowski D; Spenceley E; Arora H; Joshua AM; Powell J, 2024, 'Predicting immunotherapy toxicity through single-cell sequencing of peripheral immune cells: A pilot study.', Journal of Clinical Oncology, 42, pp. e14538 - e14538,
    Journal articles | 2024
    Neavin D; Senabouth A; Arora H; Lee JTH; Ripoll-Cladellas A; Franke L; Prabhakar S; Ye CJ; McCarthy DJ; Mel茅 M; Hemberg M; Powell JE, 2024, 'Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods', Genome Biology, 25,
    Journal articles | 2024
    Rumker L; Sakaue S; Reshef Y; Kang JB; Yazar S; Alquicira-Hernandez J; Valencia C; Lagattuta KA; Mah-Som A; Nathan A; Powell JE; Loh PR; Raychaudhuri S, 2024, 'Identifying genetic variants that influence the abundance of cell states in single-cell data', Nature Genetics, 56, pp. 2068 - 2077,
    Journal articles | 2024
    Wang Q; Wang M; Choi I; Sarrafha L; Liang M; Ho L; Farrell K; Beaumont KG; Sebra R; De Sanctis C; Crary JF; Ahfeldt T; Blanchard J; Neavin D; Powell J; Davis DA; Sun X; Zhang B; Yue Z, 2024, 'Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson鈥檚 disease', Science Advances, 10,
    Journal articles | 2024
    Zaman A; Muskovic W; Holton E; Pandya M; Zakanovic R; Chin V; Lam E; Yeung J; Sughrue M; Teo C; Powell J, 2024, 'A BRAIN CANCER CELL ATLAS REVEALS SHARED ASTROCYTE-LIKE STEM CELL STATES DRIVE INTRATUMOURAL HETEROGENEITY AND SHAPE IMMUNE DYNAMICS IN ADULT-TYPE DIFFUSE GLIOMAS', NEURO-ONCOLOGY, 26, pp. V3 - V3,
    Journal articles | 2024
    Zaman A; Muskovic W; Holton E; Pandya M; Zekanovic R; Chin V; Lam E; Moutinho C; Yeung J; Teo C; Sughrue M; Powell J, 2024, 'STEM-01. SHARED ASTROCYTE-LIKE GLIOMA STEM CELLS DRIVE HETEROGENEITY AND IMMUNE DYNAMICS IN ADULT-TYPE DIFFUSE GLIOMAS', Neuro-Oncology, 26, pp. viii57 - viii57,
    Journal articles | 2024
    Zhou W; Cuomo A; Xue A; Kanai M; Chau G; Krishna C; Xavier R; MacArthur D; Powell J; Daly M; Neale B, 2024, 'W28. EFFICIENT AND ACCURATE MIXED MODEL ASSOCI-ATION TOOL FOR SINGLE-CELL EQTL ANALYSIS', EUROPEAN NEUROPSYCHOPHARMACOLOGY, 87, pp. 115 - 116,
    Journal articles | 2024
    Zhou Z; Du J; Wang J; Liu L; Gordon MG; Ye CJ; Powell JE; Li MJ; Rao S, 2024, 'SingleQ: a comprehensive database of single-cell expression quantitative trait loci (sc-eQTLs) cross human tissues', Database, 2024,
    Journal articles | 2023
    Ballinger ML; Pattnaik S; Mundra PA; Zaheed M; Rath E; Priestley P; Baber J; Ray-Coquard I; Isambert N; Causeret S; van der Graaf WTA; Puri A; Duffaud F; Le Cesne A; Seddon B; Chandrasekar C; Schiffman JD; Brohl AS; James PA; Kurtz JE; Penel N; Myklebost O; Meza-Zepeda LA; Pickett H; Kansara M; Waddell N; Kondrashova O; Pearson JV; Barbour AP; Li S; Nguyen TL; Fatkin D; Graham RM; Giannoulatou E; Green MJ; Kaplan W; Ravishankar S; Copty J; Powell JE; Cuppen E; van Eijk K; Veldink J; Ahn JH; Kim JE; Lor Randall R; Tucker K; Judson I; Sarin R; Ludwig T; Genin E; Deleuze JF; Haber M; Marshall G; Cairns MJ; Blay JY; Thomas DM, 2023, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', Science, 379, pp. 253 - 260,
    Journal articles | 2023
    Brown M; Greenwood E; Gibson G, 2023, 'Effect of all-but-one conditional analysis for eQTL isolation in peripheral blood', Genetics, 223,
    Journal articles | 2023
    Cartland S; Patil M; Boccanfuso L; Kelland E; Patrick R; Cholan PM; Su Q; Ganss R; Powell J; Harvey R; Griffith T; Patel S; Kavurma M, 2023, 'TRAIL-TRAIL-R ligation regulates EC-pericyte crosstalk to generate stable microvessel networks in ischemia', Atherosclerosis, 379, pp. S22 - S23,
    Journal articles | 2023
    Cartland SP; Patil M; Boccanfuso L; Kelland E; Patrick R; Manuneedhi Cholan P; Su P; Alwis I; Ganss R; Harvey RP; Griffith TS; Powell J; Patel S; Kavurma MM, 2023, 'Abstract 597: TRAIL-TRAIL-R Ligation Regulates EC-pericyte Crosstalk To Generate Stable Microvessel Networks In Ischemia', Arteriosclerosis, Thrombosis, and Vascular Biology, 43,
    Journal articles | 2023
    Cuomo ASE; Nathan A; Raychaudhuri S; MacArthur DG; Powell JE, 2023, 'Single-cell genomics meets human genetics', Nature Reviews Genetics, 24, pp. 535 - 549,
    Journal articles | 2023
    Dai Q; Zhou G; Zhao H; V玫sa U; Franke L; Battle A; Teumer A; Lehtim盲ki T; Raitakari OT; Esko T; Agbessi M; Ahsan H; Alves I; Andiappan AK; Arindrarto W; Awadalla P; Beutner F; Jan Bonder M; Boomsma DI; Christiansen MW; Claringbould A; Deelen P; Fav茅 MJ; Frayling T; Gharib SA; Gibson G; Heijmans BT; Hemani G; Jansen R; K盲h枚nen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg J; Kukushkina V; Kutalik Z; Lee B; Loeffler M; Marigorta UM; Mei H; Milani L; Montgomery GW; M眉ller-Nurasyid M; Nauck M; Nivard MG; Penninx B; Perola M; Pervjakova N; Pierce BL; Powell J; Prokisch H; Psaty BM; Ripatti S; Rotzschke O; R眉eger S; Saha A; Scholz M; Schramm K; Sepp盲l盲 I; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; 鈥榯 Hoen PAC; Thiery J; Tong L; T枚njes A; van Dongen J; van Iterson M; van Meurs J; Veldink JH; Verlouw J; Visscher PM; V枚lker U; Westra HJ; Wijmenga C; Yaghootka H; Yang J; Zeng B; Zhang F; Epstein MP; Yang J, 2023, 'OTTERS: a powerful TWAS framework leveraging summary-level reference data', Nature Communications, 14,
    Journal articles | 2023
    Grimm L; Mason E; Yu H; Dudczig S; Panara V; Chen T; Bower NI; Paterson S; Rondon Galeano M; Kobayashi S; Senabouth A; Lagendijk AK; Powell J; Smith KA; Okuda KS; Koltowska K; Hogan BM, 2023, 'Single-cell analysis of lymphatic endothelial cell fate specification and differentiation during zebrafish development', EMBO Journal, 42,
    Journal articles | 2023
    Kang JB; Shen AZ; Gurajala S; Nathan A; Rumker L; Aguiar VRC; Valencia C; Lagattuta KA; Zhang F; Jonsson AH; Yazar S; Alquicira-Hernandez J; Khalili H; Ananthakrishnan AN; Jagadeesh K; Dey K; Albrecht J; Apruzzese W; Banda N; Barnas JL; Bathon JM; Ben-Artzi A; Boyce BF; Boyle DL; Bridges SL; Bykerk VP; Campbell D; Carr HL; Ceponis A; Chicoine A; Cordle A; Curtis M; Deane KD; DiCarlo E; Dunn P; Filer A; Firestein GS; Forbess L; Geraldino-Pardilla L; Goodman SM; Gravallese EM; Gregersen PK; Guthridge JM; Holers VM; Horowitz D; Hughes LB; Ishigaki K; Ivashkiv LB; James JA; Keras G; Korsunsky I; Lakhanpal A; Lederer JA; Lewis M; Li ZJ; Li Y; Liao KP; Mandelin AM; Mantel I; Marks KE; Maybury M; McDavid A; McGeachy MJ; Mears J; Meednu N; Millard N; Moreland LW; Nayar S; Nerviani A; Orange DE; Perlman H; Pitzalis C; Rangel-Moreno J; Raza K; Reshef Y; Ritchlin C; Rivellese F; Robinson WH; Sahbudin I; Singaraju A; Seifert JA; Slowikowski K; Smith MH; Tabechian D; Scheel-Toellner D; Utz PJ; Watts GFM; Wei K; Weinand K; Weisenfeld D; Weisman MH; Wyse A; Xiao Q; Zhu Z; Daly MJ; Xavier RJ; Donlin LT; Anolik JH; Powell JE; Rao DA, 2023, 'Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution', Nature Genetics, 55, pp. 2255 - 2268,
    Journal articles | 2023
    Khoo WH; Jackson K; Phetsouphanh C; Zaunders JJ; Alquicira-Hernandez J; Yazar S; Ruiz-Diaz S; Singh M; Dhenni R; Kyaw W; Tea F; Merheb V; Lee FXZ; Burrell R; Howard-Jones A; Koirala A; Zhou L; Yuksel A; Catchpoole DR; Lai CL; Vitagliano TL; Rouet R; Christ D; Tang B; West NP; George S; Gerrard J; Croucher PI; Kelleher AD; Goodnow CG; Sprent JD; Powell JE; Brilot F; Nanan R; Hsu PS; Deenick EK; Britton PN; Phan TG, 2023, 'Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19', Clinical Immunology, 246,
    Journal articles | 2023
    Lim J; Chin V; Fairfax K; Moutinho C; Suan D; Ji H; Powell JE, 2023, 'Transitioning single-cell genomics into the clinic', Nature Reviews Genetics, 24, pp. 573 - 584,
    Journal articles | 2023
    Neavin DR; Steinmann AM; Farbehi N; Chiu HS; Daniszewski MS; Arora H; Bermudez Y; Moutinho C; Chan CL; Bax M; Tyebally M; Gnanasambandapillai V; Lam CE; Nguyen U; Hern谩ndez D; Lidgerwood GE; Graham RM; Hewitt AW; P茅bay A; Palpant NJ; Powell JE, 2023, 'A village in a dish model system for population-scale hiPSC studies', Nature Communications, 14,
    Journal articles | 2023
    Patil M; Boccanfuso L; Kelland E; Patrick R; Cholan P; McGrath J; Su P P; Alwis I; Ganss R; Harvey R; Powell J; Griffith T; Robinson D; Patel S; Cartland S; Kavurma M, 2023, 'Improving Blood Vessel Function in Peripheral Artery Disease: TRAIL Stimulates Endothelial Cell鈥揚ericyte Interactions to Generate Stable Microvessels in Ischaemia', Heart, Lung and Circulation, 32, pp. S111 - S111,
    Journal articles | 2023
    Sarrafha L; Neavin DR; Parfitt GM; Kruglikov IA; Whitney K; Reyes R; Coccia E; Kareva T; Goldman C; Tipon R; Croft G; Crary JF; Powell JE; Blanchard J; Ahfeldt T, 2023, 'Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity', Iscience, 26,
    Journal articles | 2023
    Sikkema L; Ram铆rez-Su谩stegui C; Strobl DC; Gillett TE; Zappia L; Madissoon E; Markov NS; Zaragosi LE; Ji Y; Ansari M; Arguel MJ; Apperloo L; Banchero M; B茅cavin C; Berg M; Chichelnitskiy E; Chung MI; Collin A; Gay ACA; Gote-Schniering J; Hooshiar Kashani B; Inecik K; Jain M; Kapellos TS; Kole TM; Leroy S; Mayr CH; Oliver AJ; von Papen M; Peter L; Taylor CJ; Walzthoeni T; Xu C; Bui LT; De Donno C; Dony L; Faiz A; Guo M; Gutierrez AJ; Heumos L; Huang N; Ibarra IL; Jackson ND; Kadur Lakshminarasimha Murthy P; Lotfollahi M; Tabib T; Talavera-L贸pez C; Travaglini KJ; Wilbrey-Clark A; Worlock KB; Yoshida M; Chen Y; Hagood JS; Agami A; Horvath P; Lundeberg J; Marquette CH; Pryhuber G; Samakovlis C; Sun X; Ware LB; Zhang K; van den Berge M; Boss茅 Y; Desai TJ; Eickelberg O; Kaminski N; Krasnow MA; Lafyatis R; Nikolic MZ; Powell JE; Rajagopal J; Rojas M; Rozenblatt-Rosen O; Seibold MA; Sheppard D; Shepherd DP; Sin DD; Timens W; Tsankov AM; Whitsett J; Xu Y; Banovich NE; Barbry P; Duong TE; Falk CS; Meyer KB; Kropski JA; Pe鈥檈r D; Schiller HB; Tata PR; Schultze JL; Teichmann SA; Misharin AV; Nawijn MC; Luecken MD; Theis FJ, 2023, 'An integrated cell atlas of the lung in health and disease', Nature Medicine, 29, pp. 1563 - 1577,
    Journal articles | 2023
    Tyebally R; Xue A; Powell JE, 2023, 'The potential clinical impact of cell type-specific genetic regulation: Crohn's disease', CLINICAL AND TRANSLATIONAL MEDICINE, 13,
    Journal articles | 2023
    Xue A; Yazar S; Neavin D; Powell JE, 2023, 'Pitfalls and opportunities for applying latent variables in single-cell eQTL analyses', Genome Biology, 24,
    Journal articles | 2022
    Chin V; Arora H; Senabouth A; Hernandez JA; McCloy R; Simes J; Boyer M; Hogg P; Young J; Joshua A; Brown B; Watkins N; Powell J, 2022, 'EP16.03-041 Single Cell RNA Sequencing Reveals Phenotypic Predispositions to Developing Lung Cancer in Never-Smokers', Journal of Thoracic Oncology, 17, pp. S608 - S608,
    Journal articles | 2022
    Daniszewski M; Senabouth A; Liang HH; Han X; Lidgerwood GE; Hern谩ndez D; Sivakumaran P; Clarke JE; Lim SY; Lees JG; Rooney L; Gulluyan L; Souzeau E; Graham SL; Chan CL; Nguyen U; Farbehi N; Gnanasambandapillai V; McCloy RA; Clarke L; Kearns LS; Mackey DA; Craig JE; MacGregor S; Powell JE; P茅bay A; Hewitt AW, 2022, 'Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma', Cell Genomics, 2,
    Journal articles | 2022
    Patel B; Kleeman SO; Neavin D; Powell J; Baskozos G; Ng M; Ahmed WUR; Bennett DL; Schmid AB; Furniss D; Wiberg A, 2022, 'Shared genetic susceptibility between trigger finger and carpal tunnel syndrome: a genome-wide association study', Lancet Rheumatology, 4, pp. e556 - e565,
    Journal articles | 2022
    Phipson B; Sim CB; Porrello ER; Hewitt AW; Powell J; Oshlack A, 2022, 'propeller: testing for differences in cell type proportions in single cell data', Bioinformatics, 38, pp. 4720 - 4726,
    Journal articles | 2022
    Senabouth A; Daniszewski M; Lidgerwood GE; Liang HH; Hern谩ndez D; Mirzaei M; Keenan SN; Zhang R; Han X; Neavin D; Rooney L; Lopez Sanchez MIG; Gulluyan L; Paulo JA; Clarke L; Kearns LS; Gnanasambandapillai V; Chan CL; Nguyen U; Steinmann AM; McCloy RA; Farbehi N; Gupta VK; Mackey DA; Bylsma G; Verma N; MacGregor S; Watt MJ; Guymer RH; Powell JE; Hewitt AW; P茅bay A, 2022, 'Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration', Nature Communications, 13,
    Journal articles | 2022
    Talenti A; Powell J; Hemmink JD; Cook EAJ; Wragg D; Jayaraman S; Paxton E; Ezeasor C; Obishakin ET; Agusi ER; Tijjani A; Amanyire W; Muhanguzi D; Marshall K; Fisch A; Ferreira BR; Qasim A; Chaudhry U; Wiener P; Toye P; Morrison LJ; Connelley T; Prendergast JGD, 2022, 'A cattle graph genome incorporating global breed diversity.', Nat Commun, 13, pp. 910,
    Journal articles | 2022
    Wilson SB; Howden SE; Vanslambrouck JM; Dorison A; Alquicira-Hernandez J; Powell JE; Little MH, 2022, 'DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets', Genome Medicine, 14,
    Journal articles | 2022
    Yazar S; Alquicira-Hernandez J; Wing K; Senabouth A; Gordon MG; Andersen S; Lu Q; Rowson A; Taylor TRP; Clarke L; Maccora K; Chen C; Cook AL; Ye CJ; Fairfax KA; Hewitt AW; Powell JE, 2022, 'Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease', Science, 376,
    Journal articles | 2022
    Yazar S; Powell JE, 2022, 'Single-cell expression Quantitative Trait Loci: T-cell immunology teams up with statistical genetics', Immunology and Cell Biology, 100, pp. 588 - 590,
    Journal articles | 2022
    Zammit NW; McDowell J; Warren J; Muskovic W; Gamble J; Shi YC; Kaczorowski D; Chan CL; Powell J; Ormandy C; Brown D; Oakes SR; Grey ST, 2022, 'TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation', Frontiers in Immunology, 13,
    Journal articles | 2021
    Alquicira-Hernandez J; Powell JE; Phan TG, 2021, 'No evidence that plasmablasts transdifferentiate into developing neutrophils in severe COVID-19 disease', Clinical and Translational Immunology, 10,
    Journal articles | 2021
    Alquicira-Hernandez J; Powell JE, 2021, 'Nebulosa recovers single-cell gene expression signals by kernel density estimation', Bioinformatics, 37, pp. 2485 - 2487,
    Journal articles | 2021
    Bui LT; Winters NI; Chung MI; Joseph C; Gutierrez AJ; Habermann AC; Adams TS; Schupp JC; Poli S; Peter LM; Taylor CJ; Blackburn JB; Richmond BW; Nicholson AG; Rassl D; Wallace WA; Rosas IO; Jenkins RG; Kaminski N; Kropski JA; Banovich NE; Misharin AV; Tsankov AM; Spira A; Barbry P; Brazma A; Samakovlis C; Shepherd DP; Rawlins EL; Theis FJ; Griffonnet J; Lee H; Schiller HB; Hofman P; Powell JE; Schultze JL; Whitsett J; Choi J; Lundeberg J; Ordovas-Montanes J; Rajagopal J; Meyer KB; Krasnow MA; Saeb鈥怭arsy K; Zhang K; Lafyatis R; Leroy S; Haniffa M; Nawijn MC; Nikoli膰 MZ; van den Berge M; Kuhnemund M; Marquette CH; Von Papen M; Eickelberg O; Rosenblatt-Rosen O; Reyfman PA; Pe鈥檈r D; Horvath P; Tata PR; Regev A; Rojas M; Seibold MA; Shalek AK; Spence JR; Teichmann SA; Quake S; Duong TE; Biancalani T; Desai T; Sun X; Zaragosi LE, 2021, 'Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity', Nature Communications, 12,
    Journal articles | 2021
    Chin V; Stone E; Havryk A; Plit M; Mccloy R; Murphy A; Field A; Watkins N; Powell J, 2021, 'P60.01 Single-Cell Transcriptomics to Assess Response to Immunotherapy in Advanced Lung Cancer ex-vivo: Developing a Functional Predictive Assay', Journal of Thoracic Oncology, 16, pp. S540 - S541,
    Journal articles | 2021
    Cohen J; Blumenthal A; Cuellar-Partida G; Evans DM; Finfer S; Li Q; Ljungberg J; Myburgh J; Peach E; Powell J; Rajbhandari D; Rhodes A; Senabouth A; Venkatesh B, 2021, 'The relationship between adrenocortical candidate gene expression and clinical response to hydrocortisone in patients with septic shock', Intensive Care Medicine, 47, pp. 974 - 983,
    Journal articles | 2021
    Currant H; Hysi P; Fitzgerald TW; Gharahkhani P; Bonnemaijer PWM; Senabouth A; Hewitt AW; Atan D; Aung T; Charng J; Choquet H; Craig J; Khaw PT; Klaver CCW; Kubo M; Ong JS; Pasquale LR; Reisman CA; Daniszewski M; Powell JE; P茅bay A; Simcoe MJ; Thiadens AAHJ; van Duijn CM; Yazar S; Jorgenson E; MacGregor S; Hammond CJ; Mackey DA; Wiggs JL; Foster PJ; Patel PJ; Birney E; Khawaja AP, 2021, 'Erratum: Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images (PLoS Genet (2021) 17:5 (e1009497) DOI: 10.1371/journal.pgen.1009497)', Plos Genetics, 17,
    Journal articles | 2021
    Currant H; Hysi P; Fitzgerald TW; Gharahkhani P; Bonnemaijer PWM; Senabouth A; Hewitt AW; Atan D; Aung T; Charng J; Choquet H; Craig J; Khaw PT; Klaver CCW; Kubo M; Ong JS; Pasquale LR; Reisman CA; Daniszewski M; Powell JE; P茅bay A; Simcoe MJ; Thiadens AAHJ; van Duijn CM; Yazar S; Jorgenson E; MacGregor S; Hammond CJ; Mackey DA; Wiggs JL; Foster PJ; Patel PJ; Birney E; Khawaja AP, 2021, 'Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images', Plos Genetics, 17,
    Journal articles | 2021
    Du Q; Smith GC; Luu PL; Ferguson JM; Armstrong NJ; Caldon CE; Campbell EM; Nair SS; Zotenko E; Gould CM; Buckley M; Chia KM; Portman N; Lim E; Kaczorowski D; Chan CL; Barton K; Deveson IW; Smith MA; Powell JE; Skvortsova K; Stirzaker C; Achinger-Kawecka J; Clark SJ, 2021, 'DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity', Cell Reports, 36,
    Journal articles | 2021
    Hemani G; Powell JE; Wang H; Shakhbazov K; Westra HJ; Esko T; Henders AK; McRae AF; Martin NG; Metspalu A; Franke L; Montgomery GW; Goddard ME; Gibson G; Yang J; Visscher PM, 2021, 'Phantom epistasis between unlinked loci', Nature, 596, pp. E1 - E3,
    Journal articles | 2021
    Hemani G; Shakhbazov K; Westra HJ; Esko T; Henders AK; McRae AF; Yang J; Gibson G; Martin NG; Metspalu A; Franke L; Montgomery GW; Visscher PM; Powell JE, 2021, 'Retraction Note: Detection and replication of epistasis influencing transcription in humans (Nature, (2014), 508, 7495, (249-253), 10.1038/nature13005)', Nature, 596, pp. 306,
    Journal articles | 2021
    Lidgerwood GE; Senabouth A; Smith-Anttila CJA; Gnanasambandapillai V; Kaczorowski DC; Amann-Zalcenstein D; Fletcher EL; Naik SH; Hewitt AW; Powell JE; P茅bay A, 2021, 'Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time', Genomics Proteomics and Bioinformatics, 19, pp. 223 - 242,
    Journal articles | 2021
    Mills MC; Tropf FC; Brazel DM; van Zuydam N; Vaez A; Agbessi M; Ahsan H; Alves I; Andiappan AK; Arindrarto W; Awadalla P; Battle A; Beutner F; Jan Bonder M; Boomsma DI; Christiansen MW; Claringbould A; Deelen P; Esko T; Fav茅 MJ; Franke L; Frayling T; Gharib SA; Gibson G; Heijmans BT; Hemani G; Jansen R; K盲h枚nen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg J; Kukushkina V; Kutalik Z; Lee B; Lehtim盲ki T; Loeffler M; Marigorta UM; Mei H; Milani L; Montgomery GW; M眉ller-Nurasyid M; Nauck M; Nivard MG; Penninx BWJH; Perola M; Pervjakova N; Pierce BL; Powell J; Prokisch H; Psaty BM; Raitakari OT; Ripatti S; Rotzschke O; R眉eger S; Saha A; Scholz M; Schramm K; Sepp盲l盲 I; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; 鈥榯 Hoen PAC; Teumer A; Thiery J; Tong L; T枚njes A; van Dongen J; van Iterson M; van Meurs J; Veldink JH; Verlouw J; Visscher PM; V枚lker U; V玫sa U; Westra HJ; Wijmenga C; Yaghootkar H; Yang J; Zeng B; Zhang F; Akimova ET; Bergmann S; Boardman JD; Brumat M; Buring JE; Cesarini D; Chasman DI; Chavarro JE; Cocca M; Concas MP; Davey-Smith G; Davies G; Deary IJ; Esko T, 2021, 'Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour', Nature Human Behaviour, 5, pp. 1717 - 1730,
    Journal articles | 2021
    Muskovic W; Powell JE, 2021, 'DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data', Genome Biology, 22,
    Journal articles | 2021
    Muus C; Luecken MD; Eraslan G; Sikkema L; Waghray A; Heimberg G; Kobayashi Y; Vaishnav ED; Subramanian A; Smillie C; Jagadeesh KA; Duong ET; Fiskin E; Triglia ET; Ansari M; Cai P; Lin B; Buchanan J; Chen S; Shu J; Haber AL; Chung H; Montoro DT; Adams T; Aliee H; Allon SJ; Andrusivova Z; Angelidis I; Ashenberg O; Bassler K; B茅cavin C; Benhar I; Bergenstr氓hle J; Bergenstr氓hle L; Bolt L; Braun E; Bui LT; Callori S; Chaffin M; Chichelnitskiy E; Chiou J; Conlon TM; Cuoco MS; Cuomo ASE; Deprez M; Duclos G; Fine D; Fischer DS; Ghazanfar S; Gillich A; Giotti B; Gould J; Guo M; Gutierrez AJ; Habermann AC; Harvey T; He P; Hou X; Hu L; Hu Y; Jaiswal A; Ji L; Jiang P; Kapellos TS; Kuo CS; Larsson L; Leney-Greene MA; Lim K; Litvi艌ukov谩 M; Ludwig LS; Lukassen S; Luo W; Maatz H; Madissoon E; Mamanova L; Manakongtreecheep K; Leroy S; Mayr CH; Mbano IM; McAdams AM; Nabhan AN; Nyquist SK; Penland L; Poirion OB; Poli S; Qi CC; Queen R; Reichart D; Rosas I; Schupp JC; Shea CV; Shi X; Sinha R; Sit RV; Slowikowski K; Slyper M; Smith NP; Sountoulidis A; Strunz M; Sullivan TB; Powell J, 2021, 'Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics', Nature Medicine, 27, pp. 546 - 559,
    Journal articles | 2021
    Neavin D; Nguyen Q; Daniszewski MS; Liang HH; Chiu HS; Wee YK; Senabouth A; Lukowski SW; Crombie DE; Lidgerwood GE; Hern谩ndez D; Vickers JC; Cook AL; Palpant NJ; P茅bay A; Hewitt AW; Powell JE, 2021, 'Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells', Genome Biology, 22,
    Journal articles | 2021
    Nieto P; Elosua-Bayes M; Trincado JL; Marchese D; Massoni-Badosa R; Salvany M; Henriques A; Nieto J; Aguilar-Fern谩ndez S; Mereu E; Moutinho C; Ruiz S; Lorden P; Chin VT; Kaczorowski D; Chan CL; Gallagher R; Chou A; Planas-Rigol E; Rubio-Perez C; Gut I; Piulats JM; Seoane J; Powell JE; Batlle E; Heyn H, 2021, 'A single-cell tumor immune atlas for precision oncology', Genome Research, 31, pp. 1913 - 1926,
    Journal articles | 2021
    Shen S; Sun Y; Matsumoto M; Shim WJ; Sinniah E; Wilson SB; Werner T; Wu Z; Bradford ST; Hudson J; Little MH; Powell J; Nguyen Q; Palpant NJ, 2021, 'Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation', Trends in Molecular Medicine, 27, pp. 1135 - 1158,
    Journal articles | 2021
    Sinclair KA; Yerkovich ST; Hopkins PMA; Fieuw AM; Ford P; Powell JE; O'Sullivan B; Chambers DC, 2021, 'The autotaxin-lysophosphatidic acid pathway mediates mesenchymal cell recruitment and fibrotic contraction in lung transplant fibrosis', Journal of Heart and Lung Transplantation, 40, pp. 12 - 23,
    Journal articles | 2021
    Thompson M; Matsumoto M; Ma T; Senabouth A; Palpant NJ; Powell JE; Nguyen Q, 2021, 'scGPS: Determining Cell States and Global Fate Potential of Subpopulations', Frontiers in Genetics, 12,
    Journal articles | 2021
    Tuong ZK; Lukowski SW; Nguyen QH; Chandra J; Zhou C; Gillinder K; Bashaw AA; Ferdinand JR; Stewart BJ; Teoh SM; Hanson SJ; Devitt K; Clatworthy MR; Powell JE; Frazer IH, 2021, 'A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia', Iscience, 24,
    Journal articles | 2021
    V玫sa U; Claringbould A; Westra HJ; Bonder MJ; Deelen P; Zeng B; Kirsten H; Saha A; Kreuzhuber R; Yazar S; Brugge H; Oelen R; de Vries DH; van der Wijst MGP; Kasela S; Pervjakova N; Alves I; Fav茅 MJ; Agbessi M; Christiansen MW; Jansen R; Sepp盲l盲 I; Tong L; Teumer A; Schramm K; Hemani G; Verlouw J; Yaghootkar H; S枚nmez Flitman R; Brown A; Kukushkina V; Kalnapenkis A; R眉eger S; Porcu E; Kronberg J; Kettunen J; Lee B; Zhang F; Qi T; Hernandez JA; Arindrarto W; Beutner F; 鈥檛 Hoen PAC; van Meurs J; van Dongen J; van Iterson M; Swertz MA; Jan Bonder M; Dmitrieva J; Elansary M; Fairfax BP; Georges M; Heijmans BT; Hewitt AW; K盲h枚nen M; Kim Y; Knight JC; Kovacs P; Krohn K; Li S; Loeffler M; Marigorta UM; Mei H; Momozawa Y; M眉ller-Nurasyid M; Nauck M; Nivard MG; Penninx BWJH; Pritchard JK; Raitakari OT; Rotzschke O; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; Thiery J; T枚njes A; Veldink JH; V枚lker U; Warmerdam R; Wijmenga C; Andiappan A; Montgomery GW; Ripatti S; Perola M; Kutalik Z; Dermitzakis E; Bergmann S; Frayling T; Prokisch H; Ahsan H; Pierce BL; Lehtim盲ki T; Boomsma DI; Psaty BM; Gharib SA; Awadalla P, 2021, 'Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression', Nature Genetics, 53, pp. 1300 - 1310,
    Journal articles | 2021
    Wu SZ; Al-Eryani G; Roden DL; Junankar S; Harvey K; Andersson A; Thennavan A; Wang C; Torpy JR; Bartonicek N; Wang T; Larsson L; Kaczorowski D; Weisenfeld NI; Uytingco CR; Chew JG; Bent ZW; Chan CL; Gnanasambandapillai V; Dutertre CA; Gluch L; Hui MN; Beith J; Parker A; Robbins E; Segara D; Cooper C; Mak C; Chan B; Warrier S; Ginhoux F; Millar E; Powell JE; Williams SR; Liu XS; O鈥橳oole S; Lim E; Lundeberg J; Perou CM; Swarbrick A, 2021, 'A single-cell and spatially resolved atlas of human breast cancers', Nature Genetics, 53, pp. 1334 - 1347,
    Journal articles | 2021
    Wu SZ; Roden DL; Al-Eryani G; Bartonicek N; Harvey K; Cazet AS; Chan CL; Junankar S; Hui MN; Millar EA; Beretov J; Horvath L; Joshua AM; Stricker P; Wilmott JS; Quek C; Long GV; Scolyer RA; Yeung BZ; Segara D; Mak C; Warrier S; Powell JE; O鈥橳oole S; Lim E; Swarbrick A, 2021, 'Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis', Genome Medicine, 13,
    Journal articles | 2020
    Avila Cobos F; Alquicira-Hernandez J; Powell JE; Mestdagh P; De Preter K, 2020, 'Benchmarking of cell type deconvolution pipelines for transcriptomics data', Nature Communications, 11,
    Journal articles | 2020
    Byrne AJ; Powell JE; O鈥橲ullivan BJ; Ogger PP; Hoffland A; Cook J; Bonner KL; Hewitt RJ; Wolf S; Ghai P; Walker SA; Lukowski SW; Molyneaux PL; Saglani S; Chambers DC; Maher TM; Lloyd CM, 2020, 'Dynamics of human monocytes and airway macrophages during healthy aging and after transplant', Journal of Experimental Medicine, 217,
    Journal articles | 2020
    Cobos FA; Alquicira-Hernandez J; Powell JE; Mestdagh P; De Preter K, 2020, 'Author Correction: Benchmarking of cell type deconvolution pipelines for transcriptomics data (Nature Communications, (2020), 11, 1, (5650), 10.1038/s41467-020-19015-1)', Nature Communications, 11,
    Journal articles | 2020
    D'Urso S; Rajbhandari D; Peach E; De Guzman E; Li Q; Medland SE; Gordon SD; Martin NG; Ligthart S; Brown MA; Powell J; McArthur C; Rhodes A; Meyer J; Finfer S; Myburgh J; Blumenthal A; Cohen J; Venkatesh B; Cuellar-Partida G; Evans DM, 2020, 'Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis', Twin Research and Human Genetics, 23, pp. 204 - 213,
    Journal articles | 2020
    Du Q; Smith G; Luu PL; Ferguson J; Armstrong N; Caldon E; Campbell E; Nair S; Zotenko E; Gould C; Buckley M; Kaczorowski D; Barton K; Deveson I; Smith M; Powell J; Skvortsova K; Stirzaker C; Achinger-Kawecka J; Clark S, 2020, 'DNA methylation is required to maintain DNA replication timing precision and 3D genome integrity', ,
    Journal articles | 2020
    Engel JA; Lee HJ; Williams CG; Kuns R; Olver S; Lansink LIM; Soon MSF; Andersen SB; Powell JE; Svensson V; Teichmann SA; Hill GR; Varelias A; Koyama M; Haque A, 2020, 'Single-cell transcriptomics of alloreactive CD4+ T cells over time reveals divergent fates during gut graft-versus-host disease', Jci Insight, 5,
    Journal articles | 2020
    Hammerschlag AR; Byrne EM; Agbessi M; Ahsan H; Alves I; Andiappan A; Arindrarto W; Awadalla P; Battle A; Beutner F; Bonder MJ; Boomsma DI; Christiansen M; Claringbould A; Deelen P; Esko T; Fav茅 MJ; Franke L; Frayling T; Gharib SA; Gibson G; Heijmans BT; Hemani G; Jansen R; K盲h枚nen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg-Guzman J; Kukushkina V; Kutalik Z; Lee B; Lehtim盲ki T; Loeffler M; Marigorta UM; Mei H; Milani L; Montgomery GW; M眉ller-Nurasyid M; Nauck M; Nivard M; Penninx B; Perola M; Pervjakova N; Pierce BL; Powell J; Prokisch H; Psaty BM; Raitakari OT; Ripatti S; Rotzschke O; R眉eger S; Saha A; Scholz M; Schramm K; Sepp盲l盲 I; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; 鈥榯 Hoen PAC; Teumer A; Thiery J; Tong L; T枚njes A; van Dongen J; van Iterson M; van Meurs J; Veldink JH; Verlouw J; Visscher PM; V枚lker U; V玫sa U; Westra HJ; Wijmenga C; Yaghootkar H; Yang J; Zeng B; Zhang F; Isaacs A; Pool R; Hottenga JJ; van Greevenbroek MM; van der Kallen CJH; Schalkwijk CG; Zhernakova S; Tigchelaar EF; Beekman M; Deelen J; van Heemst D; van den Berg LH; van Duijn CM; Hofman BA; Uitterlinden AG; Jhamai PM; Verbiest M, 2020, 'Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies', Biological Psychiatry, 88, pp. 470 - 479,
    Journal articles | 2020
    Kott KA; Vernon ST; Hansen T; de Dreu M; Das SK; Powell J; de St Groth BF; Di Bartolo BA; McGuire HM; Figtree GA, 2020, 'Single-cell immune profiling in coronary artery disease: The role of state-of-the-art immunophenotyping with mass cytometry in the diagnosis of atherosclerosis', Journal of the American Heart Association, 9,
    Journal articles | 2020
    Ogger PP; Albers GJ; Hewitt RJ; O鈥橲ullivan BJ; Powell JE; Calamita E; Ghai P; Walker SA; McErlean P; Saunders P; Kingston S; Molyneaux PL; Halket JM; Gray R; Chambers DC; Maher TM; Lloyd CM; Byrne AJ, 2020, 'Itaconate controls the severity of pulmonary fibrosis', Science Immunology, 5,
    Journal articles | 2020
    Pinese M; Lacaze P; Rath EM; Stone A; Brion MJ; Ameur A; Nagpal S; Puttick C; Husson S; Degrave D; Cristina TN; Kahl VFS; Statham AL; Woods RL; McNeil JJ; Riaz M; Barr M; Nelson MR; Reid CM; Murray AM; Shah RC; Wolfe R; Atkins JR; Fitzsimmons C; Cairns HM; Green MJ; Carr VJ; Cowley MJ; Pickett HA; James PA; Powell JE; Kaplan W; Gibson G; Gyllensten U; Cairns MJ; McNamara M; Dinger ME; Thomas DM, 2020, 'The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly', Nature Communications, 11, pp. 435,
    Journal articles | 2020
    Senabouth A; Andersen S; Shi Q; Shi L; Jiang F; Zhang W; Wing K; Daniszewski M; Lukowski SW; Hung SSC; Nguyen Q; Fink L; Beckhouse A; P茅bay A; Hewitt AW; Powell JE, 2020, 'Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing', Nar Genomics and Bioinformatics, 2,
    Journal articles | 2020
    Sungnak W; Huang N; B茅cavin C; Berg M; Queen R; Litvinukova M; Talavera-L贸pez C; Maatz H; Reichart D; Sampaziotis F; Worlock KB; Yoshida M; Barnes JL; Banovich NE; Barbry P; Brazma A; Collin J; Desai TJ; Duong TE; Eickelberg O; Falk C; Farzan M; Glass I; Gupta RK; Haniffa M; Horvath P; Hubner N; Hung D; Kaminski N; Krasnow M; Kropski JA; Kuhnemund M; Lako M; Lee H; Leroy S; Linnarson S; Lundeberg J; Meyer KB; Miao Z; Misharin AV; Nawijn MC; Nikolic MZ; Noseda M; Ordovas-Montanes J; Oudit GY; Pe鈥檈r D; Powell J; Quake S; Rajagopal J; Tata PR; Rawlins EL; Regev A; Reyfman PA; Rozenblatt-Rosen O; Saeb-Parsy K; Samakovlis C; Schiller HB; Schultze JL; Seibold MA; Seidman CE; Seidman JG; Shalek AK; Shepherd D; Spence J; Spira A; Sun X; Teichmann SA; Theis FJ; Tsankov AM; Vallier L; van den Berge M; Whitsett J; Xavier R; Xu Y; Zaragosi LE; Zerti D; Zhang H; Zhang K; Rojas M; Figueiredo F, 2020, 'SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes', Nature Medicine, 26, pp. 681 - 687,
    Journal articles | 2020
    Tucker NR; Chaffin M; Bedi KC; Papangeli I; Akkad A-D; Arduini A; Hayat S; Eraslan G; Muus C; Bhattacharyya RP; Stegmann CM; Margulies KB; Ellinor PT; Powell J, 2020, 'Myocyte Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2 Mediated Myocarditis', Circulation, 142, pp. 708 - 710,
    Journal articles | 2020
    Wu S; Roden D; Al-Eryani G; Bartonicek N; Harvey K; Cazet A; Chan C-L; Junankar S; Hui M; Millar E; Beretov J; Horvath L; Joshua A; Stricker P; Wilmott J; Quek C; Long G; Scolyer R; Yeung B; Segara D; Mak C; Warrier S; Powell J; O'Toole S; Lim E; Swarbrick A, 2020, 'Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis', bioRxiv,
    Journal articles | 2020
    Wu S; Roden D; Wang C; Holliday H; Harvey K; Cazet A; Murphy K; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy J; Junankar S; Chan C-L; Lam E; Hui M; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O鈥橳oole S; Cox T; Timpson P; Lim E; Liu S; Swarbrick A, 2020, 'Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer', bioRxiv,
    Journal articles | 2020
    Wu SZ; Roden DL; Wang C; Holliday H; Harvey K; Cazet AS; Murphy KJ; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy JR; Junankar S; Chan CL; Lam CE; Hui MN; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O'Toole S; Cox TR; Timpson P; Lim E; Liu XS; Swarbrick A, 2020, 'Stromal cell diversity associated with immune evasion in human triple-negative breast cancer', EMBO Journal, 39, pp. embj2019104063,
    Journal articles | 2020
    Ziegler CGK; Allon SJ; Nyquist SK; Mbano IM; Miao VN; Tzouanas CN; Cao Y; Yousif AS; Bals J; Hauser BM; Feldman J; Muus C; Wadsworth MH; Kazer SW; Hughes TK; Doran B; Gatter GJ; Vukovic M; Taliaferro F; Mead BE; Guo Z; Wang JP; Gras D; Plaisant M; Ansari M; Angelidis I; Adler H; Sucre JMS; Taylor CJ; Lin B; Waghray A; Mitsialis V; Dwyer DF; Buchheit KM; Boyce JA; Barrett NA; Laidlaw TM; Carroll SL; Colonna L; Tkachev V; Peterson CW; Yu A; Zheng HB; Gideon HP; Winchell CG; Lin PL; Bingle CD; Snapper SB; Kropski JA; Theis FJ; Schiller HB; Zaragosi LE; Barbry P; Leslie A; Kiem HP; Flynn JAL; Fortune SM; Berger B; Finberg RW; Kean LS; Garber M; Schmidt AG; Lingwood D; Shalek AK; Ordovas-Montanes J; Banovich N; Brazma A; Desai T; Duong TE; Eickelberg O; Falk C; Farzan M; Glass I; Haniffa M; Horvath P; Hung D; Kaminski N; Krasnow M; Kuhnemund M; Lafyatis R; Lee H; Leroy S; Linnarson S; Lundeberg J; Meyer K; Misharin A; Nawijn M; Nikolic MZ; Pe'er D; Powell J; Quake S; Rajagopal J; Tata PR; Rawlins EL; Regev A; Reyfman PA; Rojas M; Rosen O; Saeb-Parsy K; Samakovlis C, 2020, 'SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues', Cell, 181, pp. 1016 - 1035.e19,
    Journal articles | 2020
    van der Wijst MGP; de Vries DH; Groot HE; Trynka G; Hon CC; Bonder MJ; Stegle O; Nawijn MC; Idaghdour Y; van der Harst P; Ye CJ; Powell J; Theis FJ; Mahfouz A; Heinig M; Franke L, 2020, 'The single-cell eQTLGen consortium', Elife, 9,
    Journal articles | 2019
    Alquicira-Hernandez J; Sathe A; Ji HP; Nguyen Q; Powell JE, 2019, 'ScPred: Accurate supervised method for cell-type classification from single-cell RNA-seq data', Genome Biology, 20,
    Journal articles | 2019
    Chambers DC; Carew AM; Lukowski SW; Powell JE, 2019, 'Transcriptomics and single-cell RNA-sequencing', Respirology, 24, pp. 29 - 36,
    Journal articles | 2019
    Karlsson Linn茅r R; Biroli P; Kong E; Meddens SFW; Wedow R; Fontana MA; Lebreton M; Tino SP; Abdellaoui A; Hammerschlag AR; Nivard MG; Okbay A; Rietveld CA; Timshel PN; Trzaskowski M; Vlaming RD; Z眉nd CL; Bao Y; Buzdugan L; Caplin AH; Chen CY; Eibich P; Fontanillas P; Gonzalez JR; Joshi PK; Karhunen V; Kleinman A; Levin RZ; Lill CM; Meddens GA; Muntan茅 G; Sanchez-Roige S; Rooij FJV; Taskesen E; Wu Y; Zhang F; Agee M; Alipanahi B; Bell RK; Bryc K; Elson SL; Furlotte NA; Huber KE; Litterman NK; McCreight JC; McIntyre MH; Mountain JL; Northover CAM; Pitts SJ; Sathirapongsasuti JF; Sazonova OV; Shelton JF; Shringarpure S; Tian C; Tung JY; Vacic V; Wilson CH; Agbessi M; Ahsan H; Alves I; Andiappan A; Awadalla P; Battle A; Beutner F; Jan Bonder M; Boomsma DI; Christiansen M; Claringbould A; Deelen P; Esko T; Fav茅 MJ; Franke L; Frayling T; Gharib SA; Gibson G; Heijmans B; Hemani G; Jansen R; K盲h枚nen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg-Guzman J; Kukushkina V; Kutalik Z; Lee B; Lehtim盲ki T; Loeffler M; Marigorta UM; Metspalu A; Milani L; Montgomery GW; M眉ller-Nurasyid M; Nauck M; Penninx B; Perola M, 2019, 'Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences', Nature Genetics, 51, pp. 245 - 257,
    Journal articles | 2019
    Lukowski SW; Lo CY; Sharov AA; Nguyen Q; Fang L; Hung SSC; Zhu L; Zhang T; Gr眉nert U; Nguyen T; Senabouth A; Jabbari JS; Welby E; Sowden JC; Waugh HS; Mackey A; Pollock G; Lamb TD; Wang PY; Hewitt AW; Gillies MC; Powell JE; Wong RCB, 2019, 'A single-cell transcriptome atlas of the adult human retina', EMBO Journal, 38,
    Journal articles | 2019
    Lukowski SW; Patel J; Andersen SB; Sim SL; Wong HY; Tay J; Winkler I; Powell JE; Khosrotehrani K, 2019, 'Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells', Cell Reports, 27, pp. 2748 - 2758.e3,
    Journal articles | 2019
    O'Sullivan B; Powell J; Lukowski S; Tan M; Hopkins P; Chambers D, 2019, 'Reconstruction of Transcriptional Programs of Monocyte to Macrophage Sequential Cell Fate Transition Using Single Cell RNA Sequencing in Sex Mis-Matched Lung Transplantation', The Journal of Heart and Lung Transplantation, 38, pp. S157 - S157,
    Journal articles | 2019
    Porcu E; R眉eger S; Lepik K; Agbessi M; Ahsan H; Alves I; Andiappan A; Arindrarto W; Awadalla P; Battle A; Beutner F; Bonder MJ; Boomsma DI; Christiansen M; Claringbould A; Deelen P; Esko T; Fav茅 MJ; Franke L; Frayling T; Gharib SA; Gibson G; Heijmans BT; Hemani G; Jansen R; K盲h枚nen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg-Guzman J; Kukushkina V; Lee B; Lehtim盲ki T; Loeffler M; Marigorta UM; Mei H; Milani L; Montgomery GW; M眉ller-Nurasyid M; Nauck M; Nivard M; Penninx B; Perola M; Pervjakova N; Pierce BL; Powell J; Prokisch H; Psaty BM; Raitakari OT; Ripatti S; Rotzschke O; Saha A; Scholz M; Schramm K; Sepp盲l盲 I; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; 鈥榯 Hoen PAC; Teumer A; Thiery J; Tong L; T枚njes A; van Dongen J; van Iterson M; van Meurs J; Veldink JH; Verlouw J; Visscher PM; V枚lker U; V玫sa U; Westra HJ; Wijmenga C; Yaghootkar H; Yang J; Zeng B; Zhang F; Beekman M; Bot J; Deelen J; Hofman BA; Hottenga JJ; Isaacs A; Jhamai PM; Kielbasa SM; Lakenberg N; Luijk R; Mei H; Moed M; Nooren I, 2019, 'Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits', Nature Communications, 10,
    Journal articles | 2019
    Senabouth A; Lukowski SW; Hernandez JA; Andersen SB; Mei X; Nguyen QH; Powell JE, 2019, 'Ascend: R package for analysis of single-cell RNA-seq data', Gigascience, 8,
    Journal articles | 2019
    Timmers PRHJ; Mounier N; Lall K; Fischer K; Ning Z; Feng X; Bretherick AD; Clark DW; Shen X; Esko T; Kutalik Z; Wilson JF; Joshi PK, 2019, 'Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances', Elife, 8, pp. 1 - 40,
    Journal articles | 2019
    Wang H; Zhang F; Zeng J; Wu Y; Kemper KE; Xue A; Zhang M; Powell JE; Goddard ME; Wray NR; Visscher PM; McRae AF; Yang J, 2019, 'Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank', Science Advances, 5,
    Journal articles | 2019
    Xu J; Falconer C; Nguyen Q; Crawford J; McKinnon BD; Mortlock S; Senabouth A; Andersen S; Chiu HS; Jiang L; Palpant NJ; Yang J; Mueller MD; Hewitt AW; P茅bay A; Montgomery GW; Powell JE; Coin LJM, 2019, 'Genotype-free demultiplexing of pooled single-cell RNA-seq', Genome Biology, 20,
    Journal articles | 2019
    Zeng B; Lloyd-Jones LR; Montgomery GW; Metspalu A; Esko T; Franke L; Vosa U; Claringbould A; Brigham KL; Quyyumi AA; Idaghdour Y; Yang J; Visscher PM; Powell JE; Gibson G, 2019, 'Comprehensive multiple eQTL detection and its application to GWAS interpretation', Genetics, 212, pp. 905 - 918,
    Journal articles | 2018
    Daniszewski M; Nguyen Q; Chy HS; Singh V; Crombie DE; Kulkarni T; Liang HH; Sivakumaran P; Lidgerwood GE; Hern谩ndez D; Conquest A; Rooney LA; Chevalier S; Andersen SB; Senabouth A; Vickers JC; Mackey DA; Craig JE; Laslett AL; Hewitt AW; Powell JE; P茅bay A, 2018, 'Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media', Iscience, 7, pp. 30 - 39,
    Journal articles | 2018
    Daniszewski M; Senabouth A; Nguyen QH; Crombie DE; Lukowski SW; Kulkarni T; Sluch VM; Jabbari JS; Chamling X; Zack DJ; P茅bay A; Powell JE; Hewitt AW, 2018, 'Single cell RNA sequencing of stem cell-derived retinal ganglion cells', Scientific Data, 5,
    Journal articles | 2018
    De Smit E; Lukowski SW; Anderson L; Senabouth A; Dauyey K; Song S; Wyse B; Wheeler L; Chen CY; Cao K; Wong Ten Yuen A; Shuey N; Clarke L; Lopez Sanchez I; Hung SSC; P茅bay A; Mackey DA; Brown MA; Hewitt AW; Powell JE, 2018, 'Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis', BMC Medical Genomics, 11,
    Journal articles | 2018
    Friedman CE; Nguyen Q; Lukowski SW; Helfer A; Chiu HS; Miklas J; Levy S; Suo S; Han JDJ; Osteil P; Peng G; Jing N; Baillie GJ; Senabouth A; Christ AN; Bruxner TJ; Murry CE; Wong ES; Ding J; Wang Y; Hudson J; Ruohola-Baker H; Bar-Joseph Z; Tam PPL; Powell JE; Palpant NJ, 2018, 'Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation', Cell Stem Cell, 23, pp. 586 - 598.e8,
    Journal articles | 2018
    Fung JN; Mortlock S; Girling JE; Holdsworth-Carson SJ; Teh WT; Zhu Z; Lukowski SW; McKinnon BD; McRae A; Yang J; Healey M; Powell JE; Rogers PAW; Montgomery GW, 2018, 'Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome', Scientific Reports, 8,
    Journal articles | 2018
    Gerring ZF; Powell JE; Montgomery GW; Nyholt DR, 2018, 'Genome-wide analysis of blood gene expression in migraine implicates immune-inflammatory pathways', Cephalalgia, 38, pp. 292 - 303,
    Journal articles | 2018
    Lukowski SW; Tuong ZK; Noske K; Senabouth A; Nguyen QH; Andersen SB; Soyer HP; Frazer IH; Powell JE, 2018, 'Detection of HPV E7 Transcription at Single-Cell Resolution in Epidermis', Journal of Investigative Dermatology, 138, pp. 2558 - 2567,
    Journal articles | 2018
    MacGregor S; Ong JS; An J; Han X; Zhou T; Siggs OM; Law MH; Souzeau E; Sharma S; Lynn DJ; Beesley J; Sheldrick B; Mills RA; Landers J; Ruddle JB; Graham SL; Healey PR; White AJR; Casson RJ; Best S; Grigg JR; Goldberg I; Powell JE; Whiteman DC; Radford-Smith GL; Martin NG; Montgomery GW; Burdon KP; Mackey DA; Gharahkhani P; Craig JE; Hewitt AW, 2018, 'Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma', Nature Genetics, 50, pp. 1067 - 1071,
    Journal articles | 2018
    McRae AF; Marioni RE; Shah S; Yang J; Powell JE; Harris SE; Gibson J; Henders AK; Bowdler L; Painter JN; Murphy L; Martin NG; Starr JM; Wray NR; Deary IJ; Visscher PM; Montgomery GW, 2018, 'Identification of 55,000 Replicated DNA Methylation QTL', Scientific Reports, 8,
    Journal articles | 2018
    Nguyen QH; Lukowski SW; Chiu HS; Senabouth A; Bruxner TJC; Christ AN; Palpant NJ; Powell JE, 2018, 'Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations', Genome Research, 28, pp. 1053 - 1066,
    Journal articles | 2018
    Pinese M; Lacaze P; Rath E; Stone A; Brion M-J; Ameur A; Nagpal S; Puttick C; Husson S; Degrave D; Navin Cristina T; Silva Kahl V; Statham A; Woods R; McNeil J; Riaz M; Barr M; Nelson M; Reid C; Murray A; Shah R; Wolfe R; Atkins J; Fitzsimmons C; Cairns H; Green M; Carr V; Cowley M; Pickett H; James P; Powell J; Kaplan W; Gibson G; Gyllensten U; Cairns M; McNamara M; Dinger M; Thomas D, 2018, 'The Medical Genome Reference Bank: Whole genomes and phenotype of 2,570 healthy elderly', bioRxiv, pp. 473348,
    Journal articles | 2018
    Qi T; Wu Y; Zeng J; Zhang F; Xue A; Jiang L; Zhu Z; Kemper K; Yengo L; Zheng Z; Agbessi M; Ahsan H; Alves I; Andiappan A; Awadalla P; Battle A; Beutner F; Jan Bonder M; Boomsma D; Christiansen M; Claringbould A; Deelen P; Esko T; Fav茅 MJ; Franke L; Frayling T; Gharib S; Gibson G; Hemani G; Jansen R; K盲h枚nen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg-Guzman J; Kukushkina V; Kutalik Z; Lee B; Lehtim盲ki T; Loeffler M; Marigorta UM; Metspalu A; Milani L; M眉ller-Nurasyid M; Nauck M; Nivard M; Penninx B; Perola M; Pervjakova N; Pierce B; Powell J; Prokisch H; Psaty B; Raitakari O; Ring S; Ripatti S; Rotzschke O; Ru毛ger S; Saha A; Scholz M; Schramm K; Sepp盲l盲 I; Stumvoll M; Sullivan P; Teumer A; Thiery J; Tong L; T枚njes A; Van Dongen J; Van Meurs J; Verlouw J; V枚lker U; V玫sa U; Yaghootkar H; Zeng B; Marioni RE; Montgomery GW; Deary IJ; Wray NR; Visscher PM; McRae AF; Yang J, 2018, 'Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood', Nature Communications, 9,
    Journal articles | 2018
    Qiao Z; Powell JE; Evans DM, 2018, 'MHC-dependent mate selection within 872 spousal pairs of european ancestry from the Health and Retirement Study', Genes, 9,
    Journal articles | 2018
    Ramnath D; Irvine K; Lukowski S; Horsfall L; Loh K; Clouston A; Patel P; Iyer A; Lampe G; Stow J; Schroder K; Fairlie D; Powell J; Powell E; Sweet M, 2018, 'RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease', Journal of Hepatology, 68, pp. S401 - S402,
    Journal articles | 2018
    Ramnath D; Irvine KM; Lukowski SW; Horsfall LU; Loh Z; Clouston AD; Patel PJ; Fagan KJ; Iyer A; Lampe G; Stow JL; Schroder K; Fairlie DP; Powell JE; Powell EE; Sweet MJ, 2018, 'Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes', Jci Insight, 3,
    Journal articles | 2018
    Wray NR; Ripke S; Mattheisen M; Trzaskowski M; Byrne EM; Abdellaoui A; Adams MJ; Agerbo E; Air TM; Andlauer TMF; Bacanu SA; B忙kvad-Hansen M; Beekman AFT; Bigdeli TB; Binder EB; Blackwood DRH; Bryois J; Buttensch酶n HN; Bybjerg-Grauholm J; Cai N; Castelao E; Christensen JH; Clarke TK; Coleman JIR; Colodro-Conde L; Couvy-Duchesne B; Craddock N; Crawford GE; Crowley CA; Dashti HS; Davies G; Deary IJ; Degenhardt F; Derks EM; DIrek N; Dolan CV; Dunn EC; Eley TC; Eriksson N; Escott-Price V; Kiadeh FHF; Finucane HK; Forstner AJ; Frank J; Gaspar HA; Gill M; Giusti-Rodr铆guez P; Goes FS; Gordon SD; Grove J; Hall LS; Hannon E; Hansen CS; Hansen TF; Herms S; Hickie IB; Hoffmann P; Homuth G; Horn C; Hottenga JJ; Hougaard DM; Hu M; Hyde CL; Ising M; Jansen R; Jin F; Jorgenson E; Knowles JA; Kohane IS; Kraft J; Kretzschmar WW; Krogh J; Kutalik Z; Lane JM; Li Y; Li Y; Lind PA; Liu X; Lu L; MacIntyre DJ; MacKinnon DF; Maier RM; Maier W; Marchini J; Mbarek H; McGrath P; McGuffin P; Medland SE; Mehta D; Middeldorp CM; Mihailov E; Milaneschi Y; Milani L; Mill J; Mondimore FM; Montgomery GW; Mostafavi S; Mullins N; Nauck M; Ng B, 2018, 'Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression', Nature Genetics, 50, pp. 668 - 681,
    Journal articles | 2018
    Xue A; Wu Y; Zhu Z; Zhang F; Kemper KE; Zheng Z; Yengo L; Lloyd-Jones LR; Sidorenko J; Wu Y; Agbessi M; Ahsan H; Alves I; Andiappan A; Awadalla P; Battle A; Beutner F; Bonder MJ; Boomsma D; Christiansen M; Claringbould A; Deelen P; Esko T; Fav茅 MJ; Franke L; Frayling T; Gharib S; Gibson G; Hemani G; Jansen R; K盲h枚nen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg-Guzman J; Kukushkina V; Kutalik Z; Lee B; Lehtim盲ki T; Loeffler M; Marigorta UM; Metspalu A; Milani L; M眉ller-Nurasyid M; Nauck M; Nivard M; Penninx B; Perola M; Pervjakova N; Pierce B; Powell J; Prokisch H; Psaty B; Raitakari O; Ring S; Ripatti S; Rotzschke O; Ru毛ger S; Saha A; Scholz M; Schramm K; Sepp盲l盲 I; Stumvoll M; Sullivan P; Teumer A; Thiery J; Tong L; T枚njes A; van Dongen J; van Meurs J; Verlouw J; V枚lker U; V玫sa U; Yaghootkar H; Zeng B; McRae AF; Visscher PM; Zeng J; Yang J, 2018, 'Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes', Nature Communications, 9,
    Journal articles | 2018
    Yap CX; Lloyd-Jones L; Holloway A; Smartt P; Wray NR; Gratten J; Powell JE, 2018, 'Trans-eQTLs identified in whole blood have limited influence on complex disease biology', European Journal of Human Genetics, 26, pp. 1361 - 1368,
    Journal articles | 2018
    Zeng J; De Vlaming R; Wu Y; Robinson MR; Lloyd-Jones LR; Yengo L; Yap CX; Xue A; Sidorenko J; McRae AF; Powell JE; Montgomery GW; Metspalu A; Esko T; Gibson G; Wray NR; Visscher PM; Yang J, 2018, 'Signatures of negative selection in the genetic architecture of human complex traits', Nature Genetics, 50, pp. 746 - 753,
    Journal articles | 2017
    Fung JN; Girling JE; Lukowski SW; Sapkota Y; Wallace L; Holdsworth-Carson SJ; Henders AK; Healey M; Rogers PAW; Powell JE; Montgomery GW, 2017, 'The genetic regulation of transcription in human endometrial tissue', Human Reproduction, 32, pp. 893 - 904,
    Journal articles | 2017
    Lloyd-Jones LR; Holloway A; McRae A; Yang J; Small K; Zhao J; Zeng B; Bakshi A; Metspalu A; Dermitzakis M; Gibson G; Spector T; Montgomery G; Esko T; Visscher PM; Powell JE, 2017, 'Erratum: The Genetic Architecture of Gene Expression in Peripheral Blood (American Journal of Human Genetics (2017) 100(2) (228鈥237)(S0002929716305328)(10.1016/j.ajhg.2016.12.008)', American Journal of Human Genetics, 100, pp. 371,
    Journal articles | 2017
    Lloyd-Jones LR; Holloway A; McRae A; Yang J; Small K; Zhao J; Zeng B; Bakshi A; Metspalu A; Dermitzakis M; Gibson G; Spector T; Montgomery G; Esko T; Visscher PM; Powell JE, 2017, 'The Genetic Architecture of Gene Expression in Peripheral Blood', American Journal of Human Genetics, 100, pp. 228 - 237,
    Journal articles | 2017
    Lukowski SW; Lloyd-Jones LR; Holloway A; Kirsten H; Hemani G; Yang J; Small K; Zhao J; Metspalu A; Dermitzakis ET; Gibson G; Spector TD; Thiery J; Scholz M; Montgomery GW; Esko T; Visscher PM; Powell JE, 2017, 'Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood', Nature Communications, 8,
    Journal articles | 2017
    Nayler SP; Powell JE; Vanichkina DP; Korn O; Wells CA; Kanjhan R; Sun J; Taft RJ; Lavin MF; Wolvetang EJ, 2017, 'Human iPSC-derived cerebellar neurons from a patient with ataxia-telangiectasia reveal disrupted gene regulatory networks', Frontiers in Cellular Neuroscience, 11,
    Journal articles | 2017
    Robins C; McRae AF; Powell JE; Wiener HW; Aslibekyan S; Kennedy EM; Absher DM; Arnett DK; Montgomery GW; Visscher PM; Cutler DJ; Conneely KN, 2017, 'Testing two evolutionary theories of human aging with DNA methylation data', Genetics, 207, pp. 1547 - 1560,
    Journal articles | 2017
    Zeng B; Lloyd-Jones LR; Holloway A; Marigorta UM; Metspalu A; Montgomery GW; Esko T; Brigham KL; Quyyumi AA; Idaghdour Y; Yang J; Visscher PM; Powell JE; Gibson G, 2017, 'Constraints on eQTL fine mapping in the presence of multisite local regulation of gene expression', G3 Genes Genomes Genetics, 7, pp. 2533 - 2544,
    Journal articles | 2016
    Gerring Z; Rodriguez-Acevedo AJ; Powell JE; Griffiths LR; Montgomery GW; Nyholt DR, 2016, 'Blood gene expression studies in migraine: Potential and caveats', Cephalalgia, 36, pp. 669 - 678,
    Journal articles | 2016
    Holdsworth-Carson SJ; Fung JN; Luong HTT; Sapkota Y; Bowdler LM; Wallace L; Teh WT; Powell JE; Girling JE; Healey M; Montgomery GW; Rogers PAW, 2016, 'Endometrial vezatin and its association with endometriosis risk', Human Reproduction, 31, pp. 999 - 1013,
    Journal articles | 2016
    Hung SSC; Chrysostomou V; Li F; Lim JKH; Wang JH; Powell JE; Tu L; Daniszewski M; Lo C; Wong RC; Crowston JG; P茅bay A; King AE; Bui BV; Liu GS; Hewitt AW, 2016, 'AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells in Vivo', Investigative Ophthalmology and Visual Science, 57, pp. 3470 - 3476,
    Journal articles | 2016
    Kassam I; Lloyd-Jones L; Holloway A; Small KS; Zeng B; Bakshi A; Metspalu A; Gibson G; Spector TD; Esko T; Montgomery GW; Powell JE; Yang J; Visscher PM; McRae AF, 2016, 'Autosomal genetic control of human gene expression does not differ across the sexes', Genome Biology, 17,
    Journal articles | 2016
    Kassam I; Qi T; Lloyd-Jones L; Holloway A; Bonder MJ; Henders AK; Martin NG; Powell JE; Franke L; Montgomery GW; Visscher PM; McRae AF, 2016, 'Evidence for mitochondrial genetic control of autosomal gene expression', Human Molecular Genetics, 25, pp. 5332 - 5338,
    Journal articles | 2016
    McKay FC; Gatt PN; Fewings N; Parnell GP; Schibeci SD; Basuki MAI; Powell JE; Goldinger A; Fabis-Pedrini MJ; Kermode AG; Burke T; Vucic S; Stewart GJ; Booth DR, 2016, 'The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies', Clinical Immunology, 163, pp. 96 - 107,
    Journal articles | 2016
    Pilling LC; Joehanes R; Kacprowski T; Peters M; Jansen R; Karasik D; Kiel DP; Harries LW; Teumer A; Powell J; Levy D; Lin H; Lunetta K; Munson P; Bandinelli S; Henley W; Hernandez D; Singleton A; Tanaka T; van Grootheest G; Hofman A; Uitterlinden AG; Biffar R; Gl盲ser S; Homuth G; Malsch C; V枚lker U; Penninx B; van Meurs JBJ; Ferrucci L; Kocher T; Murabito J; Melzer D, 2016, 'Gene transcripts associated with muscle strength: A CHARGE meta-analysis of 7,781 persons', Physiological Genomics, 48, pp. 1 - 11,
    Journal articles | 2016
    Powell JE; Fung JN; Shakhbazov K; Sapkota Y; Cloonan N; Hemani G; Hillman KM; Kaufmann S; Luong HT; Bowdler L; Painter JN; Holdsworth-Carson SJ; Visscher PM; Dinger ME; Healey M; Nyholt DR; French JD; Edwards SL; Rogers PAW; Montgomery GW, 2016, 'Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339', Human Molecular Genetics, 25, pp. 5046 - 5058,
    Journal articles | 2016
    Shakhbazov K; Powell JE; Hemani G; Henders AK; Martin NG; Visscher PM; Montgomery GW; McRae AF, 2016, 'Shared genetic control of expression and methylation in peripheral blood', BMC Genomics, 17,
    Journal articles | 2016
    Zhu Z; Zhang F; Hu H; Bakshi A; Robinson MR; Powell JE; Montgomery GW; Goddard ME; Wray NR; Visscher PM; Yang J, 2016, 'Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets', Nature Genetics, 48, pp. 481 - 487,
    Journal articles | 2015
    Benyamin B; Esko T; Ried JS; Radhakrishnan A; Vermeulen SH; Traglia M; G枚gele M; Anderson D; Broer L; Podmore C; Luan J; Kutalik Z; Sanna S; Van Der Meer P; Tanaka T; Wang F; Westra HJ; Franke L; Mihailov E; Milani L; H盲lldin J; Winkelmann J; Meitinger T; Thiery J; Peters A; Waldenberger M; Rendon A; Jolley J; Sambrook J; Kiemeney LA; Sweep FC; Sala CF; Schwienbacher C; Pichler I; Hui J; Demirkan A; Isaacs A; Amin N; Steri M; Waeber G; Verweij N; Powell JE; Nyholt DR; Heath AC; Madden PAF; Visscher PM; Wright MJ; Montgomery GW; Martin NG; Hernandez D; Bandinelli S; Van Der Harst P; Uda M; Vollenweider P; Scott RA; Langenberg C; Wareham NJ; Van Duijn C; Beilby J; Pramstaller PP; Hicks AA; Ouwehand WH; Oexle K; Gieger C; Metspalu A; Camaschella C; Toniolo D; Swinkels DW; Whitfield JB, 2015, 'Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis', Nature Communications, 6,
    Journal articles | 2015
    Gibson G; Powell JE; Marigorta UM, 2015, 'Expression quantitative trait locus analysis for translational medicine', Genome Medicine, 7,
    Journal articles | 2015
    Goldinger A; Shakhbazov K; Henders AK; McRae AF; Montgomery GW; Powell JE, 2015, 'Seasonal effects on gene expression', Plos One, 10,
    Journal articles | 2015
    McGovern AE; Driessen AK; Simmons DG; Powell J; Davis-Poynter N; Farrell MJ; Mazzone SB, 2015, 'Distinct brainstem and forebrain circuits receiving tracheal sensory neuron inputs revealed using a novel conditional anterograde transsynaptic viral tracing system', Journal of Neuroscience, 35, pp. 7041 - 7055,
    Journal articles | 2015
    Peters MJ; Joehanes R; Pilling LC; Schurmann C; Conneely KN; Powell J; Reinmaa E; Sutphin GL; Zhernakova A; Schramm K; Wilson YA; Kobes S; Tukiainen T; Ramos YF; G枚ring HHH; Fornage M; Liu Y; Gharib SA; Stranger BE; De Jager PL; Aviv A; Levy D; Murabito JM; Munson PJ; Huan T; Hofman A; Uitterlinden AG; Rivadeneira F; Van Rooij J; Stolk L; Broer L; Verbiest MMPJ; Jhamai M; Arp P; Metspalu A; Tserel L; Milani L; Samani NJ; Peterson P; Kasela S; Codd V; Peters A; Ward-Caviness CK; Herder C; Waldenberger M; Roden M; Singmann P; Zeilinger S; Illig T; Homuth G; Grabe HJ; V枚lzke H; Steil L; Kocher T; Murray A; Melzer D; Yaghootkar H; Bandinelli S; Moses EK; Kent JW; Curran JE; Johnson MP; Williams-Blangero S; Westra HJ; McRae AF; Smith JA; Kardia SLR; Hovatta I; Perola M; Ripatti S; Salomaa V; Henders AK; Martin NG; Smith AK; Mehta D; Binder EB; Nylocks KM; Kennedy EM; Klengel T; Ding J; Suchy-Dicey AM; Enquobahrie DA; Brody J; Rotter JI; Chen YDI; Houwing-Duistermaat J; Kloppenburg M; Slagboom PE; Helmer Q; Den Hollander W; Bean S; Raj T; Bakhshi N; Wang QP; Oyston LJ; Psaty BM; Tracy RP; Montgomery GW; Turner ST; Blangero J; Neely G, 2015, 'The transcriptional landscape of age in human peripheral blood', Nature Communications, 6, pp. 8570,
    Journal articles | 2015
    Robinson MR; Hemani G; Medina-Gomez C; Mezzavilla M; Esko T; Shakhbazov K; Powell JE; Vinkhuyzen A; Berndt SI; Gustafsson S; Justice AE; Kahali B; Locke AE; Pers TH; Vedantam S; Wood AR; Van Rheenen W; Andreassen OA; Gasparini P; Metspalu A; Van Den Berg LH; Veldink JH; Rivadeneira F; Werge TM; Abecasis GR; Boomsma DI; Chasman DI; De Geus EJC; Frayling TM; Hirschhorn JN; Hottenga JJ; Ingelsson E; Loos RJF; Magnusson PKE; Martin NG; Montgomery GW; North KE; Pedersen NL; Spector TD; Speliotes EK; Goddard ME; Yang J; Visscher PM, 2015, 'Population genetic differentiation of height and body mass index across Europe', Nature Genetics, 47, pp. 1357 - 1361,
    Journal articles | 2015
    Robinson PC; Claushuis TAM; Cortes A; Martin TM; Evans DM; Leo P; Mukhopadhyay P; Bradbury LA; Cremin K; Harris J; Maksymowych WP; Inman RD; Rahman P; Haroon N; Gensler L; Powell JE; Van Der Horst-Bruinsma IE; Hewitt AW; Craig JE; Lim LL; Wakefield D; McCluskey P; Voigt V; Fleming P; Degli-Esposti M; Pointon JJ; Weisman MH; Wordsworth BP; Reveille JD; Rosenbaum JT; Brown MA, 2015, 'Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis', Arthritis and Rheumatology, 67, pp. 140 - 151,
    Journal articles | 2014
    Benyamin B; Esko T; Ried JS; Radhakrishnan A; Vermeulen SH; Traglia M; G枚gele M; Anderson D; Broer L; Podmore C; Luan J; Kutalik Z; Sanna S; Van Der Meer P; Tanaka T; Wang F; Westra HJ; Franke L; Mihailov E; Milani L; H盲ldin J; Winkelmann J; Meitinger T; Thiery J; Peters A; Waldenberger M; Rendon A; Jolley J; Sambrook J; Kiemeney LA; Sweep FC; Sala CF; Schwienbacher C; Pichler I; Hui J; Demirkan A; Isaacs A; Amin N; Steri M; Waeber G; Verweij N; Powell JE; Nyholt DR; Heath AC; Madden PAF; Visscher PM; Wright MJ; Montgomery GW; Martin NG; Hernandez D; Bandinelli S; Van Der Harst P; Uda M; Vollenweider P; Scott RA; Langenberg C; Wareham NJ; Van Duijn C; Beilby J; Pramstaller PP; Hicks AA; Ouwehand WH; Oexle K; Gieger C; Metspalu A; Camaschella C; Toniolo D; Swinkels DW; Whitfield JB, 2014, 'Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis', Nature Communications, 5,
    Journal articles | 2014
    Hemani G; Shakhbazov K; Westra HJ; Esko T; Henders AK; McRae AF; Yang J; Gibson G; Martin NG; Metspalu A; Franke L; Montgomery GW; Visscher PM; Powell JE, 2014, 'Detection and replication of epistasis influencing transcription in humans', Nature, 508, pp. 249 - 253,
    Journal articles | 2014
    Hemani G; Shakhbazov K; Westra HJ; Esko T; Henders AK; McRae AF; Yang J; Gibson G; Martin NG; Metspalu A; Franke L; Montgomery GW; Visscher PM; Powell JE, 2014, 'Hemani et al. reply', Nature, 514, pp. E5 - E6,
    Journal articles | 2014
    McKenzie M; Henders AK; Caracella A; Wray NR; Powell JE, 2014, 'Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood', BMC Medical Genomics, 7,
    Journal articles | 2014
    McRae AF; Powell JE; Henders AK; Bowdler L; Hemani G; Shah S; Painter JN; Martin NG; Visscher PM; Montgomery GW, 2014, 'Contribution of genetic variation to transgenerational inheritance of DNA methylation', Genome Biology, 15, pp. R73,
    Journal articles | 2014
    Parnell GP; Gatt PN; McKay FC; Schibeci S; Krupa M; Powell JE; Visscher PM; Montgomery GW; Lechner-Scott J; Broadley S; Liddle C; Slee M; Vucic S; Stewart GJ; Booth DR, 2014, 'Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season', Multiple Sclerosis Journal, 20, pp. 675 - 685,
    Journal articles | 2014
    Ripke S; Neale BM; Corvin A; Walters JTR; Farh KH; Holmans PA; Lee P; Bulik-Sullivan B; Collier DA; Huang H; Pers TH; Agartz I; Agerbo E; Albus M; Alexander M; Amin F; Bacanu SA; Begemann M; Belliveau RA; Bene J; Bergen SE; Bevilacqua E; Bigdeli TB; Black DW; Bruggeman R; Buccola NG; Buckner RL; Byerley W; Cahn W; Cai G; Campion D; Cantor RM; Carr VJ; Carrera N; Catts SV; Chambert KD; Chan RCK; Chen RYL; Chen EYH; Cheng W; Cheung EFC; Chong SA; Cloninger CR; Cohen D; Cohen N; Cormican P; Craddock N; Crowley JJ; Curtis D; Davidson M; Davis KL; Degenhardt F; Del Favero J; Demontis D; Dikeos D; Dinan T; Djurovic S; Donohoe G; Drapeau E; Duan J; Dudbridge F; Durmishi N; Eichhammer P; Eriksson J; Escott-Price V; Essioux L; Fanous AH; Farrell MS; Frank J; Franke L; Freedman R; Freimer NB; Friedl M; Friedman JI; Fromer M; Genovese G; Georgieva L; Giegling I; Giusti-Rodr铆guez P; Godard S; Goldstein JI; Golimbet V; Gopal S; Gratten J; De Haan L; Hammer C; Hamshere ML; Hansen M; Hansen T; Haroutunian V; Hartmann AM; Henskens FA; Herms S; Hirschhorn JN; Hoffmann P; Hofman A; Hollegaard MV; Hougaard DM; Ikeda M; Joa I; Powell J, 2014, 'Biological insights from 108 schizophrenia-associated genetic loci', Nature, 511, pp. 421 - 427,
    Journal articles | 2014
    Wood AR; Esko T; Yang J; Vedantam S; Pers TH; Gustafsson S; Chu AY; Estrada K; Luan J; Kutalik Z; Amin N; Buchkovich ML; Croteau-Chonka DC; Day FR; Duan Y; Fall T; Fehrmann R; Ferreira T; Jackson AU; Karjalainen J; Lo KS; Locke AE; M盲gi R; Mihailov E; Porcu E; Randall JC; Scherag A; Vinkhuyzen AAE; Westra HJ; Winkler TW; Workalemahu T; Zhao JH; Absher D; Albrecht E; Anderson D; Baron J; Beekman M; Demirkan A; Ehret GB; Feenstra B; Feitosa MF; Fischer K; Fraser RM; Goel A; Gong J; Justice AE; Kanoni S; Kleber ME; Kristiansson K; Lim U; Lotay V; Lui JC; Mangino M; Leach IM; Medina-Gomez C; Nalls MA; Nyholt DR; Palmer CD; Pasko D; Pechlivanis S; Prokopenko I; Ried JS; Ripke S; Shungin D; Stanc谩kov谩 A; Strawbridge RJ; Sung YJ; Tanaka T; Teumer A; Trompet S; Van Der Laan SW; Van Setten J; Van Vliet-Ostaptchouk JV; Wang Z; Yengo L; Zhang W; Afzal U; 脛rnl枚v J; Arscott GM; Bandinelli S; Barrett A; Bellis C; Bennett AJ; Berne C; Bl眉her M; Bolton JL; B枚ttcher Y; Boyd HA; Bruinenberg M; Buckley BM; Buyske S; Caspersen IH; Chines PS; Clarke R; Claudi-Boehm S; Cooper M; Daw EW; De Jong PA; Deelen J; Delgado G, 2014, 'Defining the role of common variation in the genomic and biological architecture of adult human height', Nature Genetics, 46, pp. 1173 - 1186,
    Journal articles | 2013
    Goldinger A; Henders AK; McRae AF; Martin NG; Gibson G; Montgomery GW; Visscher PM; Powell JE, 2013, 'Genetic and nongenetic variation revealed for the principal components of human gene expression', Genetics, 195, pp. 1117 - 1128,
    Journal articles | 2013
    Hemani G; Yang J; Vinkhuyzen A; Powell JE; Willemsen G; Hottenga JJ; Abdellaoui A; Mangino M; Valdes AM; Medland SE; Madden PA; Heath AC; Henders AK; Nyholt DR; De Geus EJC; Magnusson PKE; Ingelsson E; Montgomery GW; Spector TD; Boomsma DI; Pedersen NL; Martin NG; Visscher PM, 2013, 'Inference of the genetic architecture underlying bmi and height with the use of 20,240 sibling pairs', American Journal of Human Genetics, 93, pp. 865 - 875,
    Journal articles | 2013
    Luong HTT; Painter JN; Shakhbazov K; Chapman B; Henders AK; Powell JE; Nyholt DR; Montgomery GW, 2013, 'Fine mapping of variants associated with endometriosis in the WNT4 region on chromosome 1p36', International Journal of Molecular Epidemiology and Genetics, 4, pp. 193 - 206
    Journal articles | 2013
    Pardo V; Knuth D; McDermott B; Powell J; Goldberg A, 2013, 'Validity, reliability and minimum detectable change of the maximum step length test in people with stroke', JOURNAL OF THE NEUROLOGICAL SCIENCES, 325, pp. 74 - 78,
    Journal articles | 2013
    Powell JE; Henders AK; McRae AF; Kim J; Hemani G; Martin NG; Dermitzakis ET; Gibson G; Montgomery GW; Visscher PM, 2013, 'Congruence of Additive and Non-Additive Effects on Gene Expression Estimated from Pedigree and SNP Data', Plos Genetics, 9,
    Journal articles | 2013
    Revez JA; Bain L; Chapman B; Powell JE; Jansen R; Duffy DL; Tung JY; Collaborators AAGC; Matheson MC; Marks GB; Hui J; Le Sou毛f P; Danoy P; Baltic S; Nyholt DR; Jenkins M; Hayden C; Beilby J; Cheah F; Madden PA; Heath AC; Hopper JL; Musk B; Leeder SR; Walters EH; James A; Jones G; Abramson MJ; Robertson CF; Dharmage SC; Brown MA; Thompson PJ; Penninx BW; Visscher PM; De Geus EJC; Boomsma DI; Hinds DA; Martin NG; Montgomery GW; Ferreira MAR, 2013, 'A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk', Genes and Immunity, 14, pp. 441 - 446,
    Journal articles | 2013
    Westra HJ; Peters MJ; Esko T; Yaghootkar H; Schurmann C; Kettunen J; Christiansen MW; Fairfax BP; Schramm K; Powell JE; Zhernakova A; Zhernakova DV; Veldink JH; Van Den Berg LH; Karjalainen J; Withoff S; Uitterlinden AG; Hofman A; Rivadeneira F; Hoen PAC; Reinmaa E; Fischer K; Nelis M; Milani L; Melzer D; Ferrucci L; Singleton AB; Hernandez DG; Nalls MA; Homuth G; Nauck M; Radke D; V枚lker U; Perola M; Salomaa V; Brody J; Suchy-Dicey A; Gharib SA; Enquobahrie DA; Lumley T; Montgomery GW; Makino S; Prokisch H; Herder C; Roden M; Grallert H; Meitinger T; Strauch K; Li Y; Jansen RC; Visscher PM; Knight JC; Psaty BM; Ripatti S; Teumer A; Frayling TM; Metspalu A; Van Meurs JBJ; Franke L, 2013, 'Systematic identification of trans eQTLs as putative drivers of known disease associations', Nature Genetics, 45, pp. 1238 - 1243,
    Journal articles | 2012
    Gordon L; Joo JE; Powell JE; Ollikainen M; Novakovic B; Li X; Andronikos R; Cruickshank MN; Conneely KN; Smith AK; Alisch RS; Morley R; Visscher PM; Craig JM; Saffery R, 2012, 'Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence', Genome Research, 22, pp. 1395 - 1406,
    Journal articles | 2012
    Powell JE; Henders AK; McRae AF; Caracella A; Smith S; Wright MJ; Whitfield JB; Dermitzakis ET; Martin NG; Visscher PM; Montgomery GW, 2012, 'The Brisbane systems genetics study: Genetical genomics meets complex trait genetics', Plos One, 7,
    Journal articles | 2012
    Powell JE; Henders AK; McRae AF; Wright MJ; Martin NG; Dermitzakis ET; Montgomery GW; Visscher PM, 2012, 'Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent', Genome Research, 22, pp. 456 - 466,
    Journal articles | 2012
    Powell JE; Kranis A; Floyd J; Dekkers JCM; Knott S; Haley CS, 2012, 'Optimal use of regression models in genome-wide association studies', Animal Genetics, 43, pp. 133 - 143,
    Journal articles | 2012
    Yang J; Loos RJF; Powell JE; Medland SE; Speliotes EK; Chasman DI; Rose LM; Thorleifsson G; Steinthorsdottir V; M盲gi R; Waite L; Vernon Smith A; Yerges-Armstrong LM; Monda KL; Hadley D; Mahajan A; Li G; Kapur K; Vitart V; Huffman JE; Wang SR; Palmer C; Esko T; Fischer K; Hua Zhao J; Demirkan A; Isaacs A; Feitosa MF; Luan J; Heard-Costa NL; White C; Jackson AU; Preuss M; Ziegler A; Eriksson J; Kutalik Z; Frau F; Nolte IM; Van Vliet-Ostaptchouk JV; Hottenga JJ; Jacobs KB; Verweij N; Goel A; Medina-Gomez C; Estrada K; Bragg-Gresham JL; Sanna S; Sidore C; Tyrer J; Teumer A; Prokopenko I; Mangino M; Lindgren CM; Assimes TL; Shuldiner AR; Hui J; Beilby JP; McArdle WL; Hall P; Haritunians T; Zgaga L; Kolcic I; Polasek O; Zemunik T; Oostra BA; Juhani Junttila M; Gr枚nberg H; Schreiber S; Peters A; Hicks AA; Stephens J; Foad NS; Laitinen J; Pouta A; Kaakinen M; Willemsen G; Vink JM; Wild SH; Navis G; Asselbergs FW; Homuth G; John U; Iribarren C; Harris T; Launer L; Gudnason V; O'Connell JR; Boerwinkle E; Cadby G; Palmer LJ; James AL; Musk AW; Ingelsson E; Psaty BM; Beckmann JS; Waeber G; Vollenweider P; Hayward C; Wright AF; Rudan I, 2012, 'FTO genotype is associated with phenotypic variability of body mass index', Nature, 490, pp. 267 - 273,
    Journal articles | 2011
    Maugeri N; Powell JE; 't Hoen PAC; de Geus EJC; Willemsen G; Kattenberg M; Henders AK; Wallace L; Penninx B; Hottenga JJ; Medland SE; Saviouk V; Martin NG; Visscher PM; van Ommen GJB; Frazer IH; Boomsma DI; Montgomery GW; Ferreira MAR, 2011, 'LPAR1 and ITGA4 regulate peripheral blood monocyte counts', Human Mutation, 32, pp. 873 - 876,
    Journal articles | 2011
    McEvoy BP; Powell JE; Goddard ME; Visscher PM, 2011, 'Human population dispersal "Out of Africa" estimated from linkage disequilibrium and allele frequencies of SNPs', Genome Research, 21, pp. 821 - 829,
    Journal articles | 2011
    Powell JE; Zietsch BP, 2011, 'Predicting sensation seeking from dopamine genes: Use and misuse of genetic prediction', Psychological Science, 22, pp. 413 - 415,
    Journal articles | 2010
    Powell JE; Visscher PM; Goddard ME, 2010, 'Reconciling the analysis of IBD and IBS in complex trait studies', Nature Reviews Genetics, 11, pp. 800 - 805,
    Journal articles | 2009
    Lam AC; Powell J; Wei W-H; de Koning D-J; Haley CS, 2009, 'A combined strategy for quantitative trait loci detection by genome-wide association.', BMC Proc, 3 Suppl 1, pp. S6,
    Journal articles | 2008
    Powell J; White I; Guy D; Brotherstone S, 2008, 'Genetic parameters of production traits in Atlantic salmon (Salmo salar)', Aquaculture, 274, pp. 225 - 231,
    Journal articles | 1997
    Bourinbaiar AS; Powell JE; Stevens VC, 1997, 'The role of carboxy-terminal portion of beta subunit of human chorionic gonadotropin in human immunodeficiency virus infection', LIFE SCIENCES, 61, pp. PL149 - PL157,
    Journal articles | 1988
    WILSON MJ; SINHA AA; POWELL JEH; ESTENSEN RD, 1988, 'PLASMINOGEN-ACTIVATOR ACTIVITIES IN THE DEVELOPING RAT PROSTATE', BIOLOGY OF REPRODUCTION, 38, pp. 723 - 731,
    Journal articles | 1986
    DOMINGUE GJ; ACEVEDO HF; POWELL JE; STEVENS VC, 1986, 'ANTIBODIES TO BACTERIAL VACCINES DEMONSTRATING SPECIFICITY FOR HUMAN CHORIOGONADOTROPIN (HCG) AND IMMUNOCHEMICAL DETECTION OF HCG-LIKE FACTOR IN SUBCELLULAR BACTERIAL FRACTIONS', INFECTION AND IMMUNITY, 53, pp. 95 - 98,
    Journal articles | 1986
    RAIKOW RB; ACEVEDO HF; POWELL JE; STEVENS VC; FOGARTY PA; ANDINO VW, 1986, 'HUMORAL RESPONSE OF NORMAL AND ATHYMIC (NUDE) MICE TO HUMAN CHORIOGONADOTROPIN IMMUNOGENS', AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY AND MICROBIOLOGY, 12, pp. 99 - 102
    Journal articles | 1986
    STEVENS VC; CHOU WS; POWELL JE; LEE AC; SMOOT J, 1986, 'THE IDENTIFICATION OF PEPTIDE SEQUENCES OF HUMAN CHORIONIC-GONADOTROPIN CONTAINING A CONFORMATIONAL EPITOPE', IMMUNOLOGY LETTERS, 12, pp. 11 - 18,
    Journal articles | 1985
    CARAUX J; CHICHEHIAN B; GESTIN C; LONGHI B; LEE AC; POWELL JE; STEVENS VC; POURQUIER A, 1985, 'NON-CROSS-REACTIVE MONOCLONAL-ANTIBODIES TO HUMAN CHORIONIC-GONADOTROPIN GENERATED AFTER IMMUNIZATION WITH A SYNTHETIC PEPTIDE', JOURNAL OF IMMUNOLOGY, 134, pp. 835 - 840
    Journal articles | 1981
    OKAMURA K; POWELL JE; LEE AC; STEVENS VC, 1981, 'CHARACTERIZATION OF SOLUBILIZED MICROVILLOUS MEMBRANE-PROTEINS AND GLYCOPROTEINS FROM HUMAN PLACENTAL SYNCYTIOTROPHOBLAST', PLACENTA, 2, pp. 117 - 128,
    Journal articles | 1981
    STEVENS VC; CINADER B; POWELL JE; LEE AC; KOH SW, 1981, 'PREPARATION AND FORMULATION OF A HUMAN CHORIONIC-GONADOTROPIN ANTIFERTILITY VACCINE - SELECTION OF A PEPTIDE IMMUNOGEN', AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1, pp. 307 - 314,
    Journal articles | 1981
    STEVENS VC; CINADER B; POWELL JE; LEE AC; KOH SW, 1981, 'PREPARATION AND FORMULATION OF A HUMAN CHORIONIC-GONADOTROPIN ANTIFERTILITY VACCINE - SELECTION OF ADJUVANT AND VEHICLE', AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1, pp. 315 - 321,
    Journal articles | 1981
    STEVENS VC; POWELL JE; LEE AC; GRIFFIN D, 1981, 'ANTI-FERTILITY EFFECTS OF IMMUNIZATION OF FEMALE BABOONS WITH C-TERMINAL PEPTIDES OF THE BETA-SUBUNIT OF HUMAN CHORIONIC-GONADOTROPIN', FERTILITY AND STERILITY, 36, pp. 98 - 105
    Journal articles | 1980
    LEE ACJ; POWELL JE; TREGEAR GW; NIALL HD; STEVENS VC, 1980, 'A METHOD FOR PREPARING BETA-HCG COOH PEPTIDE-CARRIER CONJUGATES OF PREDICTABLE COMPOSITION', MOLECULAR IMMUNOLOGY, 17, pp. 749 - 756,
    Journal articles | 1980
    MATSUURA S; OHASHI M; CHEN HC; SHOWNKEEN RC; STOCKELLHARTREE A; REICHERT LE; STEVENS VC; POWELL JE, 1980, 'PHYSICOCHEMICAL AND IMMUNOLOGICAL CHARACTERIZATION OF AN HCG-LIKE SUBSTANCE FROM HUMAN PITUITARY-GLANDS', NATURE, 286, pp. 740 - 741,
    Journal articles | 1980
    POWELL JE; LEE AC; TREGEAR GW; NIALL HD; STEVENS VC, 1980, 'CHARACTERISTICS OF ANTIBODIES RAISED TO CARBOXY-TERMINAL PEPTIDES OF HCG BETA-SUBUNIT', JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2, pp. 1 - 13,
    Journal articles | 1970
    HANSON FW; POWELL JE; STEVENS VC, 1970, 'FOLLICLE-STIMULATING HORMONE LEVELS DURING PREGNANCY', OBSTETRICS AND GYNECOLOGY, 36, pp. 667 - &,
    Journal articles | 1970
    HANSON FW; POWELL JE; TRELFORD JD, 1970, 'POSTPARTUM FSH LEVELS - REPORT OF 2 CASES', OBSTETRICS AND GYNECOLOGY, 35, pp. 462 - &,
  • Working Papers | 2020
    Du Q; Smith G; Luu PL; Ferguson J; Armstrong N; Caldon E; Campbell E; Nair S; Zotenko E; Gould C; Buckley M; Kaczorowski D; Barton K; Deveson I; Smith M; Powell J; Skvortsova K; Stirzaker C; Achinger-Kawecka J; Clark S, 2020, DNA methylation is required to maintain DNA replication timing precision and 3D genome integrity,
  • Preprints | 2026
    Pa膷ar I; Ungaro MT; Chen Y; Dallali H; Medico JA; Hebbar P; Diekhans M; Di Tommaso E; Geleta M; Chan PP; Lowe TM; Balacco J; Jain N; Ackerman F; Mochi M; Ioannidis AG; Sawarkar N; Diaz K; Krishna Sudhakar K; Powell JE; Jain M; Rosa A; Croft GF; Tanzer A; Jarvis ED; Formenti G; Salama SR; Giunta S, 2026, The diploid reference genome of a human embryonic stem cell line.,
    Preprints | 2025
    Cuomo ASE; Spenceley E; Tanudisastro H; Bowen B; Henry A; Huang HL; Xue A; Zhou W; Welland M; Bryen S; Dong O; Lee A; Pullin J; Wing K; Tang O; Gray M; Franklin M; Harper M; Silk M; Bobowik K; Stuckey A; Marshall J; Bakiris V; Uren C; Madala BS; Miniter A; Bartie C; Neavin D; Qiao Z; Ben-David E; Chen L; Farh KK-H; Grieve S; Nguyen T; Wallace C; Piscionere J; Siggs O; Nicholas H; de Lange K; Hewitt A; Figtree G; MacArthur D; Powell J, 2025, Impact of rare and common genetic variation on cell type-specific gene expression in human blood,
    Preprints | 2025
    Hall JC; Sudhakar KK; Daniszewski M; Senabouth A; Abbott CJ; Liang HH; Kumar H; Lidgerwood GE; Mirzaei M; Ma J; Atkeson T; Hirokawa Y; Nandrot EF; Barnett A; Cazevieille C; Manes G; Mountford S; Thompson P; Fletcher EL; Wu Z; Bahlo M; Ansell BRE; Paull D; Hewitt AW; Guymer RH; Powell JE; P茅bay A, 2025, Patient induced pluripotent stem cells identify specificities of a reticular pseudodrusen phenotype in age-related macular degeneration,
    Preprints | 2025
    Henry A; Senabouth A; Tyebally R; Bowen B; Allen PC; Spenceley E; Sagi-Zsigmond E; Cuomo ASE; Fan J; Huang HL; Tanudisastro HA; Xue A; de Lange KM; Figtree GA; Hewitt AW; MacArthur DG; Powell JE, 2025, Single-cell genetics identifies cell type-specific causal mechanisms in complex traits and diseases,
    Preprints | 2025
    Lee WE; Cook SL; Purvis GSD; Henry A; Schnitzler K; Genetzakis E; Besnier M; Chandrakanthan M; Tran A; Strbenac D; Mifsud C; Bate K; Vernon ST; Nguyen TV; Gray MP; Grieve SM; Yang J; MacArthur D; Powell JE; Channon KM; Douglas G; Figtree GA, 2025, Endothelial Colony-Forming Cell Transcriptomic Profiling in CT-defined Coronary Artery Disease from the BioHEART-CT Study Implicate CCBE1 in Mitochondrial Dysfunction-associated Atherosclerosis,
    Conference Abstracts | 2025
    Lim JWY; Keith P; McCloy R; Neavin D; Spenceley E; Xu A; Sudhakar KK; Bowen B; Suan D; Mehta A; Joshua AM; Chin V; Powell J, 2025, 'A polygenic risk score to predict immunotherapy toxicity: A pilot single-cell RNA sequencing study', in ANNALS OF ONCOLOGY, ELSEVIER, Vol. 36,
    Preprints | 2025
    Maksimovic J; Shanthikumar S; Howitt G; Dixit G; Hickey PF; Anttila C; Brown DV; Gubbels L; Senabouth A; Amann-Zalcenstein D; Powell JE; Ranganathan SC; Oshlack A; Neeland MR, 2025, Single-cell profiling of BAL in preschool cystic fibrosis reveals macrophage dysregulation and ivacaftor-modified inflammatory programs in the early life lung,
    Preprints | 2025
    Meng A; Yuile A; Sim H-W; Thavaneswaran S; Noor H; Yeung J; Mehta A; Powell J; Zaman A, 2025, A Systematic Review and Meta-Analysis of the Impact of Tumour Mutation Burden on Survival Outcomes in Solid Tumours,
    Preprints | 2025
    Sopena-Rios M; Ripoll-Cladellas A; Omidi F; Ballouz S; Alquicira-Hernandez J; Oelen R; Franke L; Wijst MVD; Powell J, 2025, Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence,
    Preprints | 2025
    Tanudisastro HA; Cuomo ASE; Weisburd B; Welland M; Spenceley E; Franklin M; Xue A; Bowen B; Wing K; Tang O; Gray M; Reis ALM; Margoliash J; Kurtas NE; Pullin JM; Lee AS; Brand H; Harper M; Bobowik K; Silk M; Marshall J; Bakiris V; Madala BS; Uren C; Bartie C; Senabouth A; Dashnow H; Fearnley L; Martin-Trujillo A; Dolzhenko E; Qiao Z; Grieve SM; Nguyen T; Ben-David E; Chen L; Farh KK-H; Talkowski M; Alexander SI; Siggs OM; Gruenschloss L; Nicholas HR; Piscionere J; Simons C; Wallace C; Gymrek M; Deveson IW; Hewitt AW; Figtree GA; de Lange KM; Powell JE; MacArthur DG, 2025, Polymorphic tandem repeats influence cell type-specific gene expression across the human immune landscape.,
    Preprints | 2025
    Wilson SB; Vanslambrouck JM; Murphy A; Neavin DR; Powell JE; Howden SE; Little MH, 2025, Classification of indeterminate and off-target cell types within human kidney organoid differentiation,
    Preprints | 2025
    Xue A; Fan J; Dong O; Huang HL; Allen P; Spenceley E; Sagi-Zsigmond E; Bowen B; Cuomo ASE; Henry A; Tanudisastro H; Qiao Z; Chen L; Ben-David E; Farh KK-H; Neavin D; Lee A; Senabouth A; Bartie C; McCloy R; Chin V; de Lange K; Figtree G; Hewitt A; MacArthur D; Powell J, 2025, Genetic regulation of cell type鈥搒pecific chromatin accessibility shapes immune function and disease risk,
    Preprints | 2025
    Yazar S; Alquicira-Hernandez J; Wing K; Senabouth A; Andersen S; Fairfax KA; Hewitt AW; Powell JE; Ballouz S, 2025, The impact of sex on the immune system explored at the single-cell level,
    Preprints | 2025
    Zhou Y; Adeluwa T; Zhu L; Salazar-Maga帽a S; Sumner S; Kim H; Gona S; Nyasimi F; Kulkarni R; Powell J; Madduri R; Liu B; Chen M; Im HK, 2025, scPrediXcan integrates advances in deep learning and single-cell data into a powerful cell-type-specific transcriptome-wide association study framework.,
    Preprints | 2024
    Chai RC; Lundberg M; Freudenthal B; Smith JT; Boughton AP; Zhang Y; Flynn KA; Frysz M; Corr AP; Khoo WH; Komla-Ebri D; Dack MRG; Guilfoyle SE; Logan JG; Butterfield NC; Leitch VD; Pollard AS; M盲kitie RE; McDonald MM; Youlten SE; Sergio CM; Evans DM; Powell JE; de Leeuw CA; Ewing AD; Eisman JA; Blank RD; Phan TG; Baldock PA; Duncan EL; Williams GR; Bassett JHD; Croucher PI; Kemp JP, 2024, Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease,
    Conference Abstracts | 2024
    Chin V; McCloy RA; Sennabouth A; Neavin D; Arora H; Boyer M; Simes J; Joshua A; Brown B; Powell J, 2024, 'P1.03D.09 Single Cell RNA Sequencing and Functional Monocyte Stimulation Reveals Phenotypic Predispositions to Developing Lung Cancer in Never Smokers', in Journal of Thoracic Oncology, Elsevier BV, Vol. 19, pp. S155 - S156,
    Preprints | 2024
    Chin VT; Muskovic W; McCloy RA; Neavin DR; Alquicira-Hernandez J; Arora H; Senabouth A; Keith P; Spenceley E; Murphy A; Kaczorowski D; Floros P; Earls P; Leavers B; Crawford J; Gallagher R; Powell JE, 2024, Protein Translation Dysregulation and Immune Cell Evasion Define Metastatic Clones in HPV-related Cancer of the Oropharynx,
    Conference Abstracts | 2024
    Dsouza R; Skarne N; Mulay O; Harris L; Holton E; Zaman A; Akgul S; Offenhauser C; Alexander H; Lwin Z; Jeffree R; Inglis P-L; Powell J; Nguyen Q; Boyd A; Day B, 2024, 'EXTH-10. TARGETING EPHA3 AND EPHRIN A5: ADVANCED PRECISION THERAPY FOR GBM', in Neuro-Oncology, Oxford University Press (OUP), Vol. 26, pp. viii238 - viii238,
    Conference Abstracts | 2024
    Lim JWY; Chin VT; Keith P; McCloy R; Neavin D; Xue A; Kaczorowski D; Spenceley E; Arora H; Joshua AM; Powell J, 2024, 'Predicting immunotherapy toxicity through single-cell sequencing of peripheral immune cells: A pilot study.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 42, pp. e14538 - e14538,
    Preprints | 2024
    Muskovic W; Zaman A; Pandya M; Holton E; Chan C-L; McCloy RA; Arora H; Chin VT; Powell JE, 2024, Adult-type diffuse gliomas share recurring cell states driven by a common astrocyte-like glioma stem cell population,
    Preprints | 2024
    Neely G; Loo L; Fujikake K; Saad S; Clark T; Hamoudi Z; Manion J; Caron L; Davis O; Tavares-Ferreira D; Shiers S; Powell J; Price T, 2024, Spinal signatures of entrenched and treated neuropathic pain,
    Preprints | 2024
    Sopena-Rios M; Ripoll-Cladellas A; Omidi F; Ballouz S; Hernandez JA; Oelen R; Franke L; van der Wijst MGP; Powell JE; Mel茅 M, 2024, Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence,
    Preprints | 2024
    Xue A; Yazar S; Alquicira-Hern谩ndez J; Cuomo A; Senabouth A; Gordon G; Kathail P; Ye CJ; Hewitt A; Powell J, 2024, Genetic variants associated with cell-type-specific intra-individual gene expression variability reveal new mechanisms of genome regulation,
    Conference Abstracts | 2024
    Zaman A; Muskovic W; Holton E; Pandya M; Zakanovic R; Chin V; Lam E; Yeung J; Sughrue M; Teo C; Powell J, 2024, 'A BRAIN CANCER CELL ATLAS REVEALS SHARED ASTROCYTE-LIKE STEM CELL STATES DRIVE INTRATUMOURAL HETEROGENEITY AND SHAPE IMMUNE DYNAMICS IN ADULT-TYPE DIFFUSE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Glasgow, Vol. 26, pp. V3 - V3, presented at 19th Meeting of the European-Association-of-Neuro-Oncology (EANO), ENGLAND, Glasgow, 17 October 2024 - 20 October 2024,
    Conference Abstracts | 2024
    Zaman A; Muskovic W; Holton E; Pandya M; Zekanovic R; Chin V; Lam E; Moutinho C; Yeung J; Teo C; Sughrue M; Powell J, 2024, 'STEM-01. SHARED ASTROCYTE-LIKE GLIOMA STEM CELLS DRIVE HETEROGENEITY AND IMMUNE DYNAMICS IN ADULT-TYPE DIFFUSE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 26, pp. viii57 - viii57,
    Conference Papers | 2024
    Zhang L-Y; Apte S; Lutzky V; Groves P; Tan M; de Silva TA; Nguyen Q; Powell J; Chambers D; O'Sullivan B, 2024, 'Cellular Genomics of Bronchoalveolar Lavage Reveals Insight into Mechanisms of Human Pulmonary Fibrosis', in A72. EPITHELIAL CELLS: KEY CULPRITS IN PULMONARY FIBROSIS, American Thoracic Society, pp. A2580 - A2580, presented at American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA,
    Preprints | 2024
    Zhou W; Cuomo ASE; Xue A; Kanai M; Chau G; Krishna C; Xavier RJ; MacArthur DG; Powell JE; Daly MJ; Neale BM, 2024, Efficient and accurate mixed model association tool for single-cell eQTL analysis.,
    Conference Papers | 2023
    Ballinger ML; Pattnaik S; Mundra PA; Zaheed M; Rath E; Priestley P; Baber J; Ray-Coquard I; Isambert N; Causeret S; van der Graaf WTA; Puri A; Duffaud F; Le Cesne A; Seddon B; Chandrasekar C; Schiffman JD; Brohl AS; James PA; Kurtz JE; Penel N; Myklebost O; Meza-Zepeda LA; Pickett H; Kansara M; Waddell N; Kondrashova O; Pearson JV; Barbour AP; Li S; Nguyen TL; Fatkin D; Graham RM; Giannoulatou E; Green MJ; Kaplan W; Ravishankar S; Copty J; Powell JE; Cuppen E; van Eijk K; Veldink J; Ahn JH; Kim JE; Lor Randall R; Tucker K; Judson I; Sarin R; Ludwig T; Genin E; Deleuze JF; Haber M; Marshall G; Cairns MJ; Blay JY; Thomas DM, 2023, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', in Science, WILEY, pp. 253 - 260,
    Conference Abstracts | 2023
    Chin V; Arora H; Alquicira-Hernandez J; Sennabouth A; McCloy R; Simes J; Boyer M; Hogg P; Young J; Joshua A; Brown B; Powell J, 2023, 'Single cell RNA sequencing reveals phenotypic predispositions to developing lung cancer in neversmokers', in RESPIROLOGY, WILEY, Vol. 28, pp. 13 - 13,
    Conference Papers | 2023
    Cuomo A; de Lange K; MacArthur D; Powell J; Hewitt A, 2023, 'Uncovering context-specific and dynamic genetic regulation of gene expression in immune cells at single-cell resolution', in EUROPEAN JOURNAL OF HUMAN GENETICS, SPRINGERNATURE, SCOTLAND, Glasgow, pp. 666 - 666, presented at 56th Annual Conference of the European-Society-of-Human-Genetics (ESHG), SCOTLAND, Glasgow, 10 June 2023 - 13 June 2023
    Preprints | 2023
    Greatbatch C; Lu Q; Hung S; Tran S; Wing K; Liang H; Han X; Zhou T; Siggs O; Mackey D; Liu G-S; Cook A; Powell J; Craig J; MacGregor S; Hewitt A, 2023, Deep Learning-based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell and Organelle Morphology,
    Preprints | 2023
    Greatbatch CJ; Lu Q; Hung S; Wing K; Liang H; Han X; Zhou T; Siggs OM; Mackey DA; Cook AL; Senabouth A; Liu G-S; Craig JE; MacGregor S; Powell JE; Hewitt AW, 2023, High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma,
    Preprints | 2023
    Kang JB; Shen AZ; Sakaue S; Luo Y; Gurajala S; Nathan A; Rumker L; Aguiar VRC; Valencia C; Lagattuta K; Zhang F; Jonsson AH; Yazar S; Alquicira-Hernandez J; Khalili H; Ananthakrishnan AN; Jagadeesh K; Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network ; Daly MJ; Xavier RJ; Donlin LT; Anolik JH; Powell JE; Rao DA; Brenner MB; Gutierrez-Arcelus M; Raychaudhuri S, 2023, Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.,
    Preprints | 2023
    Rumker L; Sakaue S; Reshef Y; Kang JB; Yazar S; Alquicira-Hernandez J; Valencia C; Lagattuta KA; Mah-Som A; Nathan A; Powell JE; Loh P-R; Raychaudhuri S, 2023, Identifying genetic variants that influence the abundance of cell states in single-cell data.,
    Preprints | 2023
    Wang T; Harvey K; Reeves J; Roden DL; Bartonicek N; Yang J; Al-Eryani G; Kaczorowski D; Chan C-L; Powell J; O鈥橳oole S; Lim E; Swarbrick A, 2023, An experimental comparison of the Digital Spatial Profiling and Visium spatial transcriptomics technologies for cancer research,
    Preprints | 2022
    Grimm L; Mason E; Yu O; Dudczig S; Panara V; Chen T; Bower NI; Paterson S; Okuda K; Galeano MR; Kobayashi S; Senabouth A; Lagendijk AK; Powell J; Smith KA; Koltowska K; Hogan BM, 2022, Single cell analysis of lymphatic endothelial cell fate specification and differentiation during zebrafish development,
    Preprints | 2022
    Luecken M; Sikkema L; Strobl D; Zappia L; Madissoon E; Markov N; Zaragosi L-E; Ansari M; Arguel M-J; Apperloo L; Becavin C; Berg M; Chichelnitskiy E; Chung M-I; Collin A; Gay A; Kashani BH; Jain M; Kapellos T; Kole T; Mayr C; von Papen M; Peter L; Ram铆rez-Su谩stegui C; Schniering J; Taylor C; Walzthoeni T; Xu C; Bui L; de Donno C; Dony L; Guo M; Gutierrez A; Heumos L; Huang N; R铆o IID; Jackson N; Murthy PKL; Lotfollahi M; Tabib T; Talavera-Lopez C; Travaglini K; Wilbrey-Clark A; Worlock K; Yoshida M; Desai T; Rozenblatt-Rosen O; Falk C; Kaminski N; Krasnow M; Lafyatis R; Nikolic M; Powell J; Rajagopal J; Seibold M; Sheppard D; Shepherd D; Teichmann S; Tsankov A; Whitsett J; Xu Y; Banovich N; Barbry P; Duong T; Meyer K; Kropski J; Pe'er D; Schiller H; Tata PR; Schultze J; Berge MVD; Chen Y; Hagood J; Hassan A; Horvath P; Lundeberg J; Leroy S; Marquette C; Pryhuber G; Samakovlis C; Sun X; Ware L; Zhang K; Misharin A; Nawijn M; Theis F, 2022, An integrated cell atlas of the human lung in health and disease,
    Preprints | 2022
    Maksimovic J; Shanthikumar S; Howitt G; Hickey PF; Ho W; Anttila C; Brown DV; Senabouth A; Kaczorowski D; Amann-Zalcenstein D; Powell JE; Ranganathan SC; Oshlack A; Neeland MR, 2022, Single-cell atlas of bronchoalveolar lavage from preschool cystic fibrosis reveals new cell phenotypes,
    Preprints | 2022
    Neavin D; Senabouth A; Hang Lee JT; Ripoll A; Franke L; Prabhakar S; Ye CJ; McCarthy DJ; Mel茅 M; Hemberg M; Powell JE, 2022, Demuxafy : Improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods,
    Preprints | 2022
    Shen S; Werner T; Lukowski SW; Andersen S; Sun Y; Shim WJ; Mizikovsky D; Kobayashi S; Outhwaite J; Chiu HS; Chen X; Chapman G; Martin EMMA; Xia D; Pham D; Su Z; Kim D; Yang P; Tan MC; Sinniah E; Zhao Q; Negi S; Redd MA; Powell JE; Dunwoodie SL; Tam PPL; Bod茅n M; Ho JWK; Nguyen Q; Palpant NJ, 2022, A pluripotent stem cell atlas of multilineage differentiation reveals TMEM88 as a developmental regulator of mammalian blood pressure,
    Preprints | 2022
    Sikkema L; Strobl D; Zappia L; Madissoon E; Markov NS; Zaragosi L; Ansari M; Arguel M; Apperloo L; B茅cavin C; Berg M; Chichelnitskiy E; Chung M; Collin A; Gay ACA; Hooshiar Kashani B; Jain M; Kapellos T; Kole TM; Mayr C; von Papen M; Peter L; Ram铆rez-Su谩stegui C; Schniering J; Taylor C; Walzthoeni T; Xu C; Bui LT; de Donno C; Dony L; Guo M; Gutierrez AJ; Heumos L; Huang N; Ibarra I; Jackson N; Kadur Lakshminarasimha Murthy P; Lotfollahi M; Tabib T; Talavera-Lopez C; Travaglini K; Wilbrey-Clark A; Worlock KB; Yoshida M; Desai T; Eickelberg O; Falk C; Kaminski N; Krasnow M; Lafyatis R; Nikol铆c M; Powell J; Rajagopal J; Rozenblatt-Rosen O; Seibold MA; Sheppard D; Shepherd D; Teichmann SA; Tsankov A; Whitsett J; Xu Y; Banovich NE; Barbry P; Duong TE; Meyer KB; Kropski JA; Pe鈥檈r D; Schiller HB; Tata PR; Schultze JL; Misharin AV; Nawijn MC; Luecken MD; Theis F, 2022, An integrated cell atlas of the human lung in health and disease,
    Conference Abstracts | 2022
    Thomas DM, 2022, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', in CANCER SCIENCE, WILEY, Vol. 113,
    Preprints | 2022
    Xue A; Yazar S; Neavin D; Powell J, 2022, Pitfalls and opportunities for applying PEER factors in single-cell eQTL analyses,
    Preprints | 2021
    Daniszewski M; Senabouth A; Liang H; Han X; Lidgerwood G; Hern谩ndez D; Sivakumaran P; Clarke J; Lim S; Lees J; Rooney L; Gulluyan L; Souzeau E; Graham S; Chan C-L; Nguyen U; Farbehi N; Gnanasambandapillai V; McCloy R; Clarke L; Kearns L; Mackey D; Craig J; MacGregor S; Powell J; P茅bay A; Hewitt A, 2021, Retinal ganglion cell-specific genetic regulation in primary open angle glaucoma,
    Preprints | 2021
    Muskovic W; Powell JE, 2021, DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data,
    Preprints | 2021
    Neavin DR; Steinmann AM; Chiu HS; Daniszewski MS; Moutinho C; Chan C-L; Tyebally M; Gnanasambandapillai V; Lam CE; Nguyen U; Hern谩ndez D; Lidgerwood GE; Hewitt AW; P茅bay A; Palpant NJ; Powell JE, 2021, Village in a dish: a model system for population-scale hiPSC studies,
    Preprints | 2021
    Patel B; Kleeman SO; Neavin D; Powell J; Baskozos G; Ng M; Ahmed W-U-R; Bennett DL; Schmid A; Furniss D; Wiberg A, 2021, DIRC3-IGFBP5 is a shared genetic risk locus and therapeutic target for carpal tunnel syndrome and trigger finger,
    Preprints | 2021
    Phipson B; Sim CB; Porrello ER; Hewitt AW; Powell J; Oshlack A, 2021, propeller : testing for differences in cell type proportions in single cell data,
    Preprints | 2021
    Senabouth A; Daniszewski M; Lidgerwood G; Liang H; Hern谩ndez D; Mirzaei M; Zhang R; Han X; Neavin D; Rooney L; Sanchez IL; Gulluyan L; Paulo J; Clarke L; Kearns L; Gnanasambandapillai V; Chan C-L; Nguyen U; Steinmann A; Zekanovic R; Farbehi N; Gupta V; Mackey D; Bylsma G; Verma N; MacGregor S; Guymer R; Powell J; Hewitt A; P茅bay A, 2021, Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration,
    Preprints | 2021
    Talenti A; Powell J; Hemmink JD; Cook EAJ; Wragg D; Jayaraman S; Paxton E; Ezeasor C; Obishakin ET; Agusi ER; Tijjani A; Marshall K; Fisch A; Ferreira B; Qasim A; Chaudhry UN; Wiener P; P. T; Morrison LJ; Connelley T; Prendergast J, 2021, A cattle graph genome incorporating global breed diversity,
    Preprints | 2021
    Wilson SB; Howden SE; Vanslambrouck JM; Dorison A; Alquicira-Hernandez J; Powell JE; Little MH, 2021, DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets,
    Preprints | 2020
    Alquicira-Hernandez J; Powell JE; Phan TG, 2020, No evidence that plasmablasts transdifferentiate into developing neutrophils in severe COVID-19 disease,
    Preprints | 2020
    Alquicira-Hernandez J; Powell JE, 2020, Nebulosa recovers single cell gene expression signals by kernel density estimation,
    Preprints | 2020
    Cobos FA; Alquicira-Hernandez J; Powell J; Mestdagh P; De Preter K, 2020, Comprehensive benchmarking of computational deconvolution of transcriptomics data,
    Preprints | 2020
    Engel JA; Lee HJ; Williams CG; Kuns R; Olver S; Lansink LIM; Soon MSF; Andersen SB; Powell JE; Svensson V; Teichmann SA; Hill GR; Varelias A; Koyama M; Haque A, 2020, Single-cell transcriptomics of allo-reactive CD4 + T cells over time reveals divergent fates during gut GVHD,
    Preprints | 2020
    Neavin D; Nguyen Q; Daniszewski MS; Liang HH; Chiu HS; Senabouth A; Lukowski SW; Crombie DE; Lidgerwood GE; Hern谩ndez D; Vickers JC; Cook AL; Palpant NJ; P茅bay A; Hewitt AW; Powell JE, 2020, Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells,
    Preprints | 2020
    Nieto P; Elosua-Bayes M; Trincado JL; Marchese D; Massoni-Badosa R; Salvany M; Henriques A; Mereu E; Moutinho C; Ruiz S; Lorden P; Chin VT; Kaczorowski D; Chan C-L; Gallagher R; Chou A; Planas-Rigol E; Rubio-Perez C; Gut I; Piulats JM; Seoane J; Powell JE; Batlle E; Heyn H, 2020, A Single-Cell Tumor Immune Atlas for Precision Oncology,
    Preprints | 2020
    Wu S; Roden D; Al-Eryani G; Bartonicek N; Harvey K; Cazet A; Chan C-L; Junankar S; Hui M; Millar E; Beretov J; Horvath L; Joshua A; Stricker P; Wilmott J; Quek C; Long G; Scolyer R; Yeung B; Segara D; Mak C; Warrier S; Powell J; O'Toole S; Lim E; Swarbrick A, 2020, Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis,
    Preprints | 2020
    Wu S; Roden D; Wang C; Holliday H; Harvey K; Cazet A; Murphy K; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy J; Junankar S; Chan C-L; Lam E; Hui M; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O鈥橳oole S; Cox T; Timpson P; Lim E; Liu S; Swarbrick A, 2020, Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer,
    Conference Abstracts | 2019
    Chin VT; Al Eryani G; McCloy R; Stone E; Havryk A; Plit M; Field A; Watkins N; Swarbrick A; Powell J, 2019, 'Using single cell genomics to change the treatment of lung cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019,
    Preprints | 2019
    Lidgerwood GE; Senabouth A; Smith-Anttila CJA; Gnanasambandapillai V; Kaczorowski DC; Amann-Zalcenstein D; Fletcher EL; Naik SH; Hewitt AW; Powell JE; P茅bay A, 2019, Transcriptomic Profiling of Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Over Time,
    Preprints | 2019
    Senabouth A; Andersen S; Shi Q; Shi L; Liu P; Jiang F; Zhang W; Wing K; Daniszewski M; Lukowski SW; Hung SSC; Nguyen Q; Fink L; Beckhouse A; Jiang H; P茅bay A; Hewitt AW; Powell JE, 2019, Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing,
    Preprints | 2019
    Wang H; Zhang F; Zeng J; Wu Y; Kemper KE; Xue A; Zhang M; Powell JE; Goddard ME; Wray NR; Visscher PM; McRae AF; Yang J, 2019, Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank,
    Preprints | 2019
    Xu J; Falconer C; Nguyen Q; Crawford J; McKinnon BD; Mortlock S; P茅bay A; Hewitt AW; Senabouth A; Andersen S; Palpant N; Chiu HS; Montgomery GW; Powell J; Coin L, 2019, Genotype-free demultiplexing of pooled single-cell RNA-seq,
    Preprints | 2019
    van der Wijst MGP; de Vries DH; Groot HE; Trynka G; Hon C-C; Nawijn MC; Idaghdour Y; van der Harst P; Ye CJ; Powell J; Theis FJ; Mahfouz A; Heinig M; Franke L, 2019, Single-cell eQTLGen Consortium: a personalized understanding of disease,
    Preprints | 2018
    Alquicira-Hern谩ndez J; Sathe A; Ji HP; Nguyen Q; Powell JE, 2018, scPred: Cell type prediction at single-cell resolution,
    Preprints | 2018
    De Smit E; Lukowski SW; Anderson L; Senabouth A; Dauyey K; Song S; Wyse B; Wheeler L; Chen CY; Cao K; Yuen AWT; Shuey N; Clarke L; Sanchez IL; Hung SSC; P茅bay A; Mackey DA; Brown MA; Hewitt AW; Powell JE, 2018, Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent Giant Cell Arteritis,
    Preprints | 2018
    Lukowski SW; Lo CY; Sharov A; Nguyen QH; Fang L; Hung SSC; Zhu L; Zhang T; Nguyen T; Senabouth A; Jabbari JS; Welby E; Sowden JC; Waugh HS; Mackey A; Pollock G; Lamb TD; Wang P-Y; Hewitt AW; Gillies M; Powell JE; Wong RCB, 2018, Generation of human neural retina transcriptome atlas by single cell RNA sequencing,
    Preprints | 2018
    Pinese M; Lacaze P; Rath E; Stone A; Brion M-J; Ameur A; Nagpal S; Puttick C; Husson S; Degrave D; Navin Cristina T; Silva Kahl V; Statham A; Woods R; McNeil J; Riaz M; Barr M; Nelson M; Reid C; Murray A; Shah R; Wolfe R; Atkins J; Fitzsimmons C; Cairns H; Green M; Carr V; Cowley M; Pickett H; James P; Powell J; Kaplan W; Gibson G; Gyllensten U; Cairns M; McNamara M; Dinger M; Thomas D, 2018, The Medical Genome Reference Bank: Whole genomes and phenotype of 2,570 healthy elderly,
    Preprints | 2018
    V玫sa U; Claringbould A; Westra H-J; Bonder MJ; Deelen P; Zeng B; Kirsten H; Saha A; Kreuzhuber R; Kasela S; Pervjakova N; Alvaes I; Fave M-J; Agbessi M; Christiansen M; Jansen R; Sepp盲l盲 I; Tong L; Teumer A; Schramm K; Hemani G; Verlouw J; Yaghootkar H; S枚nmez R; Brown A; Kukushkina V; Kalnapenkis A; R眉eger S; Porcu E; Kronberg-Guzman J; Kettunen J; Powell J; Lee B; Zhang F; Arindrarto W; Beutner F; Brugge H; Dmitreva J; Elansary M; Fairfax BP; Georges M; Heijmans BT; K盲h枚nen M; Kim Y; Knight JC; Kovacs P; Krohn K; Li S; Loeffler M; Marigorta UM; Mei H; Momozawa Y; M眉ller-Nurasyid M; Nauck M; Nivard M; Penninx B; Pritchard J; Raitakari O; Rotzchke O; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; Hoen PACT; Thiery J; T枚njes A; van Dongen J; van Iterson M; Veldink J; V枚lker U; Wijmenga C; Swertz M; Andiappan A; Montgomery GW; Ripatti S; Perola M; Kutalik Z; Dermitzakis E; Bergmann S; Frayling T; van Meurs J; Prokisch H; Ahsan H; Pierce B; Lehtim盲ki T; Boomsma D; Psaty BM; Gharib SA; Awadalla P; Milani L; Ouwehand W; Downes K; Stegle O; Battle A; Yang J; Visscher PM; Scholz M; Gibson G; Esko T; Franke L, 2018, Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis,
    Preprints | 2017
    Daniszewski M; Senabouth A; Nguyen Q; Crombie DE; Lukowski SW; Kulkarni T; Zack DJ; P茅bay A; Powell JE; Hewitt AW, 2017, Single Cell RNA Sequencing of stem cell-derived retinal ganglion cells,
    Preprints | 2017
    Friedman C; Nguyen Q; Lukowski S; Chiu HS; Helfer A; Miklas J; Suo SS; Jackie Han J-D; Osteil P; Peng G; Jing N; Baillie G; Senabouth A; Christ A; Bruxner T; Murry C; Wong E; Ding J; Wang Y; Hudson J; Ruohola-Baker H; Bar-Joseph Z; Tam P; Powell J; Palpant N, 2017, Analysis of cardiac differentiation at single cell resolution reveals a requirement of hypertrophic signaling for HOPX transcription,
    Preprints | 2017
    McRae AF; Marioni RE; Shah S; Yang J; Powell JE; Harris SE; Gibson J; Henders AK; Bowdler L; Painter JN; Murphy L; Martin NG; Starr JM; Wray NR; Deary IJ; Visscher PM; Montgomery GW, 2017, Identification of 55,000 Replicated DNA Methylation QTL,
    Conference Papers | 2017
    Montgomery GW; Fung JN; Holdsworth-Carson SJ; Girling JE; Franch JD; Edwards SL; Powell JE; Rogers PAW, 2017, 'Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.', in REPRODUCTIVE SCIENCES, SAGE PUBLICATIONS INC, FL, Orlando, pp. 272A - 272A, presented at 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), FL, Orlando, 15 March 2017 - 18 March 2017,
    Preprints | 2017
    Nguyen QH; Lukowski SW; Chiu HS; Friedman CE; Senabouth A; Crowhurst L; Bruxmer TJC; Christ AN; Palpant NJ; Powell JE, 2017, Determining cell fate specification and genetic contribution to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution,
    Preprints | 2017
    Nguyen QH; Lukowski SW; Chiu HS; Senabouth A; Bruxner TJC; Christ AN; Palpant NJ; Powell JE, 2017, Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations,
    Preprints | 2017
    Senabouth A; Lukowski SW; Alquicira Hernandez J; Andersen S; Mei X; Nguyen QH; Powell JE, 2017, ascend : R package for analysis of single cell RNA-seq data,
    Preprints | 2017
    Wong E; Chenoweth S; Blows M; Powell J, 2017, Evidence for stabilizing selection at pleiotropic loci for human complex traits,
    Preprints | 2017
    Zeng J; de Vlaming R; Wu Y; Robinson MR; Lloyd-Jones L; Yengo L; Yap C; Xue A; Sidorenko J; McRae AF; Powell JE; Montgomery GW; Metspalu A; Esko T; Gibson G; Wray NR; Visscher PM; Yang J, 2017, Widespread signatures of negative selection in the genetic architecture of human complex traits,
    Conference Papers | 2016
    De Smit E; Clarke L; Ngygen K; Shuey N; Hill C; Anderson L; Evans D; Brown MA; Powell J; Hewitt AW, 2016, 'LONGITUDINAL EXPRESSION PROFILING OF T LYMPHOCYTES IN PATIENTS WITH ACTIVE TO QUIESCENT GIANT CELL ARTERITIS', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY-BLACKWELL, pp. 99 - 100
    Preprints | 2016
    Hung SSC; Chrysostomou V; Li F; Lim JKH; Wang J-H; Powell JE; Tu L; Daniszewski M; Lo C; Wong RC; Crowston JG; P茅bay A; King AE; Bui BV; Liu G-S; Hewitt AW, 2016, AAV-mediated CRISPR/Cas gene editing of retinal cells in vivo,
    Preprints | 2016
    Zeng B; Lloyd-Jones LR; Holloway A; Marigorta UM; Metspalu A; Montgomery GW; Esko T; Brigham KL; Quyyumi AA; Idaghdour Y; Yang J; Visscher PM; Powell JE; Gibson G, 2016, Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression,
    Conference Papers | 2015
    McKay F; Gatt PN; Fewings N; Schibeci SD; Parnell G; Basuki MAI; Powell JE; Goldinger A; Fabis-Pedrini MJ; Kermode AG; Burke T; Vucic S; Stewart GJ; Booth DR, 2015, 'Characterising the Molecular Phenotypes of MS: heredity, gene expression modules, dysregulated immune cell subsets and response to therapy', in MULTIPLE SCLEROSIS JOURNAL, SAGE PUBLICATIONS LTD, AUSTRALIA, Melbourne, pp. NP3 - NP4, presented at MS Research Australia Progress in MS Research Conference, AUSTRALIA, Melbourne, 29 October 2015 - 30 October 2015,
    Conference Papers | 2013
    Ebejer J; Medland S; Martin NG; Wright M; Montgomery G; Powell J; Visscher P; Duffy D, 2013, 'Clarification of varying genetic expression and structure within adolescent monozygotic and dizygotic twins discordant for high and low attention and activity', in BEHAVIOR GENETICS, SPRINGER, FRANCE, Marseille, pp. 515 - 516, presented at 43rd Annual Meeting of the Behavior-Genetics-Association, FRANCE, Marseille, 28 June 2013 - 02 July 2013
    Conference Papers | 2012
    Medland S; Verweij K; Powell J, 2012, 'Using openMx for GWAS', in BEHAVIOR GENETICS, SPRINGER, SCOTLAND, Edinburgh, pp. 952 - 952, presented at 42nd Annual Meeting of the Behavior-Genetics-Association, SCOTLAND, Edinburgh, 22 June 2012 - 25 June 2012
    Conference Papers | 2004
    Powell JH; Pickering AD; Dawkins L; West R; Powell JF, 2004, 'Cognitive and psychological correlates of smoking abstinence, and predictors of successful cessation', in ADDICTIVE BEHAVIORS, PERGAMON-ELSEVIER SCIENCE LTD, AUSTRALIA, Queensland, pp. 1407 - 1426, presented at Conference on Crossing Boundaries - Implications of Advances in Basic Sciences for the Management of Addiction, AUSTRALIA, Queensland,
    Conference Papers | 1989
    STEVENS VC; POWELL JE; RICKEY M; LEE AC; LEWIS DH, 1989, 'STUDIES OF VARIOUS DELIVERY SYSTEMS FOR A HUMAN CHORIONIC-GONADOTROPIN VACCINE', in ALEXANDER NJ; GRIFFIN D; SPIELER JM; WAITES GMH (eds.), GAMETE INTERACTION, WILEY-LISS, INC, ARGENTINA, SAN CARLOS BARILOCHE, pp. 549 - 563, presented at 3RD INTERNATIONAL WORKSHOP OF THE CONTRACEPTIVE RESEARCH AND DEVELOPMENT PROGRAM - GAMETE INTERACTION : PROSPECTS FOR IMMUNOCONTRACEPTION, ARGENTINA, SAN CARLOS BARILOCHE, 26 November 1989 - 29 November 1989,
    Conference Papers | 1986
    SINHA AA; ESTENSEN RD; POWELL JEH; WILSON MJ, 1986, 'PLASMINOGEN-ACTIVATOR ACTIVITIES IN THE DEVELOPING RAT PROSTATE', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 267 - 267,
    Conference Papers | 1984
    CARAUX J; CHICHEHIAN B; GESTIN C; LONGHI B; LEE AC; POWELL JE, 1984, 'UNCROSSREACTIVE MONOCLONAL-ANTIBODIES TO HUMAN CHORIONIC-GONADOTROPIN GENERATED AFTER IMMUNIZATION WITH A SYNTHETIC PEPTIDE IMMUNOGEN', in SCANDINAVIAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, pp. 169 - 169,
    Conference Papers | 1971
    STEVENS VC; POWELL JE; SPARKS SJ, 1971, 'EFFECTS OF PASSIVE IMMUNIZATIONS WITH ANTISERA AGAINST HUMAN PLACENTAL LACTOGEN ON GESTATION IN BABOON', in BIOLOGY OF REPRODUCTION, SOC STUDY REPRODUCTION, pp. 97 - &,
    Preprints |
    Daniszewski M; Nguyen Q; Chy H; Singh V; Crombie D; Kulkarni T; Liang H; Lidgerwood G; Hernnndez D; Conquest A; Rooney L; Chevalier S; Andersen S; Senabouth A; Vickers J; Mackey D; Craig J; Laslett A; Hewitt A; Powell JE; PPbay A, Single Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media,
    Preprints |
    Friedman CE; Nguyen Q; Lukowski SW; Helfer A; Chiu HS; Voges HK; Suo Suo S; Jackie Han J-D; Osteil P; Peng G; Jing N; Baillie GJ; Senabouth A; Christ AN; Bruxner TJ; Murry CE; Wong ES; Ding J; Wang Y; Hudson J; Bar-Joseph Z; Tam PPL; Powell JE; Palpant NJ, Cardiac Directed Differentiation Using Small Molecule WNT Modulation at Single-Cell Resolution,
    Preprints |
    Tuong ZK; Lukowski SW; Nguyen QH; Chandra J; Zhou C; Gillinder K; Bashaw AA; Ferdinand JR; Stewart BJ; Teoh SM; Hanson SJ; Devitt K; Clatworthy MR; Powell JE; Frazer IH, A Model of Impaired Langerhans Cell Maturation Associated With HPV Induced Epithelial Hyperplasia,