Dr Jennifer Snaith
Conjoint Senior Lecturer
FRACP, MBBS (Hons), BMedSci, PhD听
Medicine & Health
School of Clinical Medicine
Dr Jennifer Snaith is an Endocrinologist and post-doctoral scientist based at the Victor Chang Cardiac Research Institute where she conducts clinical trials in type 1 diabetes as co-lead of the ACT-T1D research group (Australian Collaborative Towards Adjunctive Therapies in Type 1 Diabetes) together with Professor Jerry Greenfield. Her career mission is to improve the lives of people living with type 1 diabetes through clinical service, advocacy and innovative research.听
She is a Staff Specialist Endocrinologist at St Vincent's Hospital, and established with her team, the Diabetes in Youth (DIY) service in 2021. Her research activities are clinically based and relate to type 1 diabetes, insulin resistance, adjunctive therapies and cardiometabolic risk.
During her PhD candidature (primary supervisor Greenfield) Dr Snaith was awarded the Dean's Thesis Award for the INTIMET study (INsulin resistance in type 1 diabetes managed with METformin). She was the recipient of a National Health and Medical Research Council (NHMRC) Post Graduate Scholarship, and Diabetes Australia top up scholarship, and was awarded the Dean's Award for her thesis. The INTIMET study was a placebo controlled randomised controlled clinical examining the impact of metformin on hepatic and muscle insulin resistance, assessed using hyperinsulinaemic euglycaemic clamps. Publication:听https://doi.org/10.1038/s41467-025-65951-1听
The RESET1 study (Reducing Cardiometabolic Risk with Semaglutide in Type 1 Diabetes) is the second clinical trial from the ACT-T1D group. Dr Snaith was awarded the Diabetes Australia Coghlan Award for Emerging Researchers, and the Rebecca Davies Fellowship from Breakthrough T1D Australia to conduct this randomised placebo controlled clinical trial to examine the effect of semaglutide on cardiovascular risk in adults with type 1 diabetes. Trial registration:听https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=386649&isReview=true ; trial protocol: https://doi.org/10.1111/dme.15377听
The TIRTLE1 study (Tirzepatide in Type 1 Diabetes: Cardiometabolic Effects) was the first phase 2 placebo controlled trial assessing the effect of tirzepatide on weight in adults with in type 1 diabetes and obesity. Publication:听
The TIRTLE2 study is a mechanistic follow on study from TIRTLE1, designed to assess the acute metabolic effects of tirzepatide on insulin resistance in type 1 diabetes, supported by Breakthrough T1D (NCT06820281)
The ACT-T1D specialise in the conduct of clinical trials in type 1 diabetes. These studies include detailed mechanistic studies, to phenotype metabolic health in type 1 diabetes, and the physiological impacts of adjunctive therapies on cardiometabolic health in type 1 diabetes. Metabolic phenotypic capabilities include hyperinsulinaemic-euglycaemic clamps, hyperinsulinaemic-hypoglycaemic clamps, mixed meal tolerance tests, calorimetry, body composition measurement, arterial stiffness measures, and others.
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E-mail
- Publications
- Awards
- Grants
- Research Activities
- Engagement
- Teaching and Supervision
- Media
2025 -听St Vincent鈥檚 Healthcare Clinical Campus 2024 HDR Thesis Award for Greatest Clinical Impact
2024 - 91色情片 Dean's Award for Outstanding Thesis
2024 - Australian Diabetes Society Lindsey Baudinet Rising Star Award in Type 1 Diabetes Research
2023 - Diabetes Australia Coghlan Award, for project 'Reducing Cardiometabolic Risk with Semaglutide in Type 1 Diabetes (RESET1)'
2022 - JDRF Rebecca Davies Fellowship
2022 - Australian Diabetes Society Clinical Young Investigator's Award
2021 - 91色情片 ARC Postgraduate Council Research Student Award
2020 - 91色情片 Visualise Your Thesis (Runner Up)
2020听- NHMRC Post Graduate Scholarship
2020听- NHMRC/Diabetes Australia co-funding award
2019听- 91色情片 University Post Graduate Award听
2018 - Joan Waugh Scholarship for academic excellence and leadership potential
2018 - Westmead Association Tracey Robinson Registrar Award for Excellence in Teaching
2017 - Westmead Association Advanced Trainee of the Year
2015 - Westmead听Association Tracey Robinson Registrar Award for Excellence in Teaching
2007 - University of Sydney Exchange Scholarship
2005 - Medical Science Scholarship
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2025
- Breakthrough T1D $1.8M, Snaith JR (CI-A), Frampton R, Horowitz M, Jones K, Greenfield JR,听Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes (TIRTLE2)
- 听ADS Diabetes Research Seed Grant $20,000,听Sheu A, Snaith JR (CI-B), Greenfield JR,听Semaglutide and bone in T1D: defining skeletal-metabolic interactions in the RESET1 trial
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- St Vincent鈥檚 Clinic Foundation Annual Grant $50,000,听Snaith, JR (CI-A), Frampton R, Samocha-Bonet D, Greenfield JR, A Phase II study examining the effects of adjunctive tirzepatide on weight, metabolism and cardiovascular risk in adults with type 1 diabetes and obesity (the TIRTLE study)
- Australian Diabetes Society Lindsey Baudinet Rising Star in Type 1 Diabetes Award $20,000,听Snaith JR (CI-A), Towards combo therapy: Tirzepatide for weight, metabolism and CV risk in adults with T1D and obesity (a phase II trial)'.听
- MRFF 2023 TTRA 鈥 Cardiovascular Disease and Diabetes Mechanisms $916,315:听Greenfield JR, Snaith JR (CI-B), Repurposed Semaglutide to Bridge听the T1D听Cardiovascular Risk Gap
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2023听听听听听听听听听
- Diabetes Australia Coghlan Award $150,000,听Snaith JR (CI-A), Reducing Cardiometabolic Risk with Semaglutide in Type 1 Diabetes (RESET1)
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2022听听听听听听听听听
- JDRF Rebecca Davies Fellowship $142,500,听Snaith JR (CI-A), Reducing Cardiometabolic Risk with Semaglutide in Type 1 Diabetes (RESET1)
- University of New South Wales Infrastructure Grant $200,651,听听Samocha-Bonet D, Snaith JR (CI-B), Greenfield JR, Chen R, Danta M, Jabbour A, Lim E, Patel S. BodPod and Q-NRG for extensive metabolic phenotyping
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2021听听听听听听听听听
- St Vincent鈥檚 Curran Foundation Endowment Grant $10,930,听Snaith JR (CI-A), 鈥業ntroducing rapid point of care HbA1c (Haemoglobin A1c) tests to SVH diabetes clinics鈥
- Cardiac, Vascular and Metabolic Medicine Theme Networking Seed Grant $30,000,听Snaith JR (CI-A), Liu Z, Lovell N, Greenfield JR, 鈥楢 novel online tool to diagnose double diabetes using biomarkers: towards cardiovascular risk reduction by personalised adjunctive treatment of insulin resistance in type 1 diabetes鈥
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2020听听听听听听听听听
- St Vincent鈥檚 Clinic Foundation Tancred Grant $50,000,听Greenfield JR, Snaith J (CI-B), Holmes-Walker J, Girgis C, 鈥業NTIMET 鈥 Insulin Resistance in Type 1 Diabetes Managed with Metformin鈥
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2019
- Diabetes Australia Millennium Grant (Type 1 Diabetes) $150,000,听Greenfield JR, Snaith J (CI-B), Holmes Walker JR, Girgis C, Samocha-Bonet D, 鈥楶henotypic Characterisation of Insulin-Sensitive and Insulin-Resistant Adults with Type 1 Diabetes鈥
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My Research Supervision
91色情片 PhD
- Dr R.Frampton: The Incretin Signature and the Role of听Semaglutide in Type 1 Diabetes听
91色情片 Medicine Honours
- J.Yang: Repurposing Adjunctive Therapies in Type 1 Diabetes: A听Patient Experience Survey
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Previous research supervision:
91色情片 Medicine Honours (B.Lamaro):听 An Unmet Needs Assessment in Type 1 Diabetes Mellitius: Rationale for Adjunctive Therapies?
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