Dr Angelica Ly

Senior Lecturer

Associate Fellow, Higher Education Academy, 2023
Fellow, American Academy of Optometry, 2017
Doctor of Philosophy (Vision Science), 91ɫ��Ƭ Sydney, Thesis title: Multimodal imaging in age-related macular degeneration, 2018
Graduate Certificate in Ocular Therapeutics, 91ɫ��Ƭ Sydney, 2014
Bachelor of Optometry (Honours class 1), 91ɫ��Ƭ Sydney, 2008

Medicine & Health

School of Optometry and Vision Science

I am a Clinician-Scientist and Senior Lecturer at 91ɫ��Ƭ whose research and teaching focuses on closing the evidence‑to‑practice gap in posterior eye care, especially age-related macular degeneration.

My research refines imaging biomarkers, develops clinician-centred artificial intelligence and decision support, and applies knowledge translation to improve adoption of new technologies and health communication. This work enables more accurate frontline diagnosis, sharper prognostics, and system-level improvements so the right information reaches the right people at the right time.

PhD projects on offer (Jan 2026, to apply, send your CV to a.ly@unsw.edu.au)

Phone

61-2-93481384

E-mail

A.Ly@unsw.edu.au

Location

Room 3.059, Level 3 Rupert Myers Building (north wing) Gate 14 Barker St 91ɫ��Ƭ Sydney

Journal articles | 2026

Nam J; Lim C; Ly A; Herse S; Williams M-A; Stapleton F, 2026, 'Stakeholder Perspectives of Implementation Barriers of Artificial Intelligence in Eye Care: A qualitative framework-based study', Ophthalmic and Physiological Optics

Journal articles | 2025

Ly A; Herse S; Williams M-A; Stapleton F, 2025, 'Artificial Intelligence for Age-Related Macular Degeneration Diagnosis in Australia: A Novel Qualitative Interview Study', Ophthalmic and Physiological Optics,

Journal articles | 2025

Ly A; Hui A, 2025, 'Digital eye strain and lens-based prescribing: exploring the gap between evidence and clinical practice', Clinical and Experimental Optometry,

Journal articles | 2025

Trinh M; Cheung R; Nam J; Ng D; Nivison-Smith L; Ly A, 2025, 'High risk does not guarantee high accuracy—Evaluating the prognostic accuracy of OCT biomarkers for predicting late AMD', Ophthalmic and Physiological Optics, 45, pp. 1293 - 1301,

Journal articles | 2025

Trinh M; Duong A; Cheung R; Chen S; Ng D; Friedrich J; Hodge C; Nivison-Smith L; Ly A, 2025, 'Determinants of Intergrader Agreement for Key Retinal Photography and OCT Biomarkers in AMD', Translational Vision Science and Technology, 14,

Journal articles | 2025

Trinh M; Duong A; Cheung R; Chen S; Ng D; Friedrich J; Hodge C; Nivison-Smith L; Ly A, 2025, 'Proposal of a Simpler Eye-Level Risk Model Incorporating Reticular Pseudodrusen for the Clinical Prediction of Late Age-Related Macular Degeneration', Clinical and Experimental Ophthalmology, 53, pp. 936 - 945,

Journal articles | 2025

Trinh M; Tee YG; Nam J; Chen S; Schiller G; Friedrich J; Ng D; Ly A; Hodge C; Nivison-Smith L, 2025, 'Localising OCTA changes induced by the isometric hand-grip test to the superficial retina in neovascular age-related macular degeneration', Eye and Vision, 12,

Journal articles | 2025

Wang E; Doig GS; Ly A, 2025, 'An enhanced educational intervention for improving confidence in the eye health benefits of appropriate care for age-related macular degeneration: A randomized controlled trial', Health Education Research, 40,

Journal articles | 2024

Cheung R; Ly A, 2024, 'A survey of eyecare affordability among patients seen in collaborative care in Australia and factors contributing to cost barriers', Public Health Research and Practice, 34,

Journal articles | 2024

Ho S; Doig GS; Ly A, 2024, 'Diagnostic accuracy of community optometrists for age-related macular degeneration using colour fundus photographs: A pilot evaluation', Ophthalmic and Physiological Optics, 44, pp. 17 - 22,

Journal articles | 2024

Trinh M; Cheung R; Duong A; Nivison-Smith L; Ly A, 2024, 'OCT Prognostic Biomarkers for Progression to Late Age-related Macular Degeneration: A Systematic Review and Meta-analysis', Ophthalmology Retina, 8, pp. 553 - 565,

Journal articles | 2024

Trinh M; Kelly O; La M; Ly A, 2024, 'Linking physiology and demographics, non-ocular pathology and pharmaceutical drug use to standard OCT measures of the inner retina: The PPP project', Ophthalmic and Physiological Optics, 44, pp. 1128 - 1137,

Journal articles | 2023

Cheung R; Ho S; Ly A, 2023, 'Optometrists' attitudes toward using OCT angiography lag behind other retinal imaging types', Ophthalmic and Physiological Optics, 43, pp. 905 - 915,

Journal articles | 2023

Cheung R; Ly A; Wang H; Kalloniatis M; Nivison-Smith L, 2023, 'Evaluating the clinical relevance and reliability of outer retinal band length on optical coherence tomography in retinal disease: A cross-sectional study', BMJ Open, 13,

Journal articles | 2023

Ho S; Ly A; Ohno-Matsui K; Kalloniatis M; Doig GS, 2023, 'Diagnostic accuracy of OCTA and OCT for myopic choroidal neovascularisation: a systematic review and meta-analysis', Eye Basingstoke, 37, pp. 21 - 29,

Journal articles | 2023

Pan J; Ho S; Ly A; Kalloniatis M; Sowmya A, 2023, 'Drusen-aware model for age-related macular degeneration recognition', Ophthalmic and Physiological Optics, 43, pp. 668 - 679,

Journal articles | 2023

Wang E; Kalloniatis M; Ly A, 2023, 'Effective health communication for age-related macular degeneration: An exploratory qualitative study', Ophthalmic and Physiological Optics, 43, pp. 1278 - 1293,

Journal articles | 2022

Cheung R; Ly A; Katalinic P; Coroneo MT; Chang A; Kalloniatis M; Madigan MC; Nivison-Smith L; Chang A, 2022, 'Visualisation of peripheral retinal degenerations and anomalies with ocular imaging', Seminars in Ophthalmology, 37, pp. 554 - 582,

Journal articles | 2022

Ho S; Doig GS; Ly A, 2022, 'Attitudes of optometrists towards artificial intelligence for the diagnosis of retinal disease: A cross-sectional mail-out survey', Ophthalmic and Physiological Optics, 42, pp. 1170 - 1179,

Journal articles | 2022

Ho S; Kalloniatis M; Ly A, 2022, 'Clinical decision support in primary care for better diagnosis and management of retinal disease', Clinical and Experimental Optometry, 105, pp. 562 - 572,

Journal articles | 2022

Kalloniatis M; Wang H; Katalinic P; Ly A; Apel W; Nivison-Smith L; Kalloniatis KF, 2022, 'Ocular ischaemia: signs, symptoms, and clinical considerations for primary eye care practitioners', Clinical and Experimental Optometry, 105, pp. 117 - 134,

Journal articles | 2022

Ly A; Zangerl B; Kalloniatis M, 2022, 'Introduction of structured record keeping in age-related macular degeneration: a before and after study', Clinical and Experimental Optometry, 105, pp. 754 - 760,

Journal articles | 2022

Nam J; Ly A; Kalloniatis M; Nivison-Smith L, 2022, 'Multispectral pattern recognition measures change in drusen area in age-related macular degeneration with high congruency to expert graders', Scientific Reports, 12, pp. 7442,

Journal articles | 2022

Wang E; Kalloniatis M; Ly A, 2022, 'Assessment of patient education materials for age-related macular degeneration', Ophthalmic and Physiological Optics, 42, pp. 839 - 848,

Journal articles | 2021

Khou V; Ly A; Moore L; Markoulli M; Kalloniatis M; Yapp M; Hennessy M; Zangerl B, 2021, 'Review of referrals reveal the impact of referral content on the triage and management of ophthalmology wait lists', BMJ Open, 11, pp. e047246,

Journal articles | 2021

Tong J; Huang J; Khou V; Martin J; Kalloniatis M; Ly A, 2021, 'Topical Review: Assessment of Binocular Sensory Processes in Low Vision', Optometry and Vision Science, 98, pp. 310 - 325,

Journal articles | 2020

Hart KM; Abbott C; Ly A; Kalff S; Lek JJ; Milston R; Page G; Robertson B; Ayton L, 2020, 'Optometry Australia's chairside reference for the diagnosis and management of age-related macular degeneration', Clinical and Experimental Optometry, 103, pp. 254 - 264,

Journal articles | 2020

Huang J; Yapp M; Hennessy MP; Ly A; Masselos K; Agar A; Kalloniatis M; Zangerl B, 2020, 'Impact of referral refinement on management of glaucoma suspects in Australia', Clinical and Experimental Optometry, 103, pp. 675 - 683,

Journal articles | 2020

Jagadeesh D; Philip K; Fedtke C; Jong M; Ly A; Sankaridurg P, 2020, 'Posterior segment conditions associated with myopia and high myopia', Clinical and Experimental Optometry, 103, pp. 756 - 765,

Journal articles | 2020

Long JC; Blakely B; Mahmoud Z; Ly A; Zangerl B; Kalloniatis M; Assaad N; Yapp M; Clay-Williams R; Braithwaite J, 2020, 'Evaluation of a hospital-based integrated model of eye care for diabetic retinopathy assessment: A multimethod study', BMJ Open, 10, pp. e034699,

Journal articles | 2020

Luu W; Kalloniatis M; Bartley E; Tu M; Dillon L; Zangerl B; Ly A, 2020, 'A holistic model of low vision care for improving vision-related quality of life', Clinical and Experimental Optometry, 103, pp. 733 - 741,

Journal articles | 2020

Ly A; Wong E; Huang J; Yapp M; Masselos K; Hennessy M; Kalloniatis M; Zangerl B; Wong E, 2020, 'Glaucoma community care: Does ongoing shared care work?', International Journal of Integrated Care, 20, pp. 1 - 11,

Journal articles | 2020

Wang H; Ly A; Yapp M; Assaad N; Kalloniatis M, 2020, 'Multimodal imaging characteristics of congenital grouped hyper- and hypo-pigmented fundus lesions', Clinical and Experimental Optometry, 103, pp. 641 - 647,

Journal articles | 2019

Ly A; Banh J; Luu P; Huang J; Yapp M; Zangerl B, 2019, 'Interocular asymmetry of the superonasal retinal nerve fibre layer thickness and blood vessel diameter in healthy subjects', Plos One, 14, pp. e0226728,

Journal articles | 2019

Ly A; Phu J; Katalinic P; Kalloniatis M, 2019, 'An evidence-based approach to the routine use of optical coherence tomography', Clinical and Experimental Optometry, 102, pp. 242 - 259,

Journal articles | 2019

Ly A, 2019, 'Atlas of Ocular Optical Coherence Tomography Fedra Hajizadeh (editor) Springer, 2018, 483 pages, RRP: $586.95', Clinical and Experimental Optometry, 102, pp. 345 - 346,

Journal articles | 2018

Chiang J; Yapp M; Ly A; Hennessy MP; Kalloniatis M; Zangerl B, 2018, 'Retinal Nerve Fiber Layer Protrusion Associated with Tilted Optic Discs', Optometry and Vision Science, 95, pp. 239 - 246,

Journal articles | 2018

Ly A; Nivison-Smith L; Assaad N; Kalloniatis M, 2018, 'Multispectral pattern recognition reveals a diversity of clinical signs in intermediate age-related macular degeneration', Investigative Ophthalmology and Visual Science, 59, pp. 1790 - 1799,

Journal articles | 2018

Ly A; Nivison-Smith L; Zangerl B; Assaad N; Kalloniatis M, 2018, 'Advanced imaging for the diagnosis of age-related macular degeneration: a case vignettes study', Clinical and Experimental Optometry, 101, pp. 243 - 254,

Journal articles | 2018

Ly A; Yapp M; Nivison-Smith L; Assaad N; Hennessy M; Kalloniatis M, 2018, 'Developing prognostic biomarkers in intermediate age-related macular degeneration: their clinical use in predicting progression', Clinical and Experimental Optometry, 101, pp. 172 - 181,

Journal articles | 2018

Nivison-Smith L; Milston R; Chiang J; Ly A; Assaad N; Kalloniatis M, 2018, 'Peripheral retinal findings in populations with macular disease are similar to healthy eyes', Ophthalmic and Physiological Optics, 38, pp. 584 - 595,

Journal articles | 2017

Ly A; Nivison-Smith L; Assaad N; Kalloniatis M, 2017, 'Fundus Autofluorescence in Age-related Macular Degeneration', Optometry and Vision Science, 94, pp. 246 - 259,

Journal articles | 2017

Ly A; Nivison-Smith L; Hennessy M; Kalloniatis M, 2017, 'The advantages of intermediate-tier, inter-optometric referral of low risk pigmented lesions', Ophthalmic and Physiological Optics, 37, pp. 661 - 668,

Journal articles | 2017

Ly A; Nivison-Smith L; Zangerl B; Assaad N; Kalloniatis M, 2017, 'Self-reported optometric practise patterns in age-related macular degeneration', Clinical and Experimental Optometry, 100, pp. 718 - 728,

Journal articles | 2016

Ly A; Nivison-Smith L; Assaad N; Kalloniatis M, 2016, 'Infrared reflectance imaging in age-related macular degeneration', Ophthalmic and Physiological Optics, 36, pp. 303 - 316,

Journal articles | 2016

Ly A; Nivison-Smith L; Hennessy MP; Kalloniatis M, 2016, 'Collaborative care of non-urgent macular disease: a study of inter-optometric referrals', Ophthalmic and Physiological Optics, 36, pp. 632 - 642,

Journal articles | 2015

Ly A; Nivison-Smith L; Hennessy M; Kalloniatis M, 2015, 'Pigmented lesions of the retinal pigment epithelium', Optometry and Vision Science, 92, pp. 844 - 857,
Conference Papers | 2026

Farooq U; Trinh M; Ly A; Ameer A; Razzak I; Singh S, 2026, 'Asthma Identification through Multimodal Data Fusion: Towards Reliable Clinical Decision Support', in Proceedings of SPIE the International Society for Optical Engineering,

Conference Papers | 2025

Farooq U; Trinh M; Ly A; Ameer A; Razzak I; Singh S, 2025, 'Seeing Beyond the Airways: Asthma Prediction via Cross-Attention on Dual Retinal Modalities', in International Conference Image and Vision Computing New Zealand,

Conference Papers | 2025

Keay L; Ly A; Ren K; Pesudovs K; Kumaran S, 2025, 'Compliance to evidence-based recommendations which reduce risk of progression and enhance management of Age-Related Macular Degeneration', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC

Conference Papers | 2025

Ly A; Herse S; Lim C; Williams M-A; Stapleton F, 2025, 'Barriers to implementing artificial intelligence for age-related macular degeneration diagnostics', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY

Conference Papers | 2025

Nam J; Ly A; Herse S; Lim C; Williams M-A; Stapleton F, 2025, 'Stakeholder Perspectives of Implementation Barriers to Artificial Intelligence for Digital Diagnosis in Eye Care', US, presented at The Association for Research in Vision and Ophthalmology-, US, 03 May 2025

Preprints | 2025

Nam J; Ly A; Herse S; Lim C; Williams M-A; Stapleton F, 2025, Stakeholder Perspectives of Implementation Barriers of Artificial Intelligence in Eye Care: A qualitative framework-based study,

Conference Abstracts | 2025

Trinh M; Duong A; Cheung R; Chen S; Ng D; Friedrich J; Hodge C; Nivison-Smith L; Ly A, 2025, 'Proposal of a Simpler Risk Scoring Model Incorporating RPD for the Clinical Prediction of Late AMD', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, UT, Salt Lake City, Vol. 66, presented at ARVO Annual Meeting, UT, Salt Lake City, 04 May 2025 - 08 May 2025

Conference Abstracts | 2024

Kumaran SE; Pesudovs K; Ly A; Keay L, 2024, 'Mental health in people with macular disease', in Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology, WA, Seattle, Vol. 65, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), WA, Seattle, 05 May 2024 - 09 May 2024,

Preprints | 2024

Tang F; Trinh M; Duong A; Ly A; Stapleton F; Chen Z; Ge Z; Razzak I, 2024, Discriminating retinal microvascular and neuronal differences related to migraines: Deep Learning based Crossectional Study,

Conference Abstracts | 2024

Trinh M; Cheung R; Nam J; Nivison-Smith L; Ly A, 2024, 'Improving prognostic discrimination of late AMD using four OCT biomarkers', in Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology, WA, Seattle, Vol. 65, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), WA, Seattle, 05 May 2024 - 09 May 2024,

Conference Abstracts | 2024

Trinh M; Tang F; Ly A; Duong A; Stapleton F; Ge Z; Razzak I, 2024, 'Sight for sore heads - using CNNs to diagnose migraines', in Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology, WA, Seattle, Vol. 65, presented at ARVO Imaging in the Eye Conference, WA, Seattle, 04 May 2024 - 04 May 2024,

Conference Papers | 2023

Cheung R; Ho S; Ly A, 2023, 'Optometrists' attitudes toward using optical coherence tomography angiography (OCTA) lag behind other retinal imaging types', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, LA, New Orleans, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), LA, New Orleans, 23 April 2023 - 27 April 2023

Conference Papers | 2019

Ly A; Nivison-Smith L; Kalloniatis M, 2019, 'Pattern recognition for the distinction of drusen from reticular pseudodrusen', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, CANADA, Vancouver, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), CANADA, Vancouver, 28 April 2019 - 02 May 2019

Conference Papers | 2018

Levenkova A; Sowmya A; Kalloniatis M; Ly A; Ho A, 2018, 'Lesion detection in ultra-wide field retinal images for diabetic retinopathy diagnosis', in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Houston, Texas, United States, presented at SPIE Medical Imaging 2018, Houston, Texas, United States, 10 February 2018 - 15 February 2018,

Conference Papers | 2018

Zangerl B; Ly A; Hennessy MP; Agar A; Masselos K; Dance S; Yapp M; Kalloniatis M, 2018, 'Automated analysis of optic nerve head changes in patients with glaucoma', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, HI, Honolulu, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), HI, Honolulu, 21 April 2018 - 03 May 2018,

Conference Papers | 2017

Levenkova A; Sowmya A; Kalloniatis M; Ly A; Ho A, 2017, 'Automatic detection of diabetic retinopathy features in ultra-wide field retinal images', in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, SPIE, Orlando, Florida, United States, presented at SPIE Medical Imaging, 2017, Orlando, Florida, United States, 13 February 2017 - 16 February 2017,

Conference Papers | 2017

Ly A; Nivison-Smith L; Yapp M; Kalloniatis M, 2017, 'Referral pathways for non-urgent macular disease', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, MD, Baltimore, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), MD, Baltimore, 07 May 2017 - 11 May 2017

Conference Abstracts | 2016

Ly A; Nivison-Smith L; Zangerl B; Kalloniatis M, 2016, 'Practice patterns in age-related macular degeneration (AMD)', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, WA, Seattle, Vol. 57, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), WA, Seattle, 01 May 2016 - 05 May 2016

2025 ��Research Infrastructure Scheme (RIS): From Imaging to Insight: Advancing Retinal Disease Detection with Hyperspectral Detection with Hyperspectral Technology at 91ɫ��Ƭ, $131,499
2025 Macular Degeneration Research Grant from the Estate of the late Peter Anthony John Vild: Chat me up: designing a clinician and patient-verified chatbot to support AMD education beyond the consulting room, $19,824
2023 Macular Degeneration Research Grant from the Estate of the late Peter Anthony John Vild: ‘I spy with your little eye’ – using gaze tracking to identify barriers to OCT interpretation in age-related macular degeneration, $19,999
2023 Future Vision Foundation: Predicting Future Vision of Patients with Age-related Macular Degeneration, $24,977
2023 91ɫ��Ƭ Research Infrastructure Scheme (RIS): Spectralis Imaging Platform, $165,939
2021 Australian Human Rights Institute Small Grants Funding Scheme: Understanding health inequity and access to eye care in NSW/ACT, $2000
2020 Brolucizumab (RTH258) investigator-initiated research program, Novartis Pharmaceuticals: Attitudes and Barriers to Care in Age-related Macular Degeneration: The ABCs of AMD, $395,533

Optometry NSW/ACT International Women's Day Nominee, 2020
Australian government Research training program scholarship, 2017
Guide Dogs NSW/ACT Scholarship for postgraduate studies, 2014 - 2017
Australian government Postgraduate Award, 2014 - 2016

My research activities are focused on age-related macular degeneration and other posterior eye diseases in the areas of:

Imaging Science & Clinical Validity: Establishing what matters, how we measure it, and ensuring new imaging modalities are adopted effectively.
Frontline AI & Decision Support: Defining safe, effective roles for artificial intelligence and decision tools that people can trust and use.
Knowledge Translation, Health Communication & Equity: Turning evidence into action through multistakeholder co-design, communication, and systems design.

A listing of my previous publications can be found at:

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